93785-4
Large B-cell lymphoma classification panel - Tissue
Active
93779-7 Large B-cell lymphoma and cell of origin [Type] in Tissue
Term Description
This term is intended to report the differentiation of primary mediastinal large B-cell lymphoma (PMBCL) from diffuse large B-cell lymphoma (DLBCL), and (if found to be DLBCL) to further subdivide DLBCL by cell of origin into the germinal center subtype or non-germinal center (activated B-cell) subtype.
Source: Regenstrief LOINC
Part Descriptions
LP411615-0 Large B-cell lymphoma and cell of origin
Distinguishing between large B-cell lymphomas is critical because the different forms often require distinct management. Diffuse large B-cell lymphoma (DLBCL) is the most common form, making up 30-40% of all non-Hodgkin's lymphomas. DLBCL is defined pathologically by large neoplastic cells with B-cell derivation and clinically by aggressive presentation, but differs from its former putative subtype, primary mediastinal large B-cell lymphoma (PMBCL), which is believed to arise from thymic medullary B cells. Since 2001, the WHO has recognized PMBCL as a distinct clinicopathologic disease from DLBCL, with likely distinct treatment options. PMBCL accounts for approximately 2% of patients with NHL, and tends to affect younger patients. PMID: 16720849. PMBCL is generally not further subclassified during a patient workup, whereas DLBCL can be further subdivided by cell of origin (COO) into germinal center type and non-germinal center (activated B-cell) type, the latter having significantly worse response to certain treatments PMID: 25135992.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Large B-cell lymphoma and cell of origin
- Property
- Type
- Time
- Pt
- System
- Tiss
- Scale
- Nom
- Method
Additional Names
- Short Name
- Lg B-cell lymph+COO Tiss
- Display Name
- Large B-cell lymphoma and cell of origin Nom (Tiss)
- Consumer Name Alpha Get Info
- Large b-cell lymphoma and cell of origin, Tissue
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67
- Order vs. Observation
- Observation
Preferred Answer List LL5436-2
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Primary mediastinal large B-cell lymphoma (PMBCL) | LA30366-1 | ||
| Germinal center B-cell type of diffuse large B-cell lymphoma | LA30367-9 | ||
| Activated B-cell type of diffuse large B-cell lymphoma | LA30368-7 | ||
| Unclear or unknown | LA10109-9 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93785-4 | Large B-cell lymphoma classification panel - Tissue |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Linfoma de células B grandes y células de origen: |
| es-MX | Spanish (Mexico) | Linfoma de células B grandes y células de origen: |
| it-IT | Italian (Italy) | Linfoma a grandi cellule B e cellula di origine: Synonyms: Patologia Punto nel tempo (episodio) Tessuto & |
| pl-PL | Polish (Poland) | Chłoniak z komórek B wg COO: Synonyms: Chłoniak z komórek B wg klasyfikacji Cell of Origin (COO) Pochodzenie |
| zh-CN | Chinese (China) | 大B细胞淋巴瘤和细胞起源: Synonyms: B 型 B 细胞 B-细胞 LBCL 分类型应答; |
93780-5 Primary mediastinal large B-cell lymphoma [Likelihood] in Tissue
Part Descriptions
LP411612-7 Primary mediastinal large B-cell lymphoma
Distinguishing between large B-cell lymphomas is critical because the different forms often require distinct management. Diffuse large B-cell lymphoma (DLBCL) is the most common form, making up 30-40% of all non-Hodgkin's lymphomas. DLBCL is defined pathologically by large neoplastic cells with B-cell derivation and clinically by aggressive presentation, but differs from its former putative subtype, primary mediastinal large B-cell lymphoma (PMBCL), which is believed to arise from thymic medullary B cells. Since 2001, the WHO has recognized PMBCL as a distinct clinicopathologic disease from DLBCL, with likely distinct treatment options. PMBCL accounts for approximately 2% of patients with NHL, and tends to affect younger patients. PMID: 16720849. PMBCL is generally not further subclassified during a patient workup, whereas DLBCL can be further subdivided by cell of origin (COO) into germinal center type and non-germinal center (activated B-cell) type, the latter having significantly worse response to certain treatments PMID: 25135992.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Primary mediastinal large B-cell lymphoma
