Version 2.80

93353-1 CD64 Ag [Entitic number] on Neutrophil by Flow cytometry (FC)

Term Description

This term is intended to report the number of CD64 molecules per neutrophil.

Part Descriptions

LP268943-0   CD64
CD64, also known as Fc gamma receptor I, is a transmembrane glycoprotein that is part of the large immunoglobulin (Ig) superfamily. CD64 is encoded by 3 genes (FCγRI A-C), one for the transmembrane region and the other 2 for the Ig-like domains. CD64 is consitutively expressed on monocytes and macrophages (but inducible on neutrophils), and it has a pivotal role in antibody-dependent cytotoxicity and clearance of immune complexes. The presence of this molecule on neutrophils can aid in the diagnosis of infection and sepsis, and immuotherapeutic agents targeting CD64 have emerged as candidates for treatment of chronic inflammatory diseases such as atopic dermatitis, rheumatoid arthritis, and autoimmune disorders PMID: 28895912. Source: Regenstrief LOINC

LP411252-2   Neutrophil
Neutrophils are the most common form of white blood cells in healthy adults. Neutrophils are approximately 13 micrometers in diameter and have segmented nuclei with 3-5 lobes that are connected by thin strands of chromatin. (Practical Haematology; Barbara J. Bain, Imelda Bates, Mike A. Laffan,S. Mitchell Lewis; Eleventh edition; 2012) Neutrophils function to fight infection by both engulfing microorganisms and secreting lethal enzymes.
(https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0022058/) They are produced in the bone marrow and their primary function is to fight infection. Neutrophil numbers increase in the blood in response to acute bacterial infection, inflammation, necrosis or chronic myelogenous leukemia. Neutrophil levels are decreased in the following conditions: aplastic anemia, autoimmune disorder, cancer, chemotherapy, myelodysplastic syndrome and during a negative reaction to drugs. PMID: 24050624 [MedlinePlus Encyclopedia:19864] Source: Regenstrief LOINC

Fully-Specified Name

Component
CD64 Ag
Property
EntNum
Time
Pt
System
Neutrophil
Scale
Qn
Method
Flow cytometry

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67 (ADD)
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
93354-9 Neutrophil CD64 and Monocyte HLA DR panel - Blood by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) CD64 Αντιγόνο:EntNum:Pt:Ουδετερόφιλο:Qn:Κυτταρομετρία ροής
Synonyms: CD64 EntNum
es-ES Spanish (Spain) CD64 Antígeno:Número entítico:Punto temporal:Neutrófilo:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) CD64 Ag:Número entitic:Punto temporal:Neutrófilos:Cuantitativo:Citometría de flujo (FC)
fr-FR French (France) CD64 antigène:Nombre/entité:Ponctuel:Polynucléaires neutrophiles:Numérique:Cytométrie de flux
it-IT Italian (Italy) CD64, Ag:EntNum:Pt:Neutrofilo:Qn:Citometria a flusso
Synonyms: Citometria a flusso (FC) Modelli di superficie cellulare Numero entitico Punto nel tempo (episodio)
pl-PL Polish (Poland) CD64 Ag:liczba zawarta w:punkt w czasie:neutrofil:ilościowy:cytometria przepływowa (FC)
Synonyms: Antygen CD64 CD64
zh-CN Chinese (China) CD64 抗原:实体数量:时间点:嗜中性粒细胞:定量型:流式细胞测量术
Synonyms: Ag Fc gamma 受体 I FC gammaRI FC γ RI Fc γ受体 I Fc 受体 I FCR I 中性;中性粒;中性粒细胞;嗜中性 动态 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 实体计数 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 细胞标志物

Example Units

Unit Source
{#}/{cell} Example UCUM Units

93352-3 Neutrophils.CD64/Neutrophils in Blood by Flow cytometry (FC)

Part Descriptions

LP410916-3   Neutrophils.CD64
CD64, also known as Fc gamma receptor I, is a transmembrane glycoprotein that is part of the large immunoglobulin (Ig) superfamily. CD64 is encoded by 3 genes (FCγRI A-C), one for the transmembrane region and the other 2 for the Ig-like domains. CD64 is consitutively expressed on monocytes and macrophages (but inducible on neutrophils), and it has a pivotal role in antibody-dependent cytotoxicity and clearance of immune complexes. The presence of this molecule on neutrophils can aid in the diagnosis of infection and sepsis, and immuotherapeutic agents targeting CD64 have emerged as candidates for treatment of chronic inflammatory diseases such as atopic dermatitis, rheumatoid arthritis, and autoimmune disorders PMID: 28895912. Source: Regenstrief LOINC

