Version 2.78

Term Description

Aneusomy (varying number) of chromosome 12 is evaluated by using a DNA probe that marks the centromeric region of chromosome 12. Such a probe is also called CEP12. The ratio of the number of signals of the MDM2 gene, also on chromosome 12, to the chromosome 12 signal [LOINC: 93809-2] can indicate whether or not there is amplification of the MDM2 gene.
Source: Regenstrief LOINC

Part Description

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
Chromosome 12 copy number/nucleus
Property
EntNum
Time
Pt
System
Tiss
Scale
Qn
Method
FISH

Additional Names

Short Name
Chr 12 copy num/nucleus EntNum Tiss FISH
Display Name
Chr 12 copy num/nucleus FISH (Tiss) [Entitic number]
Consumer Name Alpha Get Info
Chromosome 12 copy number/nucleus, Tissue

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Número de copias del cromosoma 12/núcleo:Número entítico:Punto temporal:Tejido:Qn:Hibridación in situ fluoresente (FISH)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Número de copias / núcleo del cromosoma 12:Número entitic:Punto temporal:Tejido y frotis:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR French (France) Chromosome 12 nombre de copie/noyaux:Nombre/entité:Ponctuel:Tissu:Numérique:FISH
it-IT Italian (Italy) Cromosoma 12, numero copia/nucleo:EntNum:Pt:Tessuto:Qn:FISH
Synonyms: Ibridazione in situ fluorescente (FISH) Numero copia del cromosoma 12 Numero entitico Patologia molecolare Punto nel tempo (episodio) Tessuto & Strisci
pl-PL Polish (Poland) Liczba kopii chromosomu 12/jądro:liczba zawarta w:punkt w czasie:tkanka i rozmazy:ilościowy:fluorescencyjna hybrydyzacja in situ (FISH)
zh-CN Chinese (China) 染色体 12 拷贝数/核:实体数量:时间点:组织与涂片:定量型:FISH
Synonyms: Fluorescent in situ hybridization;荧光原位杂交 个数;数目 分子病理学;分子病理学试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 实体计数 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染色体 12 拷贝（副本）数（数量、计数） 染色体二体型+染色体三体型 细胞核

Example Units

Unit Source
{#} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93804-3