94428-0
HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC)
Active
94446-2 HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC)
Term Description
This panel was created for, but not restricted in use to, the Labscan single antigen bead multianalyte HLA antibody system detected with Luminex Labscan flow analyzer.
Source: Regenstrief LOINC
Part Descriptions
LP190780-9 HLA-A & B & C (class I) Ab.IgG panel
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-A & B & C (class I) Ab.IgG panel
- Property
- -
- Time
- Pt
- System
- Ser/Plas
- Scale
- -
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-A + B + C (class I) IgG Pnl SerPl FC
- Display Name
- HLA-A and B and C (class I) IgG panel FC
- Consumer Name Alpha Get Info
- HLA-A and B and C (class I) IgG Panel, Blood
Basic Attributes
- Class
- PANEL.HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Order
- Panel Type
- Panel
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Panel de anticuerpos IgG anti HLA-A, B y C (clase I): |
| es-MX | Spanish (Mexico) | Panel HLA-A & B & C (clase I) Ab.IgG: |
| fr-FR | French (France) | HLA-A et B et C (classe I) anticorps IgG panel: |
| it-IT | Italian (Italy) | HLA-A & B & C (classe I) Ab.IgG, panel: Synonyms: Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-A e B e C (classe I) Plasma Punto nel tempo (episodio) Set di prescrizione HLA Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-A & B & C (klasse I) As.IgG panel: |
| pl-PL | Polish (Poland) | HLA-A & B & C (klasa I) Ab.IgG panel: Synonyms: IgG Panel przeciwciał IgG do HLA-A i B i C (klasa I) Przeciwciała do antygenu I układu grupowego krwi Ii Przeciwciała IgG do HLA-A, B i C (klasa I) |
| zh-CN | Chinese (China) | HLA-A 与 B 与 C (I 类) 抗体.IgG 组套: Synonyms: A 型 A,B 型; |
48767-8 Annotation comment [Interpretation] Narrative
Term Description
This is an observation code indicating that a particular observation represents a free text annotation comment that can be appended to some other observation such as a lab result.
Source: Regenstrief LOINC
Observation Required in Panel
Optional
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Annotation comment
- Property
- Imp
- Time
- Pt
- System
- {system}
- Scale
- Nar
- Method
Additional Names
- Short Name
- Annotation comment Imp
Basic Attributes
- Class
- DOC.MISC
- Type
- Clinical
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 690
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 48769-4 | Continuity of Care panel |
| 55168-9 | Data Elements for Emergency Department Systems (DEEDS) Release 1.1 |
| 102116-1 | ESR1 gene mutation panel - Tissue by Molecular genetics method |
| 102117-9 | Gastrointestinal stromal tumor multigene mutation panel - Tissue by Molecular genetics method |
| 86535-2 | Healthcare associated infection report - recommended CDA R3 set |
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 101400-0 | Metanephrine, Normetanephrine, 3-Methoxytyramine panel - 24 hour Urine |
| 93321-8 | PT mixing study panel - Platelet poor plasma by Coagulation assay |
| 98412-0 | Retrograde ejaculation evaluation panel - Urine |
| 102118-7 | Rhabdomyolysis and Metabolic myopathy multigene panel - Blood or Tissue by Molecular genetics method |
| 102119-5 | Skeletal muscle channelopathy multigene panel - Blood or Tissue by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Comentario de anotación: |
| fr-FR | French (France) | Commentaire: |
| fr-CA | French (Canada) | Annotation commentaire: |
| fr-BE | French (Belgium) | Annotation commentaire: |
| it-IT | Italian (Italy) | Annotazioni e commenti: Synonyms: Documentazione miscellanea Impressione/interpretazione di studio Miscellanea Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | verklarend commentaar: |
| ru-RU | Russian (Russian Federation) | Аннотация комментарий: Synonyms: Впечатление/интерпретация исследования Описательный Поясняющий комментарий Точка во времени; |
| zh-CN | Chinese (China) | 注释: Synonyms: {体系} 印象是一种诊断陈述， |
94441-3 HLA-A and B and C (class I) IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Part Descriptions
LP190813-8 HLA-A & B & C (class I)
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-A & B & C (class I) Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-A+B+C (class I) IgG SerPl FC
- Display Name
- HLA-A and B and C (class I) IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-A and B and C (class I) IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5520-3
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-A1 | LA23858-6 | ||
| Anti-A2 | LA23859-4 | ||
| Anti-A3 | LA23860-2 | ||
| Anti-A9 | LA23861-0 | ||
| Anti-A11 | LA23863-6 | ||
| Anti-A28 | LA23864-4 | ||
| Anti-A29 | LA23865-1 | ||
| Anti-B7 | LA23870-1 | ||
| Anti-B12 | LA23872-7 | ||
| Anti-B13 | LA23873-5 | ||
| Anti-B22 | LA23876-8 | ||
| Anti-B27 | LA23877-6 | ||
| Anti-B35 | LA23878-4 | ||
| Anti-B41 | LA23880-0 | ||
| Anti-Cw1 | LA23886-7 | ||
| Anti-Cw4 | LA23888-3 | ||
| Anti-Cw5 | LA23889-1 | ||
| Anti-Cw3 | LA23890-9 | ||
| Anti-Cw7 | LA23892-5 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-A, B, C (clase I) IgG: |
| es-MX | Spanish (Mexico) | HLA-A y B y C (clase I) Ab.IgG: |
| fr-FR | French (France) | HLA-A et B et C (classe I) anticorps IgG: |
| it-IT | Italian (Italy) | HLA-A & B & C (classe I) Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-A e B e C (classe I) Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA A & B & C (klasse I) As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | HLA-A 与 B 与 C (I 类) 抗体.IgG: Synonyms: A 型 A,B 型; |
94442-1 HLA-A and B and C (class I) IgG with prozone effect [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Sometimes high titer antibody can be associated with low levels of detection (low mean fluorescence intensity, MFI, for the Luminex HLA bead assay), a phenomenon often referred to as the "prozone" effect. This term is intended to report those antibodies that were not detected with original sample, but became detectable after dilution or assay treatment. Some laboratories refer to these "prozone antigens observed", meaning those antigens for which the patient's antibody exhibited prozone effect.
Source: Regenstrief LOINC
Part Descriptions
LP417651-9 HLA-A & B & C (class I) Ab.IgG with prozone effect
HLA antibodies showing the prozone effect represent antibody specificities against HLA antigens that were not apparent in undiluted patient specimen, but became apparent after dilution. This so called prozone effect has been attributed to a number of putative mechanisms, including complement factor, antibody agglutination or competing IgM. Prozone effect can often be reversed with serum dilution or treatment with heat, EDTA, or DTT.
Source: Regenstrief LOINC
LP417651-9 HLA-A & B & C (class I) Ab.IgG with prozone effect
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-A & B & C (class I) Ab.IgG with prozone effect
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA class I Ab.IgG prozone SerPl FC
- Display Name
- HLA-A & B & C (class I) Ab.IgG with prozone effect FC Nom
- Consumer Name Alpha Get Info
- HLA-A & B & C (class I) Ab.IgG with prozone effect, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5520-3
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-A1 | LA23858-6 | ||
| Anti-A2 | LA23859-4 | ||
| Anti-A3 | LA23860-2 | ||
| Anti-A9 | LA23861-0 | ||
| Anti-A11 | LA23863-6 | ||
| Anti-A28 | LA23864-4 | ||
| Anti-A29 | LA23865-1 | ||
| Anti-B7 | LA23870-1 | ||
| Anti-B12 | LA23872-7 | ||
| Anti-B13 | LA23873-5 | ||
| Anti-B22 | LA23876-8 | ||
| Anti-B27 | LA23877-6 | ||
| Anti-B35 | LA23878-4 | ||
| Anti-B41 | LA23880-0 | ||
| Anti-Cw1 | LA23886-7 | ||
| Anti-Cw4 | LA23888-3 | ||
| Anti-Cw5 | LA23889-1 | ||
| Anti-Cw3 | LA23890-9 | ||
| Anti-Cw7 | LA23892-5 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-A, B, C (clase I) con efecto prozona por Ac IgG: |
| es-MX | Spanish (Mexico) | HLA-A & B & C (clase I) Ab.IgG con efecto prozona: |
| fr-FR | French (France) | HLA-A et B et C (classe I) anticorps IgG avec effet prozone: |
| it-IT | Italian (Italy) | HLA-A & B & C (classe I) Ab.IgG con effetto prozona: Synonyms: Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-A e B e C (classe I) HLA-Ae B e C (classe I) Ab.IgG con effetto prozona Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA A & B & C (klasse I) As.IgG met prozoneffect: |
| pl-PL | Polish (Poland) | HLA-A & B & C (klasa I) Ab.IgG z efektem prozony: Synonyms: IgG Przeciwciała do antygenu I układu grupowego krwi Ii Przeciwciała IgG do HLA-A, B i C (klasa I) Przeciwciała IgG do HLA-A, B i C (klasa I) ze efektem prozony |
| zh-CN | Chinese (China) | HLA-A 与 B 与 C (I 类) 抗体.IgG 伴前带效应: Synonyms: A 型 A,B 型; |
94430-6 HLA-A and B and C (class I) IgG low risk [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in the lower risk stratification of MFI values, but still detectable and possibly having a risk of rejection (For one lab this range was 500 < MFI < 1999).