- Property
- Likelihood
- Time
- Pt
- System
- Tiss
- Scale
- Qn
- Method
Additional Names
- Short Name
- Prim Med Lg B-cell lymph Tiss
- Display Name
- Primary mediastinal large B-cell lymphoma Qn (Tiss)
- Consumer Name Alpha Get Info
- Primary mediastinal large b-cell lymphoma, Tissue
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93785-4 | Large B-cell lymphoma classification panel - Tissue |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Linfoma de células B grandes mediastínico primario: |
| es-ES | Spanish (Spain) | Linfoma de células B grandes mediastínico primario: Synonyms: Cuantitativo |
| it-IT | Italian (Italy) | Linfoma primitivo del mediastino a grandi cellule B (PMBL): Synonyms: Patologia PMBL Punto nel tempo (episodio) Tessuto & |
| zh-CN | Chinese (China) | 原发性纵隔大B细胞淋巴瘤: Synonyms: B 型 B 细胞 B-细胞 LBCL 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| {risk} | Example UCUM Units |
93782-1 Large B-cell lymphoma [Type] in Tissue
Term Description
This term is intended to report the differentiation of primary mediastinal large B-cell lymphoma (PMBCL) from diffuse large B-cell lymphoma (DLBCL), but not report further subtyping of DLBCL.
Source: Regenstrief LOINC
Part Descriptions
LP411611-9 Large B-cell lymphoma
Distinguishing between large B-cell lymphomas is critical because the different forms often require distinct management. Diffuse large B-cell lymphoma (DLBCL) is the most common form, making up 30-40% of all non-Hodgkin's lymphomas. DLBCL is defined pathologically by large neoplastic cells with B-cell derivation and clinically by aggressive presentation, but differs from its former putative subtype, primary mediastinal large B-cell lymphoma (PMBCL), which is believed to arise from thymic medullary B cells. Since 2001, the WHO has recognized PMBCL as a distinct clinicopathologic disease from DLBCL, with likely distinct treatment options. PMBCL accounts for approximately 2% of patients with NHL, and tends to affect younger patients. PMID: 16720849. PMBCL is generally not further subclassified during a patient workup, whereas DLBCL can be further subdivided by cell of origin (COO) into germinal center type and non-germinal center (activated B-cell) type, the latter having significantly worse response to certain treatments PMID: 25135992.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Large B-cell lymphoma
- Property
- Type
- Time
- Pt
- System
- Tiss
- Scale
- Nom
- Method
Additional Names
- Short Name
- Lg B-cell lymph Tiss
- Display Name
- Large B-cell lymphoma Nom (Tiss)
- Consumer Name Alpha Get Info
- Large b-cell lymphoma, Tissue
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67
- Order vs. Observation
- Observation
Preferred Answer List LL5429-7
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Diffuse large B-cell lymphoma (DLBCL), NOS | LA26525-8 | ||
| Primary mediastinal large B-cell lymphoma (PMBCL) | LA30366-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93785-4 | Large B-cell lymphoma classification panel - Tissue |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Linfoma de células B grandes: |
| es-ES | Spanish (Spain) | Linfoma de células B grandes: |
| it-IT | Italian (Italy) | Linfoma a grandi cellule B: Synonyms: Patologia Punto nel tempo (episodio) Tessuto & |
| pl-PL | Polish (Poland) | Chłoniak z dużych komórek typu B: |
| zh-CN | Chinese (China) | 大B细胞淋巴瘤: Synonyms: B 型 B 细胞 B-细胞 LBCL 分类型应答; |
93784-7 Diffuse large B-Cell lymphoma cell of origin subclassification panel - Tissue
Term Description
This test is only indicated for patients with previously confirmed diagnosis of diffuse large B-cell lymphoma (DLBCL) for the purposes of cell-of-origin (COO) subclassification of the lymphoma to determine the cell of origin as either activated B-cell (likelihood of activated B-cell > 0.9) or germinal center B-cell (likelihood of activated B-cell < 0.1).
