94443-9
HLA-C IgG Ab [Identifier] in Serum or Plasma by Flow cytometry (FC)
Active
Term Description
This term will report antibodies detected against specific HLA antigens at the serologic type level. However, some high specificity assays,such as the Luminex single bead system, can detect epitopes at a more detailed molecular allele-equivalent level. Therefore, many laboratories using this assay will report, along with the serotype, the molecular type, and also the mean fluorescence intensity (MFI) in a single answer. This term is intended to cover the existing reporting formats for HLA-C antibody specificity.
Source: Regenstrief LOINC
Part Description
LP193954-7 HLA-C Ab.IgG
HLA-C, along with HLA-B and HLA-A, is a class I major histocompatibility complex (MHC) receptor, which are keys to antigen presentation in the immune system. It is coded by the HLA-C gene located on human chromosome 6. The class I molecules are heterodimers composed of one alpha subunit (the product of the class I gene) and a beta subunit, beta2 microglobulin. The high variability of this class of molecules is likely key to protecting the humans from pathogens, as it is more likely that a subset of the population will be highly immune to any given pathogen, and this diversity is reflected in the hundreds to thousands of possible alleles. However, the variability in HLA is also the reason for transplant rejection, and the detection of HLA antibodies in the transplant recipient has become a critical pre-transplant assessment. [https://www.genecards.org/cgi-bin/carddisp.pl?gene=HLA-C]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-C Ab.IgG
- Property
- Prid
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nom
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-C IgG SerPl FC
- Display Name
- HLA-C IgG FC Nom
- Consumer Name Alpha Get Info
- HLA-C IgG antibody, Blood
Example Answer List: LL5527-8
Source: NCBI PubMed| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Anti-Cw1 (C*01:02) | LA30712-6 | ||
| Anti-Cw10 (C*03:02) | LA30713-4 | ||
| Anti-Cw10 (C*03:04) | LA30714-2 | ||
| Anti-Cw4 (C*04:01) | LA30715-9 | ||
| Anti-Cw5 (C*05:01) | LA30716-7 | ||
| Anti-Cw12 (C*12:03) | LA30717-5 | ||
| Anti-Cw15 (C*15:02) | LA30718-3 | ||
| Anti-Cw16 (C*16:01) | LA30719-1 |
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-C IgG: |
| es-MX | Spanish (Mexico) | HLA-C Ab.IgG: |
| fr-FR | French (France) | HLA-C anticorps IgG: |
| fr-BE | French (Belgium) | HLA-C Anticorps. IgG: Synonyms: Anticorps |
| fr-CA | French (Canada) | HLA-C , IgG: |
| it-IT | Italian (Italy) | HLA-C Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | HLA-C As.IgG: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | HLA-C Ат.IgG: Synonyms: Антитело Номинальный; |
| tr-TR | Turkish (Turkey) | HLA-C Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi |
| zh-CN | Chinese (China) | HLA-C 抗体.IgG: Synonyms: Ab.IgG; |
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