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-A & B & C (class I) Ab.IgG low risk
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA class I Ab.IgG low risk SerPl FC
- Display Name
- HLA-A & B & C (class I) Ab.IgG low risk FC Nom
- Consumer Name Alpha Get Info
- HLA-A & B & C (class I) Ab.IgG low risk, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5520-3
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-A1 | LA23858-6 | ||
| Anti-A2 | LA23859-4 | ||
| Anti-A3 | LA23860-2 | ||
| Anti-A9 | LA23861-0 | ||
| Anti-A11 | LA23863-6 | ||
| Anti-A28 | LA23864-4 | ||
| Anti-A29 | LA23865-1 | ||
| Anti-B7 | LA23870-1 | ||
| Anti-B12 | LA23872-7 | ||
| Anti-B13 | LA23873-5 | ||
| Anti-B22 | LA23876-8 | ||
| Anti-B27 | LA23877-6 | ||
| Anti-B35 | LA23878-4 | ||
| Anti-B41 | LA23880-0 | ||
| Anti-Cw1 | LA23886-7 | ||
| Anti-Cw4 | LA23888-3 | ||
| Anti-Cw5 | LA23889-1 | ||
| Anti-Cw3 | LA23890-9 | ||
| Anti-Cw7 | LA23892-5 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-A, B, C (class I) bajo riesgo por Ac IgG: |
| es-MX | Spanish (Mexico) | HLA-A & B & C (clase I) Ab.IgG bajo riesgo: |
| fr-FR | French (France) | HLA-A et B et C (classe I) anticorps IgG MFI faible: |
| it-IT | Italian (Italy) | HLA-A & B & C (classe I) Ab.IgG, rischio basso: Synonyms: Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-A e B e C (classe I) Plasma Presenza o Identità Punto nel tempo (episodio) Rischio basso di HLA-A & |
| nl-NL | Dutch (Netherlands) | HLA A & B & C (klasse I) As.IgG laag risico: |
| pl-PL | Polish (Poland) | HLA-A & B & C (klasa I) Ab.IgG niskiego ryzyka: Synonyms: IgG Przeciwciała do antygenu I układu grupowego krwi Ii Przeciwciała IgG do HLA-A, B i C (klasa I) Przeciwciała IgG do HLA-A, B i C (klasa I) niskiego ryzyka |
| zh-CN | Chinese (China) | HLA-A 与 B 与 C (I 类) 抗体.IgG 低度风险: Synonyms: A 型 A,B 型; |
94450-4 HLA-A and B and C (class I) IgG intermediate risk [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in an intermediate risk stratification of MFI values (For one lab this was 4999 > MFI > 2000, but some laboratories use other values).
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-A & B & C (class I) Ab.IgG intermediate risk
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA class I Ab.IgG med risk SerPl FC
- Display Name
- HLA-A & B & C (class I) Ab.IgG intermediate risk FC Nom
- Consumer Name Alpha Get Info
- HLA-A & B & C (class I) Ab.IgG intermediate risk, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5520-3
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-A1 | LA23858-6 | ||
| Anti-A2 | LA23859-4 | ||
| Anti-A3 | LA23860-2 | ||
| Anti-A9 | LA23861-0 | ||
| Anti-A11 | LA23863-6 | ||
| Anti-A28 | LA23864-4 | ||
| Anti-A29 | LA23865-1 | ||
| Anti-B7 | LA23870-1 | ||
| Anti-B12 | LA23872-7 | ||
| Anti-B13 | LA23873-5 | ||
| Anti-B22 | LA23876-8 | ||
| Anti-B27 | LA23877-6 | ||
| Anti-B35 | LA23878-4 | ||
| Anti-B41 | LA23880-0 | ||
| Anti-Cw1 | LA23886-7 | ||
| Anti-Cw4 | LA23888-3 | ||
| Anti-Cw5 | LA23889-1 | ||
| Anti-Cw3 | LA23890-9 | ||
| Anti-Cw7 | LA23892-5 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-A, B, C (class I) riesgo intermedio por Ac IgG: |
| es-MX | Spanish (Mexico) | HLA-A & B & C (clase I) Ab.IgG riesgo intermedio: |
| fr-FR | French (France) | HLA-A et B et C (classe I) anticorps IgG MFI moyenne: |
| it-IT | Italian (Italy) | HLA-A & B & C (classe I) Ab.IgG, rischio intermedio: Synonyms: Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-A e B e C (classe I) Plasma Presenza o Identità Punto nel tempo (episodio) Rischio intermedio di HLA-A & |
| nl-NL | Dutch (Netherlands) | HLA A & B & C (klasse I) As.IgG intermediair risico: |
| pl-PL | Polish (Poland) | HLA-A & B & C (klasa I) Ab.IgG średniego ryzyka: Synonyms: IgG Przeciwciała do antygenu I układu grupowego krwi Ii Przeciwciała IgG do HLA-A, B i C (klasa I) Przeciwciała IgG do HLA-A, B i C (klasa I) średniego ryzyka |
| zh-CN | Chinese (China) | HLA-A 与 B 与 C (I 类) 抗体.IgG 中度风险: Synonyms: A 型 A,B 型; |
94449-6 HLA-A and B and C (class I) IgG high risk [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in the higher risk stratification of MFI values (For one lab this was MFI > 5000, but some laboratories use 10,000 or another value).
Source: Regenstrief LOINC
Part Descriptions
LP417652-7 HLA-A & B & C (class I) Ab.IgG high risk
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-A & B & C (class I) Ab.IgG high risk
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA class I Ab.IgG high risk SerPl FC
- Display Name
- HLA-A & B & C (class I) Ab.IgG high risk FC Nom
- Consumer Name Alpha Get Info
- HLA-A & B & C (class I) Ab.IgG high risk, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5520-3
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-A1 | LA23858-6 | ||
| Anti-A2 | LA23859-4 | ||
| Anti-A3 | LA23860-2 | ||
| Anti-A9 | LA23861-0 | ||
| Anti-A11 | LA23863-6 | ||
| Anti-A28 | LA23864-4 | ||
| Anti-A29 | LA23865-1 | ||
| Anti-B7 | LA23870-1 | ||
| Anti-B12 | LA23872-7 | ||
| Anti-B13 | LA23873-5 | ||
| Anti-B22 | LA23876-8 | ||
| Anti-B27 | LA23877-6 | ||
| Anti-B35 | LA23878-4 | ||
| Anti-B41 | LA23880-0 | ||
| Anti-Cw1 | LA23886-7 | ||
| Anti-Cw4 | LA23888-3 | ||
| Anti-Cw5 | LA23889-1 | ||
| Anti-Cw3 | LA23890-9 | ||
| Anti-Cw7 | LA23892-5 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-A, B, C (clase I) alto riesgo por Ac IgG: |
| es-MX | Spanish (Mexico) | HLA-A & B & C (clase I) Ab.IgG alto riesgo: |
| fr-FR | French (France) | HLA-A et B et C (classe I) anticorps IgG MFI forte: |
| it-IT | Italian (Italy) | HLA-A & B & C (classe I) Ab.IgG, rischio elevato: Synonyms: Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-A e B e C (classe I) Plasma Presenza o Identità Punto nel tempo (episodio) Rischio elevato di HLA-A & |
| nl-NL | Dutch (Netherlands) | HLA A & B & C (klasse I) As.IgG hoog risico: |
| pl-PL | Polish (Poland) | HLA-A & B & C (klasa I) Ab.IgG wysokiego ryzyka: Synonyms: IgG Przeciwciała do antygenu I układu grupowego krwi Ii Przeciwciała IgG do HLA-A, B i C (klasa I) Przeciwciała IgG do HLA-A, B i C (klasa I) wysokiego ryzyka |
| zh-CN | Chinese (China) | HLA-A 与 B 与 C (I 类) 抗体.IgG 高度风险: Synonyms: A 型 A,B 型; |
94445-4 HLA-A IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
This term will report antibodies detected against specific HLA antigens at the serologic type level. However, some high specificity assays,such as the Luminex single bead system, can detect epitopes at a more detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serotype, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-A antibody specificity.
