93363-0
Plasma cell DNA content and proliferation panel - Bone marrow by Flow cytometry (FC)
Active
93362-2 Plasma cells monotypic population [Identifier] in Bone marrow by Flow cytometry (FC)
Part Descriptions
LP249103-5 Plasma cells.monotypic population
Plasma cells are fully differentiated B lymphocytes that produce and secrete a specific antibody.[https://www.cancer.gov/types/myeloma/patient/myeloma-treatment-pdq] Plasma cells typically produce a mixture of kappa and lambda light chains, but monotypic (or monoclonal) plasma cells produce either elevated kappa or lambda light chains.[http://hematologyoutlines.com/atlas_topics/76.html] Monotypic plasma cells are characteristic of disorders such as leukemia and multiple myeloma. The use of multi-parameter flow cytometry makes it possible to analyze large numbers of cells that distinguish intracellular antigens. Not only does such technology improve the diagnosis of monotypic populations, but it also is important for monitoring treatment and demonstrating smoldering disease. PMID: 21112041
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Plasma cells.monotypic population
- Property
- Prid
- Time
- Pt
- System
- Bone mar
- Scale
- Nom
- Method
- Flow cytometry
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL4476-9
Answer | Code | Score | Answer ID |
---|---|---|---|
No monotypic plasma cells | LA27565-3 | ||
Monotypic kappa plasma cells | LA27566-1 | ||
Monotypic lambda plasma cells | LA27567-9 | ||
Suspicious for kappa plasma cells | LA27568-7 | ||
Suspicious for lambda plasma cells | LA27569-5 | ||
Light-chain negative plasma cells | LA27570-3 |
Member of these Panels
LOINC | Long Common Name |
---|---|
93363-0 | Plasma cell DNA content and proliferation panel - Bone marrow by Flow cytometry (FC) |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Πλασματοκύτταρα.μονοτυπικός πληθυσμός: Synonyms: Prid Κύτταρα Πλάσμα Πλασματοκύτταρα Πλασματοκύτταρα.μονοτυπικός πληθυσμός |
es-MX | Spanish (Mexico) | Células plasmáticas población monotípica: |
es-ES | Spanish (Spain) | Células plasmáticas, población monoclonal: |
fr-FR | French (France) | Plasmocytes population monotypique: |
it-IT | Italian (Italy) | Plasmacellule.popolazione monotipica: Synonyms: Citometria a flusso (FC) Ematologia (coagulazione) conta differenziale Midollo osseo Popolazione monotipica plasmacellule Presenza o Identità Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | plasmacellen.monotypische populatie: |
pl-PL | Polish (Poland) | Plazmocyty, populacja monoklonalna: |
zh-CN | Chinese (China) | 浆细胞.单型群: Synonyms: 分类型应答; |
93021-4 Plasma cells with abnormal marker pattern/Cells counted in Bone marrow by Flow cytometry (FC)
Term Description
The percent of abnormal plasma cells (% minimal residual disease) detected by flow cytometry, calculated as number of abnormal plasma cells [LOINC: 93017-2] divided by the total number of cells counted [LOINC: 38257-2].