Source: Regenstrief LOINC
Part Descriptions
LP411617-6 Diffuse large B-Cell lymphoma cell of origin subclassification panel
Diffuse large B-cell lymphoma (DLBCL) represents approximately 30%-40% of all non-Hodgkin's lymphomas (NHLs), making it the most common lymphoid tumor. This group of diseases is defined pathologically by large neoplastic cells with B-cell derivation and clinically by aggressive presentation. Variants and subtypes have been recognized by World Health Organization (WHO) classifications based on unique morphologic and clinical presentations. DLBCL can be further subdivided by cell of origin (COO) into germinal center type and non-germinal center (activated B-cell) type, the latter having significantly worse response to certain treatments PMID: 25135992.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Diffuse large B-Cell lymphoma cell of origin subclassification panel
- Property
- -
- Time
- Pt
- System
- Tiss
- Scale
- -
- Method
Additional Names
- Short Name
- Diff lg B-cell Lymph COO Pnl Tiss
- Display Name
- Diffuse large B-Cell lymphoma cell of origin subclassification panel (Tiss)
- Consumer Name Alpha Get Info
- Diffuse large B-Cell lymphoma cell of origin subclassification panel, Tissue
Basic Attributes
- Class
- PANEL.PATH
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67
- Order vs. Observation
- Order
- Panel Type
- Panel
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93785-4 | Large B-cell lymphoma classification panel - Tissue |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Panel de subclasificación de linfoma difuso de células B grandes: |
| es-MX | Spanish (Mexico) | Panel de subclasificación de células de origen de linfoma difuso de células B grandes: |
| it-IT | Italian (Italy) | Linfoma diffuso a grandi cellule B, panel sottoclassificazione cellula di origine: Synonyms: Cellula di origine di linfoma diffuso a grandi cellule B Panel di sottoclassificazione cellula di origine di linfoma diffuso a grandi cellule B Patologia Punto nel tempo (episodio) Set di prescrizione per patologia Tessuto & |
| pl-PL | Polish (Poland) | Chłoniak rozlany pochodzący z dużych komórek B wg COO podgrupy: Synonyms: Chłoniak rozlany z dużych komórek B wg klasyfikacji Cell of Origin (COO) Chłoniaki rozlane z dużych komórek B Panel róznicujący rozlany chłoniak pochodzący z dużych komórek B na podtypy wg klasyfikacji Cell of Origin (COO) Pochodzenie |
| zh-CN | Chinese (China) | 弥漫性大B细胞淋巴瘤细胞起源亚分类组套: Synonyms: B 型 B 细胞 B-细胞 LBCL 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.病理学; |
93781-3 Diffuse large B-cell lymphoma.activated B-cell subtype [Likelihood] in Tissue
Term Description
This term reports the likelihood of the diffuse large B cell lymphoma (DLBCL) being of subtype activated B-cell versus germinal center B-cell/unclassifiable.
