94689-7
CD20 cells/Cells.CD19 in Blood
Active
Part Description
LP17751-6 Cells.CD20
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein on the surface of all B-cells starting at the pro-B phase (CD45R+, CD117+) and increases in concentration until maturity. In humans CD20 is encoded by the MS4A1 gene. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells. CD20 is the target of the monoclonal antibodies (mAb) rituximab, Ibritumomab tiuxetan, and tositumomab, that are active agents in the treatment of all B cell lymphomas and leukemias. The anti-CD20 mAB Ofatumumab (Genmab) was approved by FDA in Oct 2009 for Chronic lymphocytic leukemia.
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Source: Wikipedia
, CD20
Fully-Specified Name
- Component
- Cells.CD20/Cells.CD19
- Property
- NFr
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- CD20 cells/Cells.CD19 in Blood
- Short Name
- CD20 Cells/Cells.CD19 NFr Bld
- Display Name
- CD20 cells/Cells.CD19 (Bld)
- Consumer Name Alpha Get Info
- CD20 cells/Cells.CD19, Blood
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.79 (NAM)
- Change Reason
- Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 5306
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-MX | Spanish (Mexico) | Células CD20 / 100 células CD19: |
es-ES | Spanish (Spain) | Células CD20+/Porcentaje de células CD19: Synonyms: Cuantitativo |
fr-FR | French (France) | CD20/100 cellules CD19: |
it-IT | Italian (Italy) | Cellule.CD20/Cellule.CD19: Synonyms: Cellule CD19 Cellule CD20 Cellule.CD19 Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue |
nl-NL | Dutch (Netherlands) | cellen.CD20/100 cellen.CD19: |
uk-UA | Ukrainian (Ukraine) | Клітини.CD20/100 клітин.CD19: Synonyms: 100 CD19 cells; |
zh-CN | Chinese (China) | 细胞.CD20/细胞.CD19: Synonyms: B1; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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