Source: Regenstrief LOINC
Part Descriptions
LP193956-2 HLA-A Ab.IgG
HLA-A, along with HLA-B and HLA-C, is a class I major histocompatibility complex (MHC) receptor, which are keys to antigen presentation in the immune system. It is coded by the HLA-A gene located at human chromosome 6p21.3. The class I molecules are heterodimers composed of one alpha subunit (the product of the class I gene) and a beta subunit, beta2 microglobulin. The high variability of this class of molecules is likely key to protecting the humans from pathogens, as it is more likely that a subset of the population will be highly immune to any given pathogen, and this diversity is reflected in the hundreds to thousands of possible alleles. However, the variability in HLA is also the reason for transplant rejection, and the detection of HLA antibodies in the transplant recipient has become a critical pre-transplant assessment. [https://www.genecards.org/cgi-bin/carddisp.pl?gene=HLA-A]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-A Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-A IgG SerPl FC
- Display Name
- HLA-A IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-A IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5522-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-A2 (A*02:01) | LA30696-1 | ||
| Anti-A2 (A*02:03) | LA30697-9 | ||
| Anti-A11 (A*11:01) | LA30698-7 | ||
| Anti-A25 (A*25:01) | LA30699-5 | ||
| Anti-A29 (A*29:02) | LA30700-1 | ||
| Anti-A36 (A*36:01) | LA30701-9 | ||
| Anti-A68 (A*68:02) | LA30702-7 | ||
| Anti-A74 (A*74:01) | LA30703-5 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-A IgG: |
| es-MX | Spanish (Mexico) | HLA-A Ab.IgG: |
| fr-FR | French (France) | HLA-A anticorps IgG: |
| fr-BE | French (Belgium) | HLA-A Anticorps. IgG: Synonyms: Anticorps |
| fr-CA | French (Canada) | HLA-A, IgG: |
| it-IT | Italian (Italy) | HLA-A Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-A As.IgG: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | HLA-A Ат.IgG: Synonyms: Антитело Номинальный; |
| tr-TR | Turkish (Turkey) | HLA-A Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi |
| zh-CN | Chinese (China) | HLA-A 抗体.IgG: Synonyms: A IgG A 型 A 型抗体 Ab.IgG; |
94444-7 HLA-B IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
This term will report antibodies detected against specific HLA antigens at the serologic type level. However, some high specificity assays,such as the Luminex single bead system, can detect epitopes at a more detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serotype, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-B antibody specificity.
Source: Regenstrief LOINC
Part Descriptions
LP18320-9 HLA-B
Human Leukocyte Antigen B*27 (subtypes B*2701-2724) is a class I surface antigen encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6. It presents microbial antigens to T-cells and is strongly associated with certain immunity diseases (SpA spondyloarthropathies). In the general population, about 8% Caucasian, 4% African, 2-9% Chinese, and 0.1-0.5% Japanese have the HLA-B27 antigen. In Northern Scandinavia (Lapland), 24% of people are HLA-B27 positive while 1.8% have ankylosing spondylitis (AS). Mystery:The relationship between HLA-B27 and many diseases has not yet been fully elucidated. Though it is associated with a wide range of pathology, it does not appear to be the sole mediator in development of disease. For example, while nearly all people with ankylosing spondylitis (AS) are HLA-B27 positive, only a fraction of people with HLA-B27 ever develop AS.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, HLA-B (Wikipedia)
Fully-Specified Name
- Component
- HLA-B Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-B IgG SerPl FC
- Display Name
- HLA-B IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-B IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5526-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-B7 (B*07:02) | LA30704-3 | ||
| Anti-B75 (B*15:02) | LA30705-0 | ||
| Anti-B18 (B*18:01) | LA30706-8 | ||
| Anti-B27 (B*27:08) | LA30707-6 | ||
| Anti-B37 (B*37:01) | LA30708-4 | ||
| Anti-B57 (B*57:01) | LA30709-2 | ||
| Anti-B57 (B*57:03) | LA30710-0 | ||
| Anti-B82 (B*82:01) | LA30711-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-B IgG: |
| es-MX | Spanish (Mexico) | HLA-B Ab.IgG: |
| fr-FR | French (France) | HLA-B anticorps IgG: |
| fr-BE | French (Belgium) | HLA-B Anticorps. IgG: Synonyms: Anticorps |
| fr-CA | French (Canada) | HLA-B, IgG: |
| it-IT | Italian (Italy) | HLA-B Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-B As.IgG: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | HLA-B Ат.IgG: Synonyms: Антитело Номинальный; |
| tr-TR | Turkish (Turkey) | HLA-B Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi |
| zh-CN | Chinese (China) | HLA-B 抗体.IgG: Synonyms: Ab.IgG; |
94443-9 HLA-C IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
This term will report antibodies detected against specific HLA antigens at the serologic type level. However, some high specificity assays,such as the Luminex single bead system, can detect epitopes at a more detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serotype, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-C antibody specificity.
Source: Regenstrief LOINC
Part Descriptions
LP193954-7 HLA-C Ab.IgG
HLA-C, along with HLA-B and HLA-A, is a class I major histocompatibility complex (MHC) receptor, which are keys to antigen presentation in the immune system. It is coded by the HLA-C gene located on human chromosome 6. The class I molecules are heterodimers composed of one alpha subunit (the product of the class I gene) and a beta subunit, beta2 microglobulin. The high variability of this class of molecules is likely key to protecting the humans from pathogens, as it is more likely that a subset of the population will be highly immune to any given pathogen, and this diversity is reflected in the hundreds to thousands of possible alleles. However, the variability in HLA is also the reason for transplant rejection, and the detection of HLA antibodies in the transplant recipient has become a critical pre-transplant assessment. [https://www.genecards.org/cgi-bin/carddisp.pl?gene=HLA-C]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-C Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-C IgG SerPl FC
- Display Name
- HLA-C IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-C IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5527-8
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-Cw1 (C*01:02) | LA30712-6 | ||
| Anti-Cw10 (C*03:02) | LA30713-4 | ||
| Anti-Cw10 (C*03:04) | LA30714-2 | ||
| Anti-Cw4 (C*04:01) | LA30715-9 | ||
| Anti-Cw5 (C*05:01) | LA30716-7 | ||
| Anti-Cw12 (C*12:03) | LA30717-5 | ||
| Anti-Cw15 (C*15:02) | LA30718-3 | ||
| Anti-Cw16 (C*16:01) | LA30719-1 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-C IgG: |
| es-MX | Spanish (Mexico) | HLA-C Ab.IgG: |
| fr-FR | French (France) | HLA-C anticorps IgG: |
| fr-BE | French (Belgium) | HLA-C Anticorps. IgG: Synonyms: Anticorps |
| fr-CA | French (Canada) | HLA-C, IgG: |
| it-IT | Italian (Italy) | HLA-C Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-C As.IgG: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | HLA-C Ат.IgG: Synonyms: Антитело Номинальный; |
| tr-TR | Turkish (Turkey) | HLA-C Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi |
| zh-CN | Chinese (China) | HLA-C 抗体.IgG: Synonyms: Ab.IgG; |
72328-8 HLA-A+B+C (class I) IgG Ab [Presence] in Serum by Flow cytometry (FC)
Term Description
IgG antibodies to HLA class I antigens (A, B, and C) can be detected by flow cytometry in serum of pre and post-transplant organ recipients. A positive result is an indication of a sensitization to HLA antigens. This code is based on, but not exclusive to, the submitter's test kit, One Lambda's FlowPRA Screening Test, which uses beads coated with common and rare purified HLA Class I or II antigens.