Fully-Specified Name

Component
Neutrophils.CD64/Neutrophils
Property
NFr
Time
Pt
System
Bld
Scale
Qn
Method
Flow cytometry

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
93354-9 Neutrophil CD64 and Monocyte HLA DR panel - Blood by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Neutrófilos.CD64/100 neutrófilos:Fracción numérica:Punto temporal:Sangre:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Neutrófilos CD64 / 100 Neutrófilos:Fracción numérica:Punto temporal:Sangre:Cuantitativo:Citometría de flujo (FC)
fr-FR French (France) Polynucléaires neutrophiles CD64/100 polynucléaires neutrophiles:Fraction de nombres:Ponctuel:Sang:Numérique:Cytométrie de flux
it-IT Italian (Italy) Neutrofili.CD64/Neutrofili:NFr:Pt:Sangue:Qn:Citometria a flusso
Synonyms: Citometria a flusso (FC) Frazione numerica Modelli di superficie cellulare Neutrofili Neutrofili CD64 Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) neutrofielen.CD64/100 neutrofielen:getalsfractie:moment:bloed:kwantitatief:flowcytometrie
zh-CN Chinese (China) 嗜中性粒细胞.CD64/嗜中性粒细胞:计数型分数:时间点:全血:定量型:流式细胞测量术
Synonyms: Fc gamma 受体 I FC gammaRI FC γ RI Fc γ受体 I Fc 受体 I FCR I 中性;中性粒;中性粒细胞;嗜中性 动态 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 嗜中性粒细胞（中性、中性粒、中性粒细胞、嗜中性、Neu）.CD64 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 细胞标志物 血;血液

Example Units

Unit Source
% Example UCUM Units

93351-5 HLA-DR Ag [Entitic number] on Monocyte by Flow cytometry (FC)

Term Description

This term in intended to report the number of HLA-DR molecules per monocyte.

Part Descriptions

LP16794-7   HLA-DR
Found on B-cells, activated T-cells and Monocytes. Associated with B-cell leukemias/lymphomas, most AML (except M3), Reed-Sternberg cells and Peripheral T-cell lymphoma Source: Regenstrief Institute

Fully-Specified Name

Component
HLA-DR Ag
Property
EntNum
Time
Pt
System
Monocyte
Scale
Qn
Method
Flow cytometry

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67 (ADD)
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
93354-9 Neutrophil CD64 and Monocyte HLA DR panel - Blood by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Ανθρώπινα λευκοκυτταρικά αντιγόνα-DR Αντιγόνο:EntNum:Pt:Μονοκύτταρο:Qn:Κυτταρομετρία ροής
Synonyms: EntNum Ανθρώπινα λευκοκυτταρικά αντιγόνα Ανθρώπινα λευκοκυτταρικά αντιγόνα-DR
es-ES Spanish (Spain) HLA-DR+ Antígeno:Número entítico:Punto temporal:Monocito:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) HLA-DR Ag:Número entitic:Punto temporal:Monocitos:Cuantitativo:Citometría de flujo (FC)
fr-FR French (France) HLA-DR antigène:Nombre/entité:Ponctuel:Monocyte:Numérique:Cytométrie de flux
it-IT Italian (Italy) HLA-DR, Ag:EntNum:Pt:Monocita:Qn:Citometria a flusso
Synonyms: Citometria a flusso (FC) Modelli di superficie cellulare Numero entitico Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) HLA-DR Ag:aantal/eenheid:moment:monocyt:kwantitatief:flowcytometrie
Synonyms: antigeen
zh-CN Chinese (China) HLA-DR 抗原:实体数量:时间点:单核细胞:定量型:流式细胞测量术
Synonyms: Ag HLA 抗原;人类白细胞抗原;human leukocyte antigen HLA-DR Ag I3 人白细胞抗原 人类白细胞抗原 人类白细胞抗原（Human Leukocyte Antigen，HLA） 动态 单核;Mon 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 实体计数 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 白细胞抗原 细胞标志物

Example Units

Unit Source
{#}/{cell} Example UCUM Units

93350-7 Monocytes.HLA-DR/Monocytes in Blood by Flow cytometry (FC)

Part Descriptions

LP410918-9   Monocytes.HLA-DR
HLA-DR is a class II major histocompatibility complex (MHC) molecule that is required for antigen presentation by monocytes and other professional antigen presenting cells. A decrease in the expression of HLA-DR on the surface of monocytes is correlated with septic complications and found to have predictive value for fatal outcome PMID: 12802492 Source: Regenstrief LOINC

Fully-Specified Name

Component
Monocytes.HLA-DR/Monocytes
Property
NFr
Time
Pt
System
Bld
Scale
Qn
Method
Flow cytometry