Source: Regenstrief LOINC
Part Descriptions
LP411618-4 Diffuse large B-cell lymphoma.activated B-cell subtype
Diffuse large B-cell lymphoma (DLBCL) represents approximately 30%-40% of all non-Hodgkin's lymphomas (NHLs), making it the most common lymphoid tumor. This group of diseases is defined pathologically by large neoplastic cells with B-cell derivation and clinically by aggressive presentation. Variants and subtypes have been recognized by World Health Organization (WHO) classifications based on unique morphologic and clinical presentations. DLBCL can be further subdivided by cell of origin (COO) into germinal center type and non-germinal center (activated B-cell) type, the latter having significantly worse response to certain treatments PMID: 25135992.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Diffuse large B-cell lymphoma.activated B-cell subtype
- Property
- Likelihood
- Time
- Pt
- System
- Tiss
- Scale
- Qn
- Method
Additional Names
- Short Name
- Diff Lg B-cell Lymph.ABC Tiss
- Display Name
- Diffuse large B-cell lymphoma.activated B-cell subtype Qn (Tiss)
- Consumer Name Alpha Get Info
- Diffuse large b-cell lymphoma.activated b-cell subtype, Tissue
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93784-7 | Diffuse large B-Cell lymphoma cell of origin subclassification panel - Tissue |
| 93785-4 | Large B-cell lymphoma classification panel - Tissue |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Linfoma difuso de células B grandes subtipo de células B activado: |
| es-ES | Spanish (Spain) | Linfoma difuso de células B grandes subtipo de células B activado: Synonyms: Cuantitativo |
| it-IT | Italian (Italy) | Linfoma diffuso a grandi cellule B.sottotipo di cellula B attivato: Synonyms: Patologia Punto nel tempo (episodio) Tessuto & |
| pl-PL | Polish (Poland) | Chłoniak rozlany z dużych komórek B.aktywowane komórki B podtyp: Synonyms: Chłoniak rozlany z dużych komórek B, podtyp z aktywowanych komórek B Chłoniaki rozlane z dużych komórek B |
| zh-CN | Chinese (China) | 弥漫性大B细胞淋巴瘤细胞.活化B细胞亚型: Synonyms: B 型 B 细胞 B-细胞 LBCL 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| {risk} | Example UCUM Units |
93783-9 Diffuse large B-cell lymphoma cell of origin [Type] in Tissue
Part Descriptions
LP411614-3 Diffuse large B-cell lymphoma cell of origin
Diffuse large B-cell lymphoma (DLBCL) represents approximately 30%-40% of all non-Hodgkin's lymphomas (NHLs), making it the most common lymphoid tumor. This group of diseases is defined pathologically by large neoplastic cells with B-cell derivation and clinically by aggressive presentation. Variants and subtypes have been recognized by World Health Organization (WHO) classifications based on unique morphologic and clinical presentations. DLBCL can be further subdivided by cell of origin (COO) into germinal center type and non-germinal center (activated B-cell) type, the latter having significantly worse response to certain treatments PMID: 25135992.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Diffuse large B-cell lymphoma cell of origin
- Property
- Type
- Time
- Pt
- System
- Tiss
- Scale
- Nom
- Method
Additional Names
- Short Name
- Diff Lg B-cell lymph COO Tiss
- Display Name
- Diffuse large B-cell lymphoma cell of origin Nom (Tiss)
- Consumer Name Alpha Get Info
- Diffuse large b-cell lymphoma cell of origin, Tissue
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67
- Order vs. Observation
- Observation
Preferred Answer List LL5430-5
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Activated B-cell type of diffuse large B-cell lymphoma | LA30368-7 | ||
| Germinal center B-cell type of diffuse large B-cell lymphoma | LA30367-9 | ||
| Unclassifiable B-cell | LA30369-5 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93784-7 | Diffuse large B-Cell lymphoma cell of origin subclassification panel - Tissue |
| 93785-4 | Large B-cell lymphoma classification panel - Tissue |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Célula difusa de linfoma de células B grandes de origen: |
| es-ES | Spanish (Spain) | Célula difusa de linfoma de células B grandes: |
| it-IT | Italian (Italy) | Linfoma diffuso a grandi cellule B, cellula di origine: Synonyms: Cellula di origine di linfoma diffuso a grandi cellule B Patologia Punto nel tempo (episodio) Tessuto & |
| pl-PL | Polish (Poland) | Chłoniak rozlany pochodzący z dużych komórek B wg COO: Synonyms: Chłoniak rozlany z dużych komórek B wg klasyfikacji Cell of Origin (COO) Chłoniaki rozlane z dużych komórek B Pochodzenie |
| zh-CN | Chinese (China) | 弥漫性大B细胞淋巴瘤细胞起源: Synonyms: B 型 B 细胞 B-细胞 LBCL 分类型应答; |