Source: Regenstrief LOINC
Part Descriptions
LP156720-7 HLA-A+B+C Ab.IgG
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-A+B+C Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-A+B+C IgG Ser Ql FC
- Display Name
- HLA-A+B+C (class I) IgG FC Ql (S)
- Consumer Name Alpha Get Info
- HLA-A+B+C (class I) IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 72905-3 | Neutrophil Ab and HLA Ab screen panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-A+B+C IgG: |
| es-MX | Spanish (Mexico) | HLA-A + B + C Ab.IgG: |
| et-EE | Estonian (Estonia) | HLA-A+B+C antikehad.IgG: Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Seerum |
| fr-CA | French (Canada) | HLA-A+B+C, IgG: |
| fr-FR | French (France) | HLA-A+B+C anticorps IgG: |
| fr-BE | French (Belgium) | HLA-A+B+C Anticorps. IgG: Synonyms: Anticorps |
| it-IT | Italian (Italy) | HLA-A+B+C Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Presenza o Soglia Punto nel tempo (episodio) Siero |
| nl-NL | Dutch (Netherlands) | HLA-A+B+C As.IgG: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | HLA-A+B+C Ac.IgG: |
| ru-RU | Russian (Russian Federation) | HLA-A+B+C Ат.IgG: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | HLA-A+B+C Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi Mevcut |
| zh-CN | Chinese (China) | HLA-A+B+C 抗体.IgG: Synonyms: A 型 A,B 型; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
80737-0 Calculated panel reactive antibody - Serum
Term Description
A patient's "calculated panel reactive antibody" (cPRA) determines the likelihood that a transplant recipient and donor would be incompatible. The cPRA is calculated based on how many and which HLA antibodies the patient has compared to known information about the HLA antigen frequencies from ~1200 donors from 2003-2005. PMID: 19958328 The more antibodies the patient has and the more common the HLA antigens are in the donor pool, the higher the cPRA. Calculated cPRA is not the same as a patient's percent PRA, which is simply the percentage of a pool of donors (~100) to which a patient had reactive antibodies (see the HLA Ab panel [LOINC: 46993-2]). Note that "panel" is part of the antibody name and a single result is expected. This is not panel term.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Calculated panel reactive antibody
- Property
- RelRto
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
- Calculated
Additional Names
- Short Name
- cPRA Ser Calc
- Display Name
- Calculated panel reactive antibody Calc (S) [Relative ratio]
- Consumer Name Alpha Get Info
- Calculated panel reactive antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Formula (Readable)
cPRA calculator is available at https://optn.transplant.hrsa.gov/resources/allocation-calculators/cpra-calculator/
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Panel de anticuerpos reactivos calculados: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Anticuerpo reactivo de panel calculado: |
| fr-FR | French (France) | Anticorps réactifs panel calculé (cPRA): |
| it-IT | Italian (Italy) | Panel anticorpi reattivi calcolato: Synonyms: HLA tipizzazione tissutale antigeni-anticorpi Punto nel tempo (episodio) Rapporto Relativo Siero |
| nl-NL | Dutch (Netherlands) | berekend panel reactieve antistoffen: |
| zh-CN | Chinese (China) | 群体反应性抗体计算值: Synonyms: HLA 抗原; |
Example Units
| Unit | Source |
|---|---|
| {ratio} | Example UCUM Units |
8100-0 Specimen preparation [Type]
Fully-Specified Name
- Component
- Specimen preparation
- Property
- Type
- Time
- Pt
- System
- XXX
- Scale
- Nom
- Method
- *
Additional Names
- Short Name
- Specimen preparation
- Display Name
- Specimen preparation Nom (Specimen)
- Consumer Name Alpha Get Info
- Specimen preparation, Specimen
Basic Attributes
- Class
- SPEC
- Type
- Laboratory
- First Released
- Version 1.0h(2)
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 2431
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 96046-8 | B and T cell crossmatch panel - Patient serum and Donor blood by Flow cytometry (FC) |
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-AR | Spanish (Argentina) | preparación del espécimen: |
| es-ES | Spanish (Spain) | Preparación de la muestra: |
| es-MX | Spanish (Mexico) | Preparación de espécimen: |
| fr-CA | French (Canada) | Préparation de l'échantillon: |
| fr-FR | French (France) | Préparation du prélèvement: |
| fr-BE | French (Belgium) | Préparation de l'échantillon: |
| it-IT | Italian (Italy) | Campione, preparazione: Synonyms: Caratteristiche campione Preparazione del campione Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | monsterpreparatie: |
| pl-PL | Polish (Poland) | Przygotowanie próbki: |
| pt-BR | Portuguese (Brazil) | Preparação da amostra: Synonyms: Typ; |
| ru-RU | Russian (Russian Federation) | Образец подготовка: Synonyms: Номинальный; |
| zh-CN | Chinese (China) | 标本制备: Synonyms: 不明的; |
94431-4 Dilution factor [Titer] in Serum or Plasma
Fully-Specified Name
- Component
- Dilution factor
- Property
- Titr
- Time
- Pt
- System
- Ser/Plas
- Scale
- SemiQn
- Method
Additional Names
- Short Name
- Dilution factor Titr SerPl
- Display Name
- Dilution factor [Titer]
- Consumer Name Alpha Get Info
- Dilution factor, Blood
Basic Attributes
- Class
- MISC
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Factor de dilución: Synonyms: Semicuantitativo |
| es-MX | Spanish (Mexico) | Factor de dilución: |
| fr-FR | French (France) | Facteur de dilution: |
| it-IT | Italian (Italy) | Diluizione, fattore: Synonyms: Fattore di diluizione Miscellanea Plasma Punto nel tempo (episodio) Siero Siero o Plasma Titolo |
| nl-NL | Dutch (Netherlands) | verdunningsfactor: |
| zh-CN | Chinese (China) | 稀释倍数: Synonyms: 因素 效价; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |
94440-5 HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC)
Part Descriptions
LP190781-7 HLA-DP & DQ & DR (class II) Ab.IgG panel
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-DP & DQ & DR (class II) Ab.IgG panel
- Property
- -
- Time
- Pt
- System
- Ser/Plas
- Scale
- -
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA class II Ab.IgG Pnl SerPl FC
- Display Name
- HLA-DP and DQ and DR (class II) IgG panel FC
- Consumer Name Alpha Get Info
- HLA-DP and DQ and DR (class II) IgG Panel, Blood
Basic Attributes
- Class
- PANEL.HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Order
- Panel Type
- Panel
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Panel de anticuerpos IgG anti HLA-DP, DQ y DR (clase II): |
| es-MX | Spanish (Mexico) | Panel HLA-DP & DQ & DR (clase II) Ab.IgG: |
| fr-FR | French (France) | HLA-DP et DQ et DR (classe II) anticorps IgG panel: |
| it-IT | Italian (Italy) | HLA-DP & DQ & DR (classe II) Ab.IgG, panel: Synonyms: Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-DP e DQ e DR (classe II) Panel di HLA-DP e DQ e DR (classe II) IgG Plasma Pressione differenziale Punto nel tempo (episodio) Set di prescrizione HLA Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DP & DQ & DR (klasse II) As.IgG panel: |
| pl-PL | Polish (Poland) | HLA-DP & DQ & DR (klasa II) Ab.IgG panel: Synonyms: IgG Panel przeciwciał IgG do HLA-DP i DQ i DR (klasa II) Przeciwciała IgG do HLA-DP, DQ i DR (klasa II) |
| zh-CN | Chinese (China) | HLA-DP 与 DQ 与 DR (II 类) 抗体.IgG 组套: Synonyms: HLA II 类; |
48767-8 Annotation comment [Interpretation] Narrative
Term Description
This is an observation code indicating that a particular observation represents a free text annotation comment that can be appended to some other observation such as a lab result.
Source: Regenstrief LOINC
Observation Required in Panel
Optional
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Annotation comment
- Property
- Imp
- Time
- Pt
- System
- {system}
- Scale
- Nar
- Method
Additional Names
- Short Name
- Annotation comment Imp
Basic Attributes
- Class
- DOC.MISC
- Type
- Clinical
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 690
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 48769-4 | Continuity of Care panel |
| 55168-9 | Data Elements for Emergency Department Systems (DEEDS) Release 1.1 |
| 102116-1 | ESR1 gene mutation panel - Tissue by Molecular genetics method |
| 102117-9 | Gastrointestinal stromal tumor multigene mutation panel - Tissue by Molecular genetics method |
| 86535-2 | Healthcare associated infection report - recommended CDA R3 set |
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 101400-0 | Metanephrine, Normetanephrine, 3-Methoxytyramine panel - 24 hour Urine |
| 93321-8 | PT mixing study panel - Platelet poor plasma by Coagulation assay |
| 98412-0 | Retrograde ejaculation evaluation panel - Urine |
| 102118-7 | Rhabdomyolysis and Metabolic myopathy multigene panel - Blood or Tissue by Molecular genetics method |
| 102119-5 | Skeletal muscle channelopathy multigene panel - Blood or Tissue by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Comentario de anotación: |
| fr-FR | French (France) | Commentaire: |
| fr-CA | French (Canada) | Annotation commentaire: |
| fr-BE | French (Belgium) | Annotation commentaire: |
| it-IT | Italian (Italy) | Annotazioni e commenti: Synonyms: Documentazione miscellanea Impressione/interpretazione di studio Miscellanea Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | verklarend commentaar: |
| ru-RU | Russian (Russian Federation) | Аннотация комментарий: Synonyms: Впечатление/интерпретация исследования Описательный Поясняющий комментарий Точка во времени; |
| zh-CN | Chinese (China) | 注释: Synonyms: {体系} 印象是一种诊断陈述， |
80737-0 Calculated panel reactive antibody - Serum
Term Description