Part Descriptions
LP281527-4 Plasma cells.abnormal marker pattern
Plasma cells are fully differentiated B lymphocytes that produce and secrete a specific antibody.[https://www.cancer.gov/types/myeloma/patient/myeloma-treatment-pdq] Plasma cells typically produce a mixture of kappa and lambda light chains, but monotypic (or monoclonal) plasma cells produce either elevated kappa or lambda light chains.[http://hematologyoutlines.com/atlas_topics/76.html] Monotypic plasma cells are characteristic of disorders such as leukemia and multiple myeloma. The use of multi-parameter flow cytometry makes it possible to analyze large numbers of cells that distinguish intracellular antigens. Not only does such technology improve the diagnosis of monotypic populations, but it also is important for monitoring treatment and demonstrating smoldering disease. PMID: 21112041
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Plasma cells.abnormal marker pattern/Cells counted
- Property
- NFr
- Time
- Pt
- System
- Bone mar
- Scale
- Qn
- Method
- Flow cytometry
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.66
- Last Updated
- Version 2.66 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
93022-2 | Multiple myeloma minimal residual disease panel - Bone marrow by Flow cytometry (FC) |
93363-0 | Plasma cell DNA content and proliferation panel - Bone marrow by Flow cytometry (FC) |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Πλασματοκύτταρα.μη φυσιολογικό μοτίβο δείκτη/Μετρηθέντα κύτταρα: Synonyms: NFr Κύτταρα Μετρηθέντα κύτταρα Πλάσμα Πλασματοκύτταρα Πλασματοκύτταρα.μη φυσιολογικό μοτίβο δείκτη |
es-ES | Spanish (Spain) | Células plasmáticas con patrón de marcador anormal/Contaje celular: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Células plasmáticas patrón de marcador anormal / Células contadas: |
fr-FR | French (France) | Plasmocytes anormaux profil/cellules comptées: |
it-IT | Italian (Italy) | Plasmacellule, profilo marker anormale/Cellule contate: Synonyms: Citometria a flusso (FC) Ematologia (coagulazione) conta differenziale Frazione numerica Midollo osseo profilo marker anormale di plasmacellule Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | plasmacellen.afwijkend markerpatroon/getelde cellen: |
pl-PL | Polish (Poland) | Plazmocyty z nieprawidłową ekspresją markerów/zliczone komórki: |
zh-CN | Chinese (China) | 浆细胞.异常标志物模式/已计数的细胞: Synonyms: 不平常的 不正常的 动态 反常的 可用数量表示的; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
93361-4 Monotypic plasma cells in S phase/cells in Bone marrow by Flow cytometry (FC)
Term Description
In patients with newly diagnosed myeloma, a higher percentage of cells in S-phase may be associated with more aggressive disease.
Fully-Specified Name
- Component
- Plasma cells.monotypic.S phase/Cells
- Property
- NFr
- Time
- Pt
- System
- Bone mar
- Scale
- Qn
- Method
- Flow cytometry
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.79 (NAM)
- Change Reason
- Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
93363-0 | Plasma cell DNA content and proliferation panel - Bone marrow by Flow cytometry (FC) |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Πλασματοκύτταρα.μονοτυπική.φάση S/κύτταρα: Synonyms: NFr S Κύτταρα Πλάσμα Πλασματοκύτταρα Πλασματοκύτταρα.μονοτυπική.φάση S |
es-MX | Spanish (Mexico) | Células plasmáticas fase S monotípica / 100 células: |
es-ES | Spanish (Spain) | Células plasmáticas monotípicas en fase S/células: Synonyms: Cuantitativo |
fr-FR | French (France) | Plasmocytes population monotypique phase S/100 cellules: |
it-IT | Italian (Italy) | Plasmacellule.monotipiche.fase S/cellule: Synonyms: Citometria a flusso (FC) Frazione numerica Midollo osseo Patologia molecolare Plasmacellule monotipiche in fase S Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | plasmacellen.monotypische populatie.S-fase/cellen: |
pl-PL | Polish (Poland) | Plazmocyty, monoklonalne w fazie S/komórki: |
zh-CN | Chinese (China) | 浆细胞.单型.S 期/细胞: Synonyms: S 型 分子病理学; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
93360-6 Monotypic plasma cell DNA index in Bone marrow by Flow cytometry (FC)