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
93354-9 Neutrophil CD64 and Monocyte HLA DR panel - Blood by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Μονοκύτταρα.Ανθρώπινα λευκοκυτταρικά αντιγόνα-DR/Μονοκύτταρα:NFr:Pt:Αίμα:Qn:Κυτταρομετρία ροής
Synonyms: NFr Ανθρώπινα λευκοκυτταρικά αντιγόνα Ανθρώπινα λευκοκυτταρικά αντιγόνα-DR Μονοκύτταρα Μονοκύτταρα.Ανθρώπινα λευκοκυτταρικά αντιγόνα-DR
es-MX Spanish (Mexico) Monocitos HLA-DR / 100 Monocitos:Fracción numérica:Punto temporal:Sangre:Cuantitativo:Citometría de flujo (FC)
es-ES Spanish (Spain) Monocitos.HLA-DR/Monocitos:Fracción numérica:Punto temporal:Sangre:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
fr-FR French (France) Monocytes HLA-DR/100 monocytes:Fraction de nombres:Ponctuel:Sang:Numérique:Cytométrie de flux
it-IT Italian (Italy) Monociti.HLA-DR/Monociti:NFr:Pt:Sangue:Qn:Citometria a flusso
Synonyms: Citometria a flusso (FC) Frazione numerica Modelli di superficie cellulare Monociti HLA-DR Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) monocyten.HLA-DR/monocyten:getalsfractie:moment:bloed:kwantitatief:flowcytometrie
pl-PL Polish (Poland) Monocyty.HLA-DR/monocyty:frakcja liczbowa:punkt w czasie:krew:ilościowy:cytometria przepływowa (FC)
Synonyms: Monocyty Monocyty HLA-DR
zh-CN Chinese (China) 单核细胞.HLA-DR/单核细胞:计数型分数:时间点:全血:定量型:流式细胞测量术
Synonyms: HLA 抗原;人类白细胞抗原;human leukocyte antigen I3 人白细胞抗原 人类白细胞抗原 人类白细胞抗原（Human Leukocyte Antigen，HLA） 动态 单核;单 单核细胞（单核、Mon）.HLA-DR 单核细胞(复数) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 白细胞抗原 细胞标志物 血;血液

Example Units

Unit Source
% Example UCUM Units

69052-9 Flow cytometry specialist review of results

Fully-Specified Name

Component
Flow cytometry specialist review
Property
Imp
Time
Pt
System
XXX
Scale
Nar
Method

Basic Attributes

Class
MISC
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Observation
Common Test Rank Get Info
4439

Member of these Panels

LOINC Long Common Name
98239-7 CD154 expression and function panel - T cells by Flow cytometry (FC)
96415-5 DOCK8 expression panel - Blood by Flow cytometry (FC)
93354-9 Neutrophil CD64 and Monocyte HLA DR panel - Blood by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Befundint.Immunphän.
el-GR Greek (Greece) Ανασκόπηση ειδικού κυτταρομετρίας ροής:Imp:Pt:XXX:Nar:
Synonyms: Imp Ανασκόπηση ειδικού κυτταρομετρίας ροής Ροή
es-ES Spanish (Spain) Revisión del especilista en citometría de flujo:Impresión/interpretación del estudio:Punto temporal:XXX:Narrativo:
es-MX Spanish (Mexico) Revisión del especialista en citometría de flujo:Impresión / interpretación del estudio:Punto temporal:XXX:Narrativo:
fr-FR French (France) Validation cytométrie en flux:Interprétation:Ponctuel:Milieux divers:Résultat textuel:
it-IT Italian (Italy) Citometria a flusso, revisione specialista:Imp:Pt:XXX:Nar:
Synonyms: Impressione/interpretazione di studio Miscellanea Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) beoordeling door specialist in flowcytometrie:interpretatie:moment:XXX:tekstueel:
ru-RU Russian (Russian Federation) Проточная цитометрия специалист рецензия:Впчт:ТчкВрм:XXX:Опис:
Synonyms: Впечатление/интерпретация исследования Описательный Точка во времени;Момент
tr-TR Turkish (Turkey) Akış sitometri uzmanı değerlendirmesi:İzlnm:Zmlı:XXX:Öykü:
zh-CN Chinese (China) 流式细胞术专业人员审核:印象:时间点:XXX:叙述型:
Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 动态 印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型 时刻;随机;随意;瞬间 杂项;杂项类;杂项试验 流 流式细胞术专业人员回顾;流式细胞术专业人员审阅;流式细胞术专业人员审查;流式细胞术专业人员评审;流式细胞术专家审核;流式细胞仪专业人员审核 流量;流速;流体