A patient's "calculated panel reactive antibody" (cPRA) determines the likelihood that a transplant recipient and donor would be incompatible. The cPRA is calculated based on how many and which HLA antibodies the patient has compared to known information about the HLA antigen frequencies from ~1200 donors from 2003-2005. PMID: 19958328 The more antibodies the patient has and the more common the HLA antigens are in the donor pool, the higher the cPRA. Calculated cPRA is not the same as a patient's percent PRA, which is simply the percentage of a pool of donors (~100) to which a patient had reactive antibodies (see the HLA Ab panel [LOINC: 46993-2]). Note that "panel" is part of the antibody name and a single result is expected. This is not panel term.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Calculated panel reactive antibody
- Property
- RelRto
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
- Calculated
Additional Names
- Short Name
- cPRA Ser Calc
- Display Name
- Calculated panel reactive antibody Calc (S) [Relative ratio]
- Consumer Name Alpha Get Info
- Calculated panel reactive antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Formula (Readable)
cPRA calculator is available at https://optn.transplant.hrsa.gov/resources/allocation-calculators/cpra-calculator/
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Panel de anticuerpos reactivos calculados: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Anticuerpo reactivo de panel calculado: |
| fr-FR | French (France) | Anticorps réactifs panel calculé (cPRA): |
| it-IT | Italian (Italy) | Panel anticorpi reattivi calcolato: Synonyms: HLA tipizzazione tissutale antigeni-anticorpi Punto nel tempo (episodio) Rapporto Relativo Siero |
| nl-NL | Dutch (Netherlands) | berekend panel reactieve antistoffen: |
| zh-CN | Chinese (China) | 群体反应性抗体计算值: Synonyms: HLA 抗原; |
Example Units
| Unit | Source |
|---|---|
| {ratio} | Example UCUM Units |
94432-2 HLA-DP and DQ and DR (class II) IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Part Descriptions
LP190815-3 HLA-DP & DQ & DR (class II)
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-DP & DQ & DR (class II) Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-DP+DQ+DR (class II) IgG SerPl FC
- Display Name
- HLA-DP and DQ and DR (class II) IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-DP and DQ and DR (class II) IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL3602-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DP1 | LA23895-8 | ||
| Anti-DP2 | LA23894-1 | ||
| Anti-DP3 | LA23897-4 | ||
| Anti-DP4 | LA23896-6 | ||
| Anti-DP5 | LA23898-2 | ||
| Anti-DP6 | LA23899-0 | ||
| Anti-DQ1 | LA23909-7 | ||
| Anti-DQ2 | LA23906-3 | ||
| Anti-DQ3 | LA23907-1 | ||
| Anti-DQ4 | LA23908-9 | ||
| Anti-DQ5(1) | LA23903-0 | ||
| Anti-DQ6(1) | LA23902-2 | ||
| Anti-DQ7(3) | LA23904-8 | ||
| Anti-DQ8(3) | LA23905-5 | ||
| Anti-DR1 | LA23910-5 | ||
| Anti-DR3 | LA23914-7 | ||
| Anti-DR4 | LA23915-4 | ||
| Anti-DR6 | LA23922-0 | ||
| Anti-DR7 | LA23916-2 | ||
| Anti-DR8 | LA23917-0 | ||
| Anti-DR10 | LA23918-8 | ||
| Anti-DR11(5) | LA23919-6 | ||
| Anti-DR12(5) | LA23920-4 | ||
| Anti-DR13(6) | LA23921-2 | ||
| Anti-DR14(6) | LA23923-8 | ||
| Anti-DR15(2) | LA23924-6 | ||
| Anti-DR16(2) | LA23925-3 | ||
| Anti-DR17(3) | LA23912-1 | ||
| Anti-DR18(3) | LA23913-9 | ||
| Anti-DR51 | LA23927-9 | ||
| Anti-DR52 | LA23926-1 | ||
| Anti-DR53 | LA23928-7 | ||
| Anti-DR103 | LA23911-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DP, DQ, DR (CLASE II) IgG: |
| es-MX | Spanish (Mexico) | HLA-DP y DQ y DR (clase II) Ab.IgG: |
| fr-FR | French (France) | HLA-DP et DQ et DR (classe II) anticorps IgG: |
| it-IT | Italian (Italy) | HLA-DP & DQ & DR (classe II) Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-DP e DQ e DR (classe II) Plasma Presenza o Identità Pressione differenziale Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DP & DQ & DR (klasse II) As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | HLA-DP 与 DQ 与 DR (II 类) 抗体.IgG: Synonyms: Ab.IgG; |
94429-8 HLA-DP and DQ and DR (class II) IgG low risk [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in the lower risk stratification of MFI values, but still detectable and possibly having a risk of rejection (For one lab this range was 500 < MFI < 1999).
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-DP & DQ & DR (class II) Ab.IgG low risk
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA class II Ab.IgG low risk SerPl FC
- Display Name
- HLA-DP & DQ & DR (class II) Ab.IgG low risk FC Nom
- Consumer Name Alpha Get Info
- HLA-DP & DQ & DR (class II) Ab.IgG low risk, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL3602-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DP1 | LA23895-8 | ||
| Anti-DP2 | LA23894-1 | ||
| Anti-DP3 | LA23897-4 | ||
| Anti-DP4 | LA23896-6 | ||
| Anti-DP5 | LA23898-2 | ||
| Anti-DP6 | LA23899-0 | ||
| Anti-DQ1 | LA23909-7 | ||
| Anti-DQ2 | LA23906-3 | ||
| Anti-DQ3 | LA23907-1 | ||
| Anti-DQ4 | LA23908-9 | ||
| Anti-DQ5(1) | LA23903-0 | ||
| Anti-DQ6(1) | LA23902-2 | ||
| Anti-DQ7(3) | LA23904-8 | ||
| Anti-DQ8(3) | LA23905-5 | ||
| Anti-DR1 | LA23910-5 | ||
| Anti-DR3 | LA23914-7 | ||
| Anti-DR4 | LA23915-4 | ||
| Anti-DR6 | LA23922-0 | ||
| Anti-DR7 | LA23916-2 | ||
| Anti-DR8 | LA23917-0 | ||
| Anti-DR10 | LA23918-8 | ||
| Anti-DR11(5) | LA23919-6 | ||
| Anti-DR12(5) | LA23920-4 | ||
| Anti-DR13(6) | LA23921-2 | ||
| Anti-DR14(6) | LA23923-8 | ||
| Anti-DR15(2) | LA23924-6 | ||
| Anti-DR16(2) | LA23925-3 | ||
| Anti-DR17(3) | LA23912-1 | ||
| Anti-DR18(3) | LA23913-9 | ||
| Anti-DR51 | LA23927-9 | ||
| Anti-DR52 | LA23926-1 | ||
| Anti-DR53 | LA23928-7 | ||
| Anti-DR103 | LA23911-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DP, DQ, DR (class II) bajo riesgo por Ac IgG: |
| es-MX | Spanish (Mexico) | HLA-DP & DQ & DR (clase II) Ab.IgG bajo riesgo: |
| fr-FR | French (France) | HLA-DP et DQ et DR (classe II) anticorps IgG MFI faible: |
| it-IT | Italian (Italy) | HLA-DP & DQ & DR (classe II) Ab.IgG, rischio basso: Synonyms: Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-DP e DQ e DR (classe II) Plasma Presenza o Identità Pressione differenziale Punto nel tempo (episodio) Rischio basso di HLA-DP e DQ eDR (classe II) Ab.IgG Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DP & DQ & DR (klasse II) As.IgG laag risico: |
| pl-PL | Polish (Poland) | HLA-DP & DQ & DR (klasa II) Ab.IgG niskiego ryzyka: Synonyms: IgG Przeciwciała IgG do HLA-DP, DQ i DR (klasa II) Przeciwciała IgG do HLA-DP, DQ i DR (klasa II) niskiego ryzyka |
| zh-CN | Chinese (China) | HLA-DP 与 DQ 与 DR (II 类) 抗体.IgG 低度风险: Synonyms: HLA II 类; |
94448-8 HLA-DP and DQ and DR (class II) IgG intermediate risk [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in an intermediate risk stratification of MFI values (For one lab this was 4999 > MFI > 2000, but some laboratories use other values).
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-DP & DQ & DR (class II) Ab.IgG intermediate risk
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA class II Ab.IgG med risk SerPl FC
- Display Name
- HLA-DP & DQ & DR (class II) Ab.IgG intermediate risk FC Nom
- Consumer Name Alpha Get Info
- HLA-DP & DQ & DR (class II) Ab.IgG intermediate risk, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL3602-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DP1 | LA23895-8 | ||
| Anti-DP2 | LA23894-1 | ||
| Anti-DP3 | LA23897-4 | ||
| Anti-DP4 | LA23896-6 | ||
| Anti-DP5 | LA23898-2 | ||
| Anti-DP6 | LA23899-0 | ||
| Anti-DQ1 | LA23909-7 | ||
| Anti-DQ2 | LA23906-3 | ||
| Anti-DQ3 | LA23907-1 | ||
| Anti-DQ4 | LA23908-9 | ||
| Anti-DQ5(1) | LA23903-0 | ||
| Anti-DQ6(1) | LA23902-2 | ||
| Anti-DQ7(3) | LA23904-8 | ||
| Anti-DQ8(3) | LA23905-5 | ||
| Anti-DR1 | LA23910-5 | ||
| Anti-DR3 | LA23914-7 | ||
| Anti-DR4 | LA23915-4 | ||
| Anti-DR6 | LA23922-0 | ||
| Anti-DR7 | LA23916-2 | ||
| Anti-DR8 | LA23917-0 | ||
| Anti-DR10 | LA23918-8 | ||
| Anti-DR11(5) | LA23919-6 | ||
| Anti-DR12(5) | LA23920-4 | ||
| Anti-DR13(6) | LA23921-2 | ||
| Anti-DR14(6) | LA23923-8 | ||
| Anti-DR15(2) | LA23924-6 | ||
| Anti-DR16(2) | LA23925-3 | ||
| Anti-DR17(3) | LA23912-1 | ||
| Anti-DR18(3) | LA23913-9 | ||
| Anti-DR51 | LA23927-9 | ||
| Anti-DR52 | LA23926-1 | ||
| Anti-DR53 | LA23928-7 | ||
| Anti-DR103 | LA23911-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DP, DQ, DR (class II) riesgo intermedio por Ac IgG: |
| es-MX | Spanish (Mexico) | HLA-DP & DQ & DR (clase II) Ab.IgG riesgo intermedio: |
| fr-FR | French (France) | HLA-DP et DQ et DR (classe II) anticorps IgG MFI moyenne: |
| it-IT | Italian (Italy) | HLA-DP & DQ & DR (classe II) Ab.IgG, rischio intermedio: Synonyms: Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-DP e DQ e DR (classe II) Plasma Presenza o Identità Pressione differenziale Punto nel tempo (episodio) Rischio intermedio di HLA-DP e DQ e DR (classe II) IgG Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DP & DQ & DR (klasse II) As.IgG intermediair risico: |
| pl-PL | Polish (Poland) | HLA-DP & DQ & DR (klasa II) Ab.IgG średniego ryzyka: Synonyms: IgG Przeciwciała IgG do HLA-DP, DQ i DR (klasa II) Przeciwciała IgG do HLA-DP, DQ i DR (klasa II) średniego ryzyka |
| zh-CN | Chinese (China) | HLA-DP 与 DQ 与 DR (II 类) 抗体.IgG 中度风险: Synonyms: HLA II 类; |
94447-0 HLA-DP and DQ and DR (class II) IgG high risk [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in the higher risk stratification of MFI values (For one lab this was MFI > 5000, but some laboratories use 10,000 or another value).
Source: Regenstrief LOINC
Part Descriptions
LP417656-8 HLA-DP & DQ & DR (class II) Ab.IgG high risk
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-DP & DQ & DR (class II) Ab.IgG high risk
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA class II Ab.IgG high risk SerPl FC
- Display Name
- HLA-DP & DQ & DR (class II) Ab.IgG high risk FC Nom
- Consumer Name Alpha Get Info
- HLA-DP & DQ & DR (class II) Ab.IgG high risk, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL3602-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DP1 | LA23895-8 | ||
| Anti-DP2 | LA23894-1 | ||
| Anti-DP3 | LA23897-4 | ||
| Anti-DP4 | LA23896-6 | ||
| Anti-DP5 | LA23898-2 | ||
| Anti-DP6 | LA23899-0 | ||
| Anti-DQ1 | LA23909-7 | ||
| Anti-DQ2 | LA23906-3 | ||
| Anti-DQ3 | LA23907-1 | ||
| Anti-DQ4 | LA23908-9 | ||
| Anti-DQ5(1) | LA23903-0 | ||
| Anti-DQ6(1) | LA23902-2 | ||
| Anti-DQ7(3) | LA23904-8 | ||
| Anti-DQ8(3) | LA23905-5 | ||
| Anti-DR1 | LA23910-5 | ||
| Anti-DR3 | LA23914-7 | ||
| Anti-DR4 | LA23915-4 | ||
| Anti-DR6 | LA23922-0 | ||
| Anti-DR7 | LA23916-2 | ||
| Anti-DR8 | LA23917-0 | ||
| Anti-DR10 | LA23918-8 | ||
| Anti-DR11(5) | LA23919-6 | ||
| Anti-DR12(5) | LA23920-4 | ||
| Anti-DR13(6) | LA23921-2 | ||
| Anti-DR14(6) | LA23923-8 | ||
| Anti-DR15(2) | LA23924-6 | ||
| Anti-DR16(2) | LA23925-3 | ||
| Anti-DR17(3) | LA23912-1 | ||
| Anti-DR18(3) | LA23913-9 | ||
| Anti-DR51 | LA23927-9 | ||
| Anti-DR52 | LA23926-1 | ||
| Anti-DR53 | LA23928-7 | ||
| Anti-DR103 | LA23911-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DP, DQ, DR (CLASE II) alto riesgo por Ac IgG: |
| es-MX | Spanish (Mexico) | HLA-DP & DQ & DR (clase II) Ab.IgG alto riesgo: |
| fr-FR | French (France) | HLA-DP et DQ et DR (classe II) anticorps IgG MFI forte: |
| it-IT | Italian (Italy) | HLA-DP & DQ & DR (classe II) Ab.IgG, rischio elevato: Synonyms: Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-DP e DQ e DR (classe II) Plasma Presenza o Identità Pressione differenziale Punto nel tempo (episodio) Rischio elevato di HLA-DP & |
| nl-NL | Dutch (Netherlands) | HLA-DP & DQ & DR (klasse II) As.IgG hoog risico: |
| pl-PL | Polish (Poland) | HLA-DP & DQ & DR (klasa II) Ab.IgG wysokiego ryzyka: Synonyms: IgG Przeciwciała IgG do HLA-DP, DQ i DR (klasa II) Przeciwciała IgG do HLA-DP, DQ i DR (klasa II) wysokiego ryzyka |
| zh-CN | Chinese (China) | HLA-DP 与 DQ 与 DR (II 类) 抗体.IgG 高度风险: Synonyms: HLA II 类; |
94433-0 HLA-DP and DQ and DR (class II) IgG with prozone effect [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Sometimes high titer antibody can be associated with low levels of detection (low mean fluorescence intensity, MFI, for the Luminex HLA bead assay), a phenomenon often referred to as the "prozone" effect. This term is intended to report those antibodies that were not detected at significant level with original sample, but became detectable after dilution or assay treatment. Some laboratories refer to these "prozone antigens observed", meaning those antigens for which the patient's antibody exhibited prozone effect.
Source: Regenstrief LOINC
Part Descriptions
LP417655-0 HLA-DP & DQ & DR (class II) Ab.IgG with prozone effect
HLA antibodies showing the prozone effect represent antibody specificities against HLA antigens that were not apparent in undiluted patient specimen, but became apparent after dilution. This so called prozone effect has been attributed to a number of putative mechanisms, including complement factor, antibody agglutination or competing IgM. Prozone effect can often be reversed with serum dilution or treatment with heat, EDTA, or DTT.
Source: Regenstrief LOINC
LP417655-0 HLA-DP & DQ & DR (class II) Ab.IgG with prozone effect
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-DP & DQ & DR (class II) Ab.IgG with prozone effect
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA classII Ab.IgG prozone SerPl FC
- Display Name
- HLA-DP & DQ & DR (class II) Ab.IgG with prozone effect FC Nom
- Consumer Name Alpha Get Info
- HLA-DP & DQ & DR (class II) Ab.IgG with prozone effect, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL3602-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DP1 | LA23895-8 | ||
| Anti-DP2 | LA23894-1 | ||
| Anti-DP3 | LA23897-4 | ||
| Anti-DP4 | LA23896-6 | ||
| Anti-DP5 | LA23898-2 | ||
| Anti-DP6 | LA23899-0 | ||
| Anti-DQ1 | LA23909-7 | ||
| Anti-DQ2 | LA23906-3 | ||
| Anti-DQ3 | LA23907-1 | ||
| Anti-DQ4 | LA23908-9 | ||
| Anti-DQ5(1) | LA23903-0 | ||
| Anti-DQ6(1) | LA23902-2 | ||
| Anti-DQ7(3) | LA23904-8 | ||
| Anti-DQ8(3) | LA23905-5 | ||
| Anti-DR1 | LA23910-5 | ||
| Anti-DR3 | LA23914-7 | ||
| Anti-DR4 | LA23915-4 | ||
| Anti-DR6 | LA23922-0 | ||
| Anti-DR7 | LA23916-2 | ||
| Anti-DR8 | LA23917-0 | ||
| Anti-DR10 | LA23918-8 | ||
| Anti-DR11(5) | LA23919-6 | ||
| Anti-DR12(5) | LA23920-4 | ||
| Anti-DR13(6) | LA23921-2 | ||
| Anti-DR14(6) | LA23923-8 | ||
| Anti-DR15(2) | LA23924-6 | ||
| Anti-DR16(2) | LA23925-3 | ||
| Anti-DR17(3) | LA23912-1 | ||
| Anti-DR18(3) | LA23913-9 | ||
| Anti-DR51 | LA23927-9 | ||
| Anti-DR52 | LA23926-1 | ||
| Anti-DR53 | LA23928-7 | ||
| Anti-DR103 | LA23911-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DP, DQ, DR (CLASE II) con efecto prozona por Ac IgG: |
| es-MX | Spanish (Mexico) | HLA-DP & DQ & DR (clase II) Ab.IgG con efecto prozona: |
| fr-FR | French (France) | HLA-DP et DQ et DR (classe II) anticorps IgG avec effet prozone: |
| it-IT | Italian (Italy) | HLA-DP & DQ & DR (classe II) Ab.IgG con effetto prozona: Synonyms: Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-DP e DQ e DR (classe II) HLA-DP e DQ e DR (classe II) Ab.IgG con effetto prozona Plasma Presenza o Identità Pressione differenziale Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DP & DQ & DR (klasse II) As.IgG met prozoneffect: |
| pl-PL | Polish (Poland) | HLA-DP & DQ & DR (klasa II) Ab.IgG z efektem prozony: Synonyms: IgG Przeciwciała IgG do HLA-DP, DQ i DR (klasa II) Przeciwciała IgG do HLA-DP, DQ i DR (klasa II) z efektem prozony |
| zh-CN | Chinese (China) | HLA-DP 与 DQ 与 DR (II 类) 抗体.IgG 伴前带效应: Synonyms: HLA II 类; |
94439-7 HLA-DRB1 IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Some high specificity assays,such as the Luminex single bead system, detect epitopes at a detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serological type, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-DRB1 antibody specificity.