Part Descriptions
LP410826-4 Monotypic plasma cell DNA index
DNA index (DI), which is associated with DNA ploidy, is a reflection of the average amount of DNA in the tumor cells. The DI can be measured by flow cytometry or image cytometry, both of which result in a DNA ploidy histogram, where the channel number on the x-axis represents fluorescent intensity or optical density for the two methods, respectively. All cells with the same quantity of DNA form one peak on the histogram, and with a population of normal cells, the largest peak represents diploid cells in G1 of the cell cycle, and a smaller peak represents cells in G2/M-phase. When there is a mixed population of normal and tumor cells, two or more G1 peaks will be seen, one for the normal cells and one or more for the tumor cells. The DI is calculated by dividing the channel number of the tumor cell G1 peak by the channel number of the normal (diploid control) G1 peak. If the tumor cells are diploid, the DI is 1, and if the cells are aneuploid, the DI is greater than or less than 1. For example, tetraploid cells have a DI of 2 because they have twice as much DNA content as normal diploid cells, and hypodiploid tumor cells have a DI of <1. PMID: 24532190
Source: Regenstrief LOINC
, PMID: 24532190
Fully-Specified Name
- Component
- Monotypic plasma cell DNA index
- Property
- Ratio
- Time
- Pt
- System
- Bone mar
- Scale
- Qn
- Method
- Flow cytometry
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
93363-0 | Plasma cell DNA content and proliferation panel - Bone marrow by Flow cytometry (FC) |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Μονοτυπικός δείκτης DNA πλασματοκυττάρων: Synonyms: DNA Ratio Δείκτης DNA Μονοτυπικός δείκτης DNA πλασματοκυττάρων Πλάσμα Πλασματοκύτταρο |
es-MX | Spanish (Mexico) | Índice de ADN de células plasmáticas monotípicas: |
es-ES | Spanish (Spain) | Índice de ADN de células plasmáticas monotípicas: Synonyms: Cuantitativo |
fr-FR | French (France) | Cellule plasmatique monotypique ADN index: |
it-IT | Italian (Italy) | Plasmacellule monotipiche, indice DNA: Synonyms: Citometria a flusso (FC) Indice di DNA Indice DNA delle plasmacellule monotipiche Midollo osseo Patologia molecolare Plasmocita Punto nel tempo (episodio) |
zh-CN | Chinese (China) | 单型浆细胞 DNA 指数: Synonyms: DI; |
Example Units
Unit | Source |
---|---|
{ratio} | Example UCUM Units |
93359-8 Monotypic plasma cell DNA ploidy [Type] in Bone marrow by Flow cytometry (FC)
Part Descriptions
LP410825-6 Monotypic plasma cell DNA ploidy
DNA index (DI), which is associated with DNA ploidy, is a reflection of the average amount of DNA in the tumor cells. The DI can be measured by flow cytometry or image cytometry, both of which result in a DNA ploidy histogram, where the channel number on the x-axis represents fluorescent intensity or optical density for the two methods, respectively. All cells with the same quantity of DNA form one peak on the histogram, and with a population of normal cells, the largest peak represents diploid cells in G1 of the cell cycle, and a smaller peak represents cells in G2/M-phase. When there is a mixed population of normal and tumor cells, two or more G1 peaks will be seen, one for the normal cells and one or more for the tumor cells. The DI is calculated by dividing the channel number of the tumor cell G1 peak by the channel number of the normal (diploid control) G1 peak. If the tumor cells are diploid, the DI is 1, and if the cells are aneuploid, the DI is greater than or less than 1. For example, tetraploid cells have a DI of 2 because they have twice as much DNA content as normal diploid cells, and hypodiploid tumor cells have a DI of <1. PMID: 24532190
Source: Regenstrief LOINC
, PMID: 24532190
Fully-Specified Name
- Component
- Monotypic plasma cell DNA ploidy
- Property
- Type
- Time
- Pt
- System
- Bone mar
- Scale
- Nom
- Method
- Flow cytometry
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67 (ADD)
- Order vs. Observation
- Observation
Example Answer List LL5361-2
Answer | Code | Score | Answer ID |
---|---|---|---|
Diploid | LA30218-4 | ||
