93949-6
ABO and Rh group panel - Cord blood
Active
34474-7 ABO and Rh group [Type] in Cord blood
Part Descriptions
LP36683-8 ABO & Rh group
In 1900, Landsteiner observed that the red cells of some individuals were agglutinated by the serum of others and his detailed report a year later heralded the discovery of the first human blood groups. His limited experiments on laboratory colleagues demonstrated three distinct groups; his pupils Von Decastello and Sturli discovered a fourth group in 1902. It was 25 years before these groups were shown to be inherited as Mendelian characters by means of three allelomorphic genes A, B and O and were, in fact, entities of one blood group system. For most of medicine this was considered a meaningless curiosity, but for those involved with the early development of transfusions it was quickly noted that transfusion of blood only of the same group could mean the difference between a successful outcome or a fatality. While various nomenclatures have been used to describe these factors, it was internationally decided in the mid-1940's that the characteristics would be individually identified as A, B, AB and O and the blood group system know as ABO. Since that time there have been billions of tests preformed and almost as many publications describing various aspects and associations of this blood group systems or its allelic products. The genes controlling the ABO system are located on the long arm of chromosome 9 and encode for either an a (1-3) N-acetylgalactosaminyltransferase (for A) or a (1,3) galactosyltransferase (for B). These transferases incorporate immunodominant sugars (GalNAc for A; Gal for B) on to one of four different types of oligosaccharide chains (type 2 is predominant on red cells, type 1 is found in secretions, plasma and some tissue) carried on glycosphingolipid or glycoprotein molecules. The placement of the A and B antigens is dependent upon the existence of a substrate produced by the Hh blood group system (ISBT # 018). Some individuals have weakened or variant expression of A and/or B which can be attributed to inheritance of variant forms of transferases. Those individuals that have neither transferases, inheritors of two amorph genes, are group O. To date, 14 A alleles, 14 B alleles and 8 O alleles have been identified at the molecular level and more remain to be found. The ABO antigens, as stated above are not restricted to the red blood cell membrane but can be found in saliva and all body fluids except spinal fluid if the individual has inherited a secretor gene. The antigens are also found on most epithelial and endothelial cells. It also appears on lymphocytes and platelets as it is adsorbed from the plasma. Alterations of ABH expression have been found in various forms of cancer. Furthermore, antigens of the ABO system may play a role in resistance to bacteria or viruses.
Source: Serum, Cells and Rare Fluid Exchange, ABO & Rh
Fully-Specified Name
- Component
- ABO & Rh group
- Property
- Type
- Time
- Pt
- System
- BldCo
- Scale
- Nom
- Method
Additional Names
- Short Name
- ABO + Rh BldCo
- Display Name
- ABO and Rh group (BldCo)
- Consumer Name Alpha Get Info
- ABO and Rh group, Cord blood
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 2.10
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 672
Preferred Answer List LL2972-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| O Pos Copyright http://snomed.info/sct ID:278147001 Blood group O Rh(D) positive (finding) | LA21321-7 | ||
| O Neg Copyright http://snomed.info/sct ID:278148006 Blood group O Rh(D) negative (finding) | LA21322-5 | ||
| B Pos Copyright http://snomed.info/sct ID:278150003 Blood group B Rh(D) positive (finding) | LA21327-4 | ||
| B Neg Copyright http://snomed.info/sct ID:278153001 Blood group B Rh(D) negative (finding) | LA21328-2 | ||
| AB Pos Copyright http://snomed.info/sct ID:278151004 Blood group AB Rh(D) positive (finding) | LA21323-3 | ||
| AB Neg Copyright http://snomed.info/sct ID:278154007 Blood group AB Rh(D) negative (finding) | LA21324-1 | ||
| A Pos Copyright http://snomed.info/sct ID:278149003 Blood group A Rh(D) positive (finding) | LA21325-8 | ||
| A Neg Copyright http://snomed.info/sct ID:278152006 Blood group A Rh(D) negative (finding) | LA21326-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93949-6 | ABO and Rh group panel - Cord blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Blutgr. AB0+Rh /BCO |
| es-ES | Spanish (Spain) | Grupo ABO y Rh: Synonyms: Grupos sanguíneos AB0 y Rh |
| es-AR | Spanish (Argentina) | grupo ABO + Rh: |
| es-MX | Spanish (Mexico) | ABO y grupo Rh: |
| et-EE | Estonian (Estonia) | ABO ja Rh: Synonyms: Juhuslik Nabaväädi veri |
| fr-FR | French (France) | ABO et RHD groupage: |
| fr-CA | French (Canada) | Groupe ABO & Rh: |
| it-IT | Italian (Italy) | ABO & Rh, gruppo: Synonyms: Banca del sangue Gruppo ABO & |
| ko-KR | Korean (Korea, Republic Of) | ABO+RH그룹: |
| nl-NL | Dutch (Netherlands) | AB0 & Rh-bloedgroep: |
| pt-BR | Portuguese (Brazil) | Grupo ABO+Rh: Synonyms: Rh typing; |
| ru-RU | Russian (Russian Federation) | ABO & Rh: Synonyms: Кровь пуповинная Номинальный; |
| tr-TR | Turkish (Turkey) | ABO ve Rh: Synonyms: Tür |
| zh-CN | Chinese (China) | ABO与Rh血型: Synonyms: ABO & |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
51892-8 ABO group [Type] in Cord blood
Part Descriptions
LP17806-8 ABO group
The ABO blood group antigens are encoded by one genetic locus, the ABO locus, which has three alternative forms: A, B, and O. A child receives one of these three forms from each parent, yielding six possible genotypes and four possible blood types (aka phenotypes: A, AB, B, O). ABO blood group antigens remain of prime importance in transfusion and transplantation medicine, and they are the most immunogenic of all the blood group antigens. ABO antibodies are of major clinical significance because they are naturally and universally occurring, and they are highly reactive. The distribution of the four phenotypes varies across the world - type O is the most common, followed by type A, then type B, and type AB is the least common. The ABO system is acknowledged in the pathogenesis of cardiovascular, infectious and neoplastic disorders, and pre-eclampsia. H antigen deficiency is known as the "Bombay phenotype" and is found in 1 in 10,000 people in India and 1 in 1 million people in Europe. [NCBI Books:NBK2267] PMID: 27177402[NCBI Books:NBK2264]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- ABO group
- Property
- Type
- Time
- Pt
- System
- BldCo
- Scale
- Nom
- Method
Additional Names
- Short Name
- ABO Group BldCo
- Display Name
- ABO group (BldCo)
- Consumer Name Alpha Get Info
- ABO group, Cord blood
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 2.24
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 1631
Preferred Answer List LL2419-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Group A Copyright http://snomed.info/sct ID:112144000 Blood group A (finding) | LA19710-5 | ||
| Group B Copyright http://snomed.info/sct ID:112149005 Blood group B (finding) | LA19709-7 | ||
| Group O Copyright http://snomed.info/sct ID:58460004 Blood group O (finding) | LA19708-9 | ||
| Group AB | LA28449-9 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93949-6 | ABO and Rh group panel - Cord blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Blutgruppe AB0 /BCO |
| es-MX | Spanish (Mexico) | Grupo ABO: |
| es-ES | Spanish (Spain) | Grupos sanguíneos AB0: |
| et-EE | Estonian (Estonia) | ABO-veregrupp: Synonyms: Juhuslik Nabaväädi veri |
| fr-FR | French (France) | ABO groupage: |
| fr-BE | French (Belgium) | Groupe ABO: |
| fr-CA | French (Canada) | Groupe ABO: |
| it-IT | Italian (Italy) | ABO, gruppo: Synonyms: Banca del sangue Gruppo ABO Punto nel tempo (episodio) Sangue di cordone ombelicale |
| nl-NL | Dutch (Netherlands) | AB0-bloedgroep: |
| pt-BR | Portuguese (Brazil) | Grupo ABO: Synonyms: Typ; |
| ru-RU | Russian (Russian Federation) | ABO группа: Synonyms: Кровь пуповинная Номинальный; |
| tr-TR | Turkish (Turkey) | ABO grubu: Synonyms: Tür |
| zh-CN | Chinese (China) | ABO 血型: Synonyms: 全血 - 脐带; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
14906-2 Rh [Type] in Cord blood
Part Descriptions
LP14541-4 Rh
Rh is the most complex of the blood groups systems, encompassing over 45 distinct antigens. The most clinical important antigen, D or Rho, was first described in 1940 and is present in over 85% of the population. Those individuals who lack the D antigen are considered to be Rh negative.
The Rh antigens are encoded by two highly homologous and closely linked genes on the short arm of chromosome 1. The RHD gene codes for the D antigen, or most of its components; RhCE gene codes the Cc and Ee antigens or their variants. The majority of the antigens within this system represent products of gene cross-over, point mutations or deletions within one or both genes.
The Rh antigens appear to be expressed only on red blood cell and they appear early during red cell development. Antibodies against the Rh antigens have caused severe and fatal transfusion reactions and hemolytic disease of the newborn. Rh antigens have been implicated in many diseases such as auto-immune hemolytic anemia, auto-Rh antibodies. Collect: One 4 mL green (sodium or lithium heparin) or serum separator tube. Also acceptable: lavender or pink (EDTA).
Source: Serum, Cells and Rare Fluid Exchange, Rh
Fully-Specified Name
- Component
- Rh
- Property
- Type
- Time
- Pt
- System
- BldCo
- Scale
- Nom
- Method
Additional Names
- Short Name
- Rh BldCo
- Display Name
- Rh Nom (BldCo)
- Consumer Name Alpha Get Info
- Rh, Cord blood
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 2643
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93949-6 | ABO and Rh group panel - Cord blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Rhesusfaktor /BCO |
| es-ES | Spanish (Spain) | Rh: |
| es-MX | Spanish (Mexico) | Rh: |
| es-AR | Spanish (Argentina) | Rh: |
| et-EE | Estonian (Estonia) | Rh: Synonyms: Juhuslik Nabaväädi veri |
| fr-FR | French (France) | RH1 (D): |
| fr-CA | French (Canada) | Rh: |
| fr-BE | French (Belgium) | Rh: |
| it-IT | Italian (Italy) | Rh: Synonyms: Banca del sangue Punto nel tempo (episodio) Sangue di cordone ombelicale |
| ko-KR | Korean (Korea, Republic Of) | RH: |
| nl-NL | Dutch (Netherlands) | Rh: |
| pl-PL | Polish (Poland) | Rh: |
| pt-BR | Portuguese (Brazil) | Fator Rh: Synonyms: Rh typing; |
| ru-RU | Russian (Russian Federation) | Rh: Synonyms: Кровь пуповинная Номинальный; |
| tr-TR | Turkish (Turkey) | Rh: Synonyms: Tür |
| zh-CN | Chinese (China) | Rh: Synonyms: D 分型; |
93948-8 D Ag [Presence] in Cord red blood cells
Fully-Specified Name
- Component
- D Ag
- Property
- PrThr
- Time
- Pt
- System
- RBCCo
- Scale
- Ord
- Method
Additional Names
- Short Name
- D Ag RBCCo Ql
- Display Name
- D Ag Ql (Cord RBC)
- Consumer Name Alpha Get Info
- D antigen, Cord Red Blood Cells
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67
- Order vs. Observation
- Both
Example Answer List LL5464-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Double population | LA30465-1 | ||
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93949-6 | ABO and Rh group panel - Cord blood |
| 93947-0 | Rh antigens and K Ag panel - Cord blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | D Antígeno: |
| es-MX | Spanish (Mexico) | D Ag: |
| et-EE | Estonian (Estonia) | D antigeen: Synonyms: Järgarvuline Juhuslik Nabaväädi erütrotsüüdid |
| fr-FR | French (France) | RH1 (D) antigène: |
| fr-CA | French (Canada) | D, Ag: |
| fr-BE | French (Belgium) | D Ag: Synonyms: Antigène |
| it-IT | Italian (Italy) | D, Ag: Synonyms: Banca del sangue Globuli rossi di cordone ombelicale Presenza o Soglia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | D Ag: Synonyms: antigeen rode bloedcellen uit navelstrengbloed |
| ru-RU | Russian (Russian Federation) | D Аг: Synonyms: Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | D Ag: Synonyms: Antijen Mevcut |
| zh-CN | Chinese (China) | D 抗原: Synonyms: Ag D 型抗原 Rh; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.