Source: Regenstrief LOINC
Part Descriptions
LP36435-3 HLA-DRB1
Major histocompatibility complex, class II, DR beta 1, also known as HLA-DRB1, is a human gene.[1] DRB1 encodes the most prevalent beta subunit of HLA-DR.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- HLA-DRB1 Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-DRB1 IgG SerPl FC
- Display Name
- HLA-DRB1 IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-DRB1 IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5529-4
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DR1 (DRB1*01:02) | LA30727-4 | ||
| Anti-DR4 (DRB1*04:01) | LA30728-2 | ||
| Anti-DR4 (DRB1*04:02) | LA30729-0 | ||
| Anti-DR7 (DRB1*07:01) | LA30730-8 | ||
| Anti-DR9 (DRB1*09:01) | LA30731-6 | ||
| Anti-DR10 (DRB1*10:01) | LA30732-4 | ||
| Anti-DR15 (DRB1*15:01) | LA30733-2 | ||
| Anti-DR15 (DRB1*15:02) | LA30734-0 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DRB1 IgG: |
| es-MX | Spanish (Mexico) | HLA-DRB1 Ab.IgG: |
| fr-FR | French (France) | HLA-DRB1 anticorps IgG: |
| fr-CA | French (Canada) | HLA-DRB1, IgG: |
| fr-BE | French (Belgium) | HLA-DRB1 Anticorps. IgG: Synonyms: Anticorps |
| it-IT | Italian (Italy) | HLA-DRB1 Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DRB1 As.IgG: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | HLA-DRB1 Ат.IgG: Synonyms: Антитело Номинальный; |
| tr-TR | Turkish (Turkey) | HLA-DRB1 Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi |
| zh-CN | Chinese (China) | HLA-DRB1 抗体.IgG: Synonyms: Ab.IgG; |
94438-9 HLA-DRB3 and HLA-DRB4 and HLA DRB5 IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
High specificity assays,such as the Luminex single bead system, can detect HLA epitopes at a detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serologic type, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-DRB3, 4, and 5 antibody specificity.
Source: Regenstrief LOINC
Part Descriptions
LP417658-4 HLA-DRB3 & HLA-DRB4 & HLA DRB5
HLA DRB3, 4 and 5 belong to the HLA class II beta chain paralogues that formed as a evolutionary duplication of HLA-DRB1. The HLA-DRB5, HLA-DRB3, and HLA-DRB4 genes encode for the serological antigens DR51, DR52 and DR53, respectively. While they exhibit fewer polymorphisms than HLA-DRB1, show moderate variability and are only present in a subset of individuals, antibody testing is routinely done as they are thought to play a role in transplant rejection PMID: 30192820
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-DRB3 & HLA-DRB4 & HLA DRB5 Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-DRB3 + 4 + 5 IgG SerPl FC
- Display Name
- HLA-DRB3 & HLA-DRB4 & HLA DRB5 IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-DRB3 & HLA-DRB4 & HLA DRB5 IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5528-6
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DR52 (DRB3*01:01) | LA30720-9 | ||
| Anti-DR52 (DRB3*02:02) | LA30721-7 | ||
| Anti-DR52 (DRB3*03:01) | LA30722-5 | ||
| Anti-DR53 (DRB4*01:01) | LA30723-3 | ||
| Anti-DR53 (DRB4*01:03) | LA30724-1 | ||
| Anti-DR51 (DRB5*01:01) | LA30725-8 | ||
| Anti-DR51 (DRB5*02:02) | LA30726-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DRB3, HLA-DRB4, HLA DRB5 IgG: |
| es-MX | Spanish (Mexico) | IgG HLA-DRB3 y HLA-DRB4 y HLA DRB5: |
| fr-FR | French (France) | HLA-DRB3 et HLA-DRB4 et HLA DRB5 anticorps IgG: |
| it-IT | Italian (Italy) | HLA-DRB3 & HLA-DRB4 & HLA DRB5 Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi HLA-DRB3 e HLA-DRB4 e HLA DRB5 Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DRB3 & HLA-DRB4 & HLA DRB5 As.IgG: Synonyms: antistof; |
| zh-CN | Chinese (China) | HLA-DRB3 & HLA-DRB4 & HLA DRB5 抗体.IgG: Synonyms: Ab.IgG; |
94437-1 HLA-DQA1 IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Some high specificity assays,such as the Luminex single bead system, detect epitopes at a detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serological type, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-DQA1 antibody specificity.
Source: Regenstrief LOINC
Part Descriptions
LP36770-3 HLA-DQA1
Major histocompatibility complex, class II, DQ alpha 1, also known as HLA-DQA1, is a human gene. The protein encoded by this gene is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor impportant for presenting antigens and triggering a humural immunity. The gene is highly polymorphic (as are other HLA genes), and allele type can correlate with various diseases (such as celiac). Antibodies formed in a transplant recipient to donor alleles can contribute to prediction of graft rejection.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-DQA1 Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-DQA1 IgG SerPl FC
- Display Name
- HLA-DQA1 IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-DQA1 IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5530-2
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DQ2 (DQA1*02:01, DQB1*02:01) | LA30735-7 | ||
| Anti-DQ2 (DQA1*03:01, DQB1*02:01) | LA30736-5 | ||
| Anti-DQ4 (DQA1*02:01, DQB1*04:01) | LA30737-3 | ||
| Anti-DQ4 (DQA1*03:03, DQB1*04:01) | LA30738-1 | ||
| Anti-DQ5 (DQA1*01:01, DQB1*05:01) | LA30739-9 | ||
| Anti-DQ7 (DQA1*05:03, DQB1*03:01) | LA30740-7 | ||
| Anti-DQ7 (DQA1*05:05, DQB1*03:01) | LA30741-5 | ||
| Anti-DQ9 (DQA1*02:01, DQB1*03:03) | LA30742-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DQA1 IgG: |
| es-MX | Spanish (Mexico) | HLA-DQA1 Ab.IgG: |
| fr-FR | French (France) | HLA-DQA1 anticorps IgG: |
| fr-CA | French (Canada) | HLA-DQA1, IgG: |
| fr-BE | French (Belgium) | HLA-DQA1 Anticorps. IgG: Synonyms: Anticorps |
| it-IT | Italian (Italy) | HLA-DQA1 Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DQA1 As.IgG: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | HLA-DQA1 Ат.IgG: Synonyms: Антитело Номинальный; |
| tr-TR | Turkish (Turkey) | HLA-DQA1 Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi |
| zh-CN | Chinese (China) | HLA-DQA1 抗体.IgG: Synonyms: Ab.IgG; |
94436-3 HLA-DQB1 IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Some high specificity assays,such as the Luminex single bead system, detect epitopes at a detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serological type, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-DQB1 antibody specificity.
Source: Regenstrief LOINC
Part Descriptions
LP36436-1 HLA-DQB1
Major histocompatibility complex, class II, DQ beta 1, also known as HLA-DQB1, is a human gene. The protein encoded by this gene is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor essential to the function of the immune system.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- HLA-DQB1 Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-DQB1 IgG SerPl FC
- Display Name
- HLA-DQB1 IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-DQB1 IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5530-2
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DQ2 (DQA1*02:01, DQB1*02:01) | LA30735-7 | ||
| Anti-DQ2 (DQA1*03:01, DQB1*02:01) | LA30736-5 | ||
| Anti-DQ4 (DQA1*02:01, DQB1*04:01) | LA30737-3 | ||
| Anti-DQ4 (DQA1*03:03, DQB1*04:01) | LA30738-1 | ||
| Anti-DQ5 (DQA1*01:01, DQB1*05:01) | LA30739-9 | ||
| Anti-DQ7 (DQA1*05:03, DQB1*03:01) | LA30740-7 | ||
| Anti-DQ7 (DQA1*05:05, DQB1*03:01) | LA30741-5 | ||
| Anti-DQ9 (DQA1*02:01, DQB1*03:03) | LA30742-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DQB1 IgG: |
| es-MX | Spanish (Mexico) | HLA-DQB1 Ab.IgG: |
| fr-FR | French (France) | HLA-DQB1 anticorps IgG: |
| fr-CA | French (Canada) | HLA-DQB1, IgG: |
| fr-BE | French (Belgium) | HLA-DQB1 Anticorps. IgG: Synonyms: Anticorps |
| it-IT | Italian (Italy) | HLA-DQB1 Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DQB1 As.IgG: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | HLA-DQB1 Ат.IgG: Synonyms: Антитело Номинальный; |
| tr-TR | Turkish (Turkey) | HLA-DQB1 Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi |
| zh-CN | Chinese (China) | HLA-DQB1 抗体.IgG: Synonyms: Ab.IgG; |
94435-5 HLA-DPA1 IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Some high specificity assays,such as the Luminex single bead system, detect epitopes at a detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serological type, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-DPA1 antibody specificity.
Source: Regenstrief LOINC
Part Descriptions
LP99668-3 HLA-DPA1
Major histocompatibility complex, class II, DP alpha 1, also known as HLA-DPA1, is a human gene.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- HLA-DPA1 Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-DPA1 IgG SerPl FC
- Display Name
- HLA-DPA1 IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-DPA1 IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5531-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DP1 (DPA1*01:03, DPB1*01:01) | LA30743-1 | ||
| Anti-DP1 (DPA1*02:01, DPB1*01:01) | LA30744-9 | ||
| Anti-DP3 (DPA1*01:05, DPB1*03:01) | LA30745-6 | ||
| Anti-DP5 (DPA1*02:01, DPB1*05:01) | LA30746-4 | ||
| Anti-DP28 (DPA1*01:03, DPB1*28:01) | LA30747-2 | ||
| Anti-DP13 (DPA1*02:01, DPB1*13:01) | LA30748-0 | ||
| Anti-DP14 (DPA1*02:01, DPB1*14:01) | LA30749-8 | ||
| Anti-DP15 (DPA1*02:01, DPB1*15:01) | LA30750-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DPA1 IgG: |
| es-MX | Spanish (Mexico) | HLA-DPA1 Ab.IgG: |
| fr-FR | French (France) | HLA-DPA1 anticorps IgG: |
| fr-BE | French (Belgium) | HLA-DPA1 Anticorps. IgG: Synonyms: Anticorps |
| fr-CA | French (Canada) | HLA-DPA1, IgG: |
| it-IT | Italian (Italy) | HLA-DPA1 Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DPA1 As.IgG: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | HLA-DPA1 Ат.IgG: Synonyms: Антитело Номинальный; |
| tr-TR | Turkish (Turkey) | HLA-DPA1 Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi |
| zh-CN | Chinese (China) | HLA-DPA1 抗体.IgG: Synonyms: Ab.IgG; |
94434-8 HLA-DPB1 IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Term Description
Some high specificity assays,such as the Luminex single bead system, detect epitopes at a detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serological type, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-DPB1 antibody specificity.
Source: Regenstrief LOINC
Part Descriptions
LP99667-5 HLA-DPB1
HLA class II histocompatibility antigen, DP(W2) beta chain is a protein that in humans is encoded by the HLA-DPB1 gene
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- HLA-DPB1 Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-DPB1 IgG SerPl FC
- Display Name
- HLA-DPB1 IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-DPB1 IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Example Answer List LL5531-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-DP1 (DPA1*01:03, DPB1*01:01) | LA30743-1 | ||
| Anti-DP1 (DPA1*02:01, DPB1*01:01) | LA30744-9 | ||
| Anti-DP3 (DPA1*01:05, DPB1*03:01) | LA30745-6 | ||
| Anti-DP5 (DPA1*02:01, DPB1*05:01) | LA30746-4 | ||
| Anti-DP28 (DPA1*01:03, DPB1*28:01) | LA30747-2 | ||
| Anti-DP13 (DPA1*02:01, DPB1*13:01) | LA30748-0 | ||
| Anti-DP14 (DPA1*02:01, DPB1*14:01) | LA30749-8 | ||
| Anti-DP15 (DPA1*02:01, DPB1*15:01) | LA30750-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DPB1 IgG: |
| es-MX | Spanish (Mexico) | HLA-DPB1 Ab.IgG: |
| fr-CA | French (Canada) | HLA-DPB1, IgG: |
| fr-FR | French (France) | HLA-DPB1 anticorps IgG: |
| fr-BE | French (Belgium) | HLA-DPB1 Anticorps. IgG: Synonyms: Anticorps |
| it-IT | Italian (Italy) | HLA-DPB1 Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-DPB1 As.IgG: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | HLA-DPB1 Ат.IgG: Synonyms: Антитело Номинальный; |
| tr-TR | Turkish (Turkey) | HLA-DPB1 Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi |
| zh-CN | Chinese (China) | HLA-DPB1 抗体.IgG: Synonyms: Ab.IgG; |
72323-9 HLA-DP+DQ+DR (class II) IgG Ab [Presence] in Serum by Flow cytometry (FC)
Term Description
IgG antibodies to HLA class II antigens (DP, DQ, and DR) can be detected by flow cytometry in serum of pre and post-transplant organ recipients. A positive result is an indication of a sensitization to HLA antigens. This code is based on, but not exclusive to, the submitter's test kit, One Lambda's FlowPRA Screening Test, which uses beads coated with common and rare purified HLA Class I or II antigens.
Source: Regenstrief LOINC
Part Descriptions
LP156721-5 HLA-DP+DQ+DR Ab.IgG
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-DP+DQ+DR Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-DP+DQ+DR IgG Ser Ql FC
- Display Name
- HLA-DP+DQ+DR (class II) IgG FC Ql (S)
- Consumer Name Alpha Get Info
- HLA-DP+DQ+DR (class II) IgG antibody, Blood
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 72905-3 | Neutrophil Ab and HLA Ab screen panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-DP+DQ6DR IgG: |
| es-MX | Spanish (Mexico) | HLA-DP + DQ + DR Ab.IgG: |
| et-EE | Estonian (Estonia) | HLA-DP+DQ+DR antikehad.IgG: Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Seerum |
| fr-CA | French (Canada) | HLA-DP+DQ+DR, IgG: |
| fr-FR | French (France) | HLA-DP+DQ+DR anticorps IgG: |
| fr-BE | French (Belgium) | HLA-DP+DQ+DR Anticorps. IgG: Synonyms: Anticorps |
| it-IT | Italian (Italy) | HLA-DP+DQ+DR Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Presenza o Soglia Pressione differenziale Punto nel tempo (episodio) Siero |
| nl-NL | Dutch (Netherlands) | HLA-DP+DQ+DR As.IgG: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | HLA-DP+DQ+DR Ac.IgG: |
| ru-RU | Russian (Russian Federation) | HLA-DP+DQ+DR Ат.IgG: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | HLA-DP+DQ+DR Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi Mevcut |
| zh-CN | Chinese (China) | HLA-DP+DQ+DR 抗体.IgG: Synonyms: Ab.IgG; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
8100-0 Specimen preparation [Type]
Fully-Specified Name
- Component
- Specimen preparation
- Property
- Type
- Time
- Pt
- System
- XXX
- Scale
- Nom
- Method
- *
Additional Names
- Short Name
- Specimen preparation
- Display Name
- Specimen preparation Nom (Specimen)
- Consumer Name Alpha Get Info
- Specimen preparation, Specimen
Basic Attributes
- Class
- SPEC
- Type
- Laboratory
- First Released
- Version 1.0h(2)
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 2431
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 96046-8 | B and T cell crossmatch panel - Patient serum and Donor blood by Flow cytometry (FC) |
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-AR | Spanish (Argentina) | preparación del espécimen: |
| es-ES | Spanish (Spain) | Preparación de la muestra: |
| es-MX | Spanish (Mexico) | Preparación de espécimen: |
| fr-CA | French (Canada) | Préparation de l'échantillon: |
| fr-FR | French (France) | Préparation du prélèvement: |
| fr-BE | French (Belgium) | Préparation de l'échantillon: |
| it-IT | Italian (Italy) | Campione, preparazione: Synonyms: Caratteristiche campione Preparazione del campione Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | monsterpreparatie: |
| pl-PL | Polish (Poland) | Przygotowanie próbki: |
| pt-BR | Portuguese (Brazil) | Preparação da amostra: Synonyms: Typ; |
| ru-RU | Russian (Russian Federation) | Образец подготовка: Synonyms: Номинальный; |
| zh-CN | Chinese (China) | 标本制备: Synonyms: 不明的; |
94431-4 Dilution factor [Titer] in Serum or Plasma
Fully-Specified Name
- Component
- Dilution factor
- Property
- Titr
- Time
- Pt
- System
- Ser/Plas
- Scale
- SemiQn
- Method
Additional Names
- Short Name
- Dilution factor Titr SerPl
- Display Name
- Dilution factor [Titer]
- Consumer Name Alpha Get Info
- Dilution factor, Blood
Basic Attributes
- Class
- MISC
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94440-5 | HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Factor de dilución: Synonyms: Semicuantitativo |
| es-MX | Spanish (Mexico) | Factor de dilución: |
| fr-FR | French (France) | Facteur de dilution: |
| it-IT | Italian (Italy) | Diluizione, fattore: Synonyms: Fattore di diluizione Miscellanea Plasma Punto nel tempo (episodio) Siero Siero o Plasma Titolo |
| nl-NL | Dutch (Netherlands) | verdunningsfactor: |
| zh-CN | Chinese (China) | 稀释倍数: Synonyms: 因素 效价; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |