94691-3
Dermatan sulfate, heparan sulfate, chondroitin-6-sulfate, keratan sulfate panel - Urine
Active
94692-1 Dermatan sulfate/Creatinine [Ratio] in Urine
Part Descriptions
LP15532-2 Dermatan sulfate
Dermatan sulfate is a derived disaccharide that accumulates in lysosomes, extracellular matrix, and body fluids of people with mucopolysaccharidoses (MPSs). MPSs are rare disorders caused by a deficiency of enzymes that break down glycosaminoglycans (GAGs). Symptoms of MPS vary due to which storage product accumulates and the level of enzymatic function or concentration that remains. Symptoms include musculoskeletal, airway, cardiac, and central nervous system disorders. Treatments include hematopoietic stem cell transplantation for the more critical forms of MPS and intravenous enzyme replacement therapy for the others. Treatment is most effective when it is initiated before irreversible tissue damage has occurred. Because MPS is so rare and the symptoms so variable, it is difficult to diagnose in its earliest stages. A solution to that problem is the development of newborn screening assays that can detect dermatan sulfate, though the levels in the dried blood spot samples do not appear to predict the severity of disease. The pattern of dermatan and heparan sulfate can help distinguish between the different MPSs. PMID: 23084433
Source: Regenstrief LOINC
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, Creatinine
Fully-Specified Name
- Component
- Dermatan sulfate/Creatinine
- Property
- Ratio
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Panel Name
- Short Name
- Dermatan Sulfate/Creat Ur-Rto
- Display Name
- Dermatan sulfate/Creatinine (U) [Ratio]
- Consumer Name Alpha Get Info
- Dermatan sulfate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94691-3 | Dermatan sulfate, heparan sulfate, chondroitin-6-sulfate, keratan sulfate panel - Urine |
| 105125-9 | Lysosomal storage disorders screen panel - Urine |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Θειική δερματάνη/Κρεατινίνη: Synonyms: Ratio Θειικά άλατα Θειική δερματάνη Κρεατινίνη |
| es-MX | Spanish (Mexico) | Dermatan sulfato / Creatinina: |
| es-ES | Spanish (Spain) | Dermatan sulfato/Creatinina: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Dermataansulfaat/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
| fr-FR | French (France) | Dermatane sulfate/créatinine: |
| fr-BE | French (Belgium) | Dermatane-sulfate/Créatinine: Synonyms: SO4 |
| fr-CA | French (Canada) | Dermatane sulfate/Créatinine: |
| it-IT | Italian (Italy) | Dermatan solfato/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | dermatansulfaat/creatinine: Synonyms: kreatinine |
| ru-RU | Russian (Russian Federation) | Дерматан сульфат/Креатинин: Synonyms: Дерматансульфат Количественный Коэффициент; |
| tr-TR | Turkish (Turkey) | Dermatan sülfat/Kreatinin: |
| zh-CN | Chinese (China) | 硫酸皮肤素/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| mg/mmol{creat} | Example UCUM Units |
94693-9 Heparan sulfate/Creatinine [Ratio] in Urine
Part Descriptions
LP15629-6 Heparan sulfate
Heparan sulfate is a derived disaccharide that accumulates in lysosomes, extracellular matrix, and body fluids of people with mucopolysaccharidoses (MPSs). MPSs are rare disorders caused by a deficiency of enzymes that break down glycosaminoglycans (GAGs). Symptoms of MPS vary due to which storage product accumulates and the level of enzymatic function or concentration that remains. Symptoms include musculoskeletal, airway, cardiac, and central nervous system disorders. Treatments include hematopoietic stem cell transplantation for the more critical forms of MPS and intravenous enzyme replacement therapy for the others. Treatment is most effective when it is initiated before irreversible tissue damage has occurred. Because MPS is so rare and the symptoms so variable, it is difficult to diagnose in its earliest stages. A solution to that problem is the development of newborn screening assays that can detect heparan sulfate, though the levels in the dried blood spot samples do not appear to predict the severity of disease. The pattern of dermatan and heparan sulfate can help distinguish between the different MPSs. PMID: 23084433
Source: Regenstrief LOINC
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, Creatinine
Fully-Specified Name
- Component
- Heparan sulfate/Creatinine
- Property
- Ratio
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Panel Name
- Short Name
- Heparan sulfate/Creat Ur-Rto
- Display Name
- Heparan sulfate/Creatinine (U) [Ratio]
- Consumer Name Alpha Get Info
- Heparan sulfate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 11724
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94691-3 | Dermatan sulfate, heparan sulfate, chondroitin-6-sulfate, keratan sulfate panel - Urine |
| 105125-9 | Lysosomal storage disorders screen panel - Urine |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Θειική ηπαράνη/Κρεατινίνη: Synonyms: Ratio Θειικά άλατα Θειική ηπαράνη Κρεατινίνη |
| es-MX | Spanish (Mexico) | Sulfato de Heparán / Creatinina: |
| es-ES | Spanish (Spain) | Heparán sulfato/Creatinina: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Heparaansulfaat/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
| fr-BE | French (Belgium) | Héparane-sulfate/Créatinine: Synonyms: SO4 |
| fr-FR | French (France) | Héparane sulfate/créatinine: |
| fr-CA | French (Canada) | Héparane sulfate/Créatinine: |
| it-IT | Italian (Italy) | Eparan solfato/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | heparansulfaat/creatinine: Synonyms: kreatinine |
| ru-RU | Russian (Russian Federation) | Гепаран сульфат/Креатинин: Synonyms: Гепарансульфат Количественный Коэффициент; |
| tr-TR | Turkish (Turkey) | Heparan sülfat/Kreatinin: |
| zh-CN | Chinese (China) | 硫酸类肝素/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| mg/mmol{creat} | Example UCUM Units |
94690-5 Chondroitin-6-sulfate/Creatinine [Ratio] in Urine
Part Descriptions
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, Creatinine
Fully-Specified Name
- Component
- Chondroitin-6-sulfate/Creatinine
- Property
- Ratio
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Panel Name
- Short Name
- C6S/Creat Ur-Rto
- Display Name
- Chