94443-9

HLA-C IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)

Active

Term Description

This term will report antibodies detected against specific HLA antigens at the serologic type level. However, some high specificity assays,such as the Luminex single bead system, can detect epitopes at a more detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serotype, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-C antibody specificity.

Part Description

LP193954-7 HLA-C Ab.IgG
HLA-C, along with HLA-B and HLA-A, is a class I major histocompatibility complex (MHC) receptor, which are keys to antigen presentation in the immune system. It is coded by the HLA-C gene located on human chromosome 6. The class I molecules are heterodimers composed of one alpha subunit (the product of the class I gene) and a beta subunit, beta2 microglobulin. The high variability of this class of molecules is likely key to protecting the humans from pathogens, as it is more likely that a subset of the population will be highly immune to any given pathogen, and this diversity is reflected in the hundreds to thousands of possible alleles. However, the variability in HLA is also the reason for transplant rejection, and the detection of HLA antibodies in the transplant recipient has become a critical pre-transplant assessment. https://www.genecards.org/cgi-bin/carddisp.pl?gene=HLA-C Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: HLA-C Ab.IgG:Prid:Pt:Ser/Plas:Nom:Flow cytometry
Long Common Name: HLA-C IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Short Name: HLA-C IgG SerPl FC
Display Name: HLA-C IgG FC Nom
Consumer Name Alpha Get Info: HLA-C IgG antibody, Blood

Part Model Get Info

Component
HLA-C Ab.IgG
LP193954-7
- Analyte
  HLA-C Ab.IgG
  LP193954-7
  - Component Numerator
    HLA-C Ab.IgG
    LP193954-7
    - Component Numerator Core
      HLA-C
      LP18324-1
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Prid
LP6850-4
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Nom
LP7750-5
Method
Flow cytometry
LP6274-7

Example Answer List: LL5527-8

Source: NCBI PubMed

Answer	Code	Score	Answer ID
Anti-Cw1 (C*01:02)			LA30712-6
Anti-Cw10 (C*03:02)			LA30713-4
Anti-Cw10 (C*03:04)			LA30714-2
Anti-Cw4 (C*04:01)			LA30715-9
Anti-Cw5 (C*05:01)			LA30716-7
Anti-Cw12 (C*12:03)			LA30717-5
Anti-Cw15 (C*15:02)			LA30718-3
Anti-Cw16 (C*16:01)			LA30719-1

Basic Attributes

Class: HLA
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.68 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
94428-0	HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC)
94446-2	HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC)

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	HLA-C IgG:Přítomnost nebo identita:Časový bod:Sérum/plazma:Nominální:Průtoková cytometrie
el-GR	Greek (Greece)	Ανθρώπινα λευκοκυτταρικά αντιγόνα-C Αντισώματα IgG:Prid:Pt:Ορός/Πλάσμα:Nom:Κυτταρομετρία ροής Synonyms: C Nom Prid Pt Ανθρώπινα λευκοκυτταρικά αντιγόνα Ανθρώπινα λευκοκυτταρικά αντιγόνα-C Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Κυτταρομετρία ροής Ορός Ορός/Πλάσμα Πλάσμα
es-ES	Spanish (Spain)	HLA-C IgG:Presencia o identidad:Punto temporal:Suero o Plasma:Nom:Citometria de flujo (FC)
es-MX	Spanish (Mexico)	HLA-C Ab.IgG:Presencia o identidad:Punto temporal:Suero o Plasma:Nominal:Citometría de flujo (FC)
fr-FR	French (France)	HLA-C Ac IgG:Identification:Ponctuel:Sérum/Plasma:Résultat nominal:Cytométrie de flux
fr-BE	French (Belgium)	HLA-C Anticorps. IgG:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Cytométrie de flux Synonyms: Anticorps
fr-CA	French (Canada)	HLA-C, IgG:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Cytométrie de flux
it-IT	Italian (Italy)	HLA-C Ab.IgG:Prid:Pt:Siero/Plasma:Nom:Citometria a flusso Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	HLA-C As.IgG:identificator:moment:serum of plasma:nominaal:flowcytometrie Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	HLA-C Ab.IgG:obecność lub identyfikacja:punkt w czasie:surowica lub osocze:skala nominalna:cytometria przepływowa (FC) Synonyms: IgG Przeciwciała do antygenu C przeciwciała IgG Przeciwciała IgG do HLA-C wynik kategorialny
ru-RU	Russian (Russian Federation)	HLA-C Ат.IgG:ПрИд:ТчкВрм:Сыв/Плаз:Ном:Проточная цитометрия Synonyms: Антитело Номинальный;Именной Плазма Присутствие или Идентификация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	HLA-C Ab.IgG:MevcKimlik:Zmlı:Ser/Plaz:Snf:Akış sitometri Synonyms: Ak Ak.IgG Akış hücremetresi
zh-CN	Chinese (China)	HLA-C 抗体.IgG:存在与否或特征标识:时间点:血清/血浆:名义型:流式细胞测量术 Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 C 型;丙;丙型 C 型抗体 HLA 抗原;人类白细胞抗原;human leukocyte antigen 人白细胞抗原人类白细胞抗原人类白细胞抗原（Human Leukocyte Antigen，HLA）免疫球蛋白 G 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答动态存在;存在与否;特征标识;身份;身份标识时刻;随机;随意;瞬间流流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计白细胞抗原血清或血浆

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.