93924-9
K Ag [Presence] on Red Blood Cells --post hematopoietic stem cell transplant
Active
Part Description
LP14926-7 K
Kell is highly polymorphic. It has two major codominant alleles, k and K, which result from a SNP (698C→T), and the corresponding k and K antigens differ by a single amino acid change (T193M). Mostly IgG antibodies, so IgM is uncommon. Anti-K does not bind complement. If hemolysis does occur, it is extravascular in nature. Anti-K can cause a severe hemolytic transfusion reaction and severe fetal anemia. In the RBC membrane, the Kell glycoprotein is covalently linked to the XK protein, a multipass membrane protein thought to have a role in transport. In the absence of XK, a condition called McLeod syndrome, Kell antigens are only weakly expressed and the RBCs are abnormal with spiky projections (acanthocytosis). Systemic findings include muscular dystrophy, cardiomyopathy, psychiatric disturbances, and neurological defects, such as loss of reflexes and movement disorders. The frequency of K antigens is 2% in Blacks, 9% in Caucasians, up to 25% in Arabs populations. Beck L, Blood groups and red cell antigens. NCBI Bookself [Internet Book], 2005.
Source: National Library of Medicine, K
Fully-Specified Name
- Component
- K Ag^post hematopoietic stem cell transplant
- Property
- PrThr
- Time
- Pt
- System
- RBC
- Scale
- Ord
- Method
Additional Names
- Short Name
- K Ag p HSCT RBC Ql
- Display Name
- K Ag post HSCT Ql (RBC)
- Consumer Name Alpha Get Info
- K antigen after stem cell transplant, Red blood cells
Example Answer List: LL5464-4
Source: Regenstrief LOINCAnswer | Code | Score | Answer ID |
---|---|---|---|
Double population Representing a mixed population of 2 types |
LA30465-1 | ||
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
93929-8 | Rh antigens and K Ag post hematopoietic stem cell transplant panel - Blood |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | K Antígeno^Postrasplante de células madre hematopoyéticas: |
es-MX | Spanish (Mexico) | K Ag ^ postrasplante de células madre hematopoyéticas: |
fr-FR | French (France) | KEL1 (K) antigène après allogreffe de cellules souches: |
it-IT | Italian (Italy) | K, Ag^post trapianto di cellule staminali emotopoietiche: Synonyms: Banca del sangue Globuli rossi Presenza o Soglia Punto nel tempo (episodio) |
zh-CN | Chinese (China) | K 抗原^在造血干细胞移植之后: Synonyms: Ag K 型 K 抗原 RBC; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=93924-9
Third Party Copyright
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