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Part Descriptions

LP411023-7   HTR2A gene.c.614-2211T>C
The rs7997012 (c.614-2211T>C) variant is located in intron 2 of the HTR2A gene and codes for the 5-HT2A serotonin receptor. The variant has been identified as a marker of citalopram response. Patients with depression who are genotype AA are associated with increased likelihood of response when treated with citalopram as compared to genotype GG.[NCBI ClinVar ID: RCV000211197][OMIM: 182135#0003] Source: Regenstrief LOINC

LP40502-4   HTR2A gene
The HTR2A gene is located on chromosome 13 at position q14-q21 and encodes one of the receptors for serotonin, a neurotransmitter with many roles.[HGNC Gene ID:5293] Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] [NCBI Gene ID: 3356] Source: National Center for Biotechnology Information (NCBI) Gene, HTR2A gene

LOINC Names Get Info

Fully-Specified Name
HTR2A gene.c.614-2211T>C:Geno:Pt:Bld/Tiss:Nom:Molgen
Long Common Name
HTR2A gene c.614-2211T>C [Genotype] in Blood or Tissue by Molecular genetics method Nominal
Short Name
HTR2A c.614-2211T>C Geno Bld/T
Display Name
HTR2A gene c.614-2211T>C genotype Molgen (Bld/Tiss)
Consumer Name Alpha Get Info
HTR2A gene c.614-2211T>C genotype, Blood or tissue specimen

Part Model Get Info

  • Component
    HTR2A gene.c.614-2211T>C
    LP411023-7
    • Analyte
      HTR2A gene.c.614-2211T>C
      LP411023-7
      • Component Numerator
        HTR2A gene.c.614-2211T>C
        LP411023-7
        • Component Numerator Core
          HTR2A gene.c.614-2211T>C
          LP411023-7
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Geno
    LP345004-8
  • Time
    Pt
    LP6960-1
  • System
    Bld/Tiss
    LP7061-7
    • System Core
      Bld/Tiss
      LP7061-7
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Molgen
    LP6404-0

Example Answer List: LL3030-5

Source: Regenstrief LOINC
AnswerCodeScoreAnswer ID
T/T (wild type)LA21504-8
T/C (heterozygous)LA21505-5
C/C (homozygous)LA21506-3

Basic Attributes

Class
MOLPATH.PHARMG
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.68 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gen HTR2A c.614-2211T>C:Genotyp:Časový bod:Krev/tkáň:Nominální:Molekulární genetika
el-GRGreek (Greece)Γονίδιο HTR2A c.614-2211T>C:Geno:Pt:Αίμα/Ιστός:Nom:Μοριακή γενετική
Synonyms: C Geno MOLPATH MOLPATH.PHARMG Nom Pt Αίμα Αίμα/Ιστός Γονίδιο Γονίδιο HTR2A c.614-2211T>C Ιστός Μοριακή γενετική
es-ESSpanish (Spain)Gen HTR2A c.614-2211T> C:Genotipo:Punto temporal:Sangre o tejido:Nom:Genética molecular
es-MXSpanish (Mexico)Gen HTR2A c.614-2211T> C:Genotipo:Punto temporal:Sangre o tejido:Nominal:Genética molecular
fr-FRFrench (France)HTR2A gène mutation c.614-2211T>C:Génotype:Ponctuel:Sang/Tissu:Résultat nominal:Biologie moléculaire
it-ITItalian (Italy)HTR2A, gene.c.614-2211T>C:Geno:Pt:Sangue/Tess:Nom:Molgen
Synonyms: Farmacogenomica Gene HTR2A c.614-2211T>C Genetica molecolare Genotipo Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
pl-PLPolish (Poland)HTR2A gen.c.614-2211T>C:genotyp:punkt w czasie:krew lub tkanka:skala nominalna:genetyka molekularna
Synonyms: diagnostyka molekularna Gen HTR2A c.614-2211T>C wynik kategorialny
zh-CNChinese (China)HTR2A 基因.c.614-2211T>C:基因型:时间点:全血/组织:名义型:分子遗传学类实验室方法
Synonyms: 5-HT-2A 5-羟基色胺受体 2A 基因 5-羟色胺受体 2A 基因 5-羟色胺受体 2A 基因（5-hydroxytryptamine receptor 2A gene，5-HT-2A） C 型;丙;丙型 五羟色胺受体 2A 基因 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 血清素受体 2A 基因 血清素受体 2A 基因（serotonin receptor 2A gene） 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93190-7