Hypodiploid | LA30221-8 | ||
Hyperdiploid | LA30219-2 | ||
Tetraploid | LA30220-0 |
Member of these Panels
LOINC | Long Common Name |
---|---|
93363-0 | Plasma cell DNA content and proliferation panel - Bone marrow by Flow cytometry (FC) |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Μονοτυπική πλοειδία DNA πλασματοκυττάρων: Synonyms: DNA Type Μονοτυπική πλοειδία DNA πλασματοκυττάρων Πλάσμα Πλασματοκύτταρο Πλοειδία DNA |
es-MX | Spanish (Mexico) | Ploidía de ADN de células plasmáticas monotípicas: |
es-ES | Spanish (Spain) | Ploidía de ADN de células plasmáticas monotípicas: |
fr-FR | French (France) | Cellule plasmatique monotypique ADN ploïdie: |
it-IT | Italian (Italy) | Plasmacellule monotipiche, ploidia DNA: Synonyms: Citometria a flusso (FC) Midollo osseo Patologia molecolare Plasmocita Ploidia del DNA Ploidia DNA delle plasmacellule monotipiche Punto nel tempo (episodio) |
zh-CN | Chinese (China) | 单型浆细胞 DNA 倍性: Synonyms: DNA 倍数性; |
93358-0 Polyclonal plasma cells/Cells counted in Bone marrow by Flow cytometry (FC)
Fully-Specified Name
- Component
- Plasma cells.polyclonal/Cells counted
- Property
- NFr
- Time
- Pt
- System
- Bone mar
- Scale
- Qn
- Method
- Flow cytometry
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
93363-0 | Plasma cell DNA content and proliferation panel - Bone marrow by Flow cytometry (FC) |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Πλασματοκύτταρα.πολυκλωνικά/Μετρηθέντα κύτταρα: Synonyms: NFr Κύτταρα Μετρηθέντα κύτταρα Πλάσμα Πλασματοκύτταρα Πλασματοκύτταρα.πολυκλωνικά |
es-MX | Spanish (Mexico) | Células plasmáticas policlonales / Células contadas: |
es-ES | Spanish (Spain) | Células plamáticas policlonales/Contaje celular: Synonyms: Cuantitativo |
fr-FR | French (France) | Plasmocytes polyclonaux/cellules comptées: |
it-IT | Italian (Italy) | Plasmacellule.policlonali/Cellule contate: Synonyms: Citometria a flusso (FC) Ematologia (coagulazione) conta differenziale Frazione numerica Midollo osseo Plasmacellule policlonali Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | plasmacellen.polyklonaal/getelde cellen: |
pl-PL | Polish (Poland) | Plazmocyty, poliklonalne/zliczone komórki: |
zh-CN | Chinese (China) | 浆细胞.多克隆型/已计数的细胞: Synonyms: 动态 可用数量表示的; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
93020-6 Polyclonal plasma cells/Total plasma cells in Bone marrow by Flow cytometry (FC)
Term Description
The percent of normal (polyclonal) plasma cells in the patient's bone marrow, calculated as number of normal plasma cells [LOINC: 93018-0] divided by the total number of plasma cells [LOINC: 93019-8].
Fully-Specified Name
- Component
- Plasma cells.polyclonal/Plasma cells.total
- Property
- NFr
- Time
- Pt
- System
- Bone mar
- Scale
- Qn
- Method
- Flow cytometry
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.66
- Last Updated
- Version 2.66 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
93022-2 | Multiple myeloma minimal residual disease panel - Bone marrow by Flow cytometry (FC) |
93363-0 | Plasma cell DNA content and proliferation panel - Bone marrow by Flow cytometry (FC) |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Πλασματοκύτταρα.πολυκλωνικά/Πλασματοκύτταρα.συνολικά: Synonyms: NFr Κύτταρα Πλάσμα Πλασματοκύτταρα Πλασματοκύτταρα.πολυκλωνικά |
es-MX | Spanish (Mexico) | Células plasmáticas policlonales / células plasmáticas total: |
es-ES | Spanish (Spain) | Células plamáticas policlonales/Células totales del plasma: Synonyms: Cuantitativo |
fr-FR | French (France) | Plasmocytes polyclonaux/plasmocytes totaux: |
it-IT | Italian (Italy) | Plasmacellule.policlonali/Plasmacellule.totali: Synonyms: Citometria a flusso (FC) Ematologia (coagulazione) conta differenziale Frazione numerica Midollo osseo Plasmacellule policlonali Plasmacellule totali Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | plasmacellen.polyklonaal/plasmacellen.totaal: |
pl-PL | Polish (Poland) | Plazmocyty, poliklonalne/całkowita liczba plazmocytów: |
zh-CN | Chinese (China) | 浆细胞.多克隆型/浆细胞.总计: Synonyms: 全体数量 全部 共计 动态 可用数量表示的; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |