Version 2.78

Part Descriptions

LP411835-4   MYCN gene copy number
MYCN gene amplification studies evaluate the number of copies of the MYCN gene present in a single cell to aid in determining the prognosis of neurobastoma (NBL) patients. The MYCN gene encodes for a protein involved in the formation of tissues and organs during fetal development. It can also be an oncogene that regulates gene transcription. Amplification is determined based on the MYCN gene copy number and MYCN to centromere ratio (CEP2). An MYCN/CEP2 ratio of >= 2.0 is an indication of aggressive tumor progression of neuroblastoma. PMID: 9779703 Source: Regenstrief LOINC

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
MYCN gene copy number/Chromosome 2 copy number
Property
NRto
Time
Pt
System
Tiss
Scale
Qn
Method
FISH

Additional Names

Short Name
MYCN copy num/Chr 2 copy num Tiss FISH
Display Name
MYCN copy num/Chromosome 2 copy num FISH (Tiss) [# ratio]
Consumer Name Alpha Get Info
MYCN copy number/Chromosome 2 Copy Number, Tissue

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Número de copias del gen MYCN/Número de copias del cromosoma 2:Relación de número:Punto temporal:Tejido:Qn:Hibridación in situ fluoresente (FISH)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Número de copia del gen MYCN / número de copia del cromosoma 2:Proporción numérica:Punto temporal:Tejido y frotis:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR French (France) MYCN gène/chromosome 2 nombre de copie:Nombre/Nombre:Ponctuel:Tissu:Numérique:FISH
it-IT Italian (Italy) MYCN, numero copia gene/Cromosoma 2, numero copia:NRto:Pt:Tessuto:Qn:FISH
Synonyms: Ibridazione in situ fluorescente (FISH) Numero copia del cromosoma 2 Numero copia del gene MYCN Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Tessuto & Strisci
zh-CN Chinese (China) MYCN 基因拷贝数/染色体 2 拷贝数:计数型比率:时间点:组织与涂片:定量型:FISH
Synonyms: Ⅱ Fluorescent in situ hybridization;荧光原位杂交 II MYCN 基因拷贝（副本）数（数量、计数） 个数;数目 分子病理学;分子病理学试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染色体 2 拷贝（副本）数（数量、计数） 染色体二体型+染色体三体型 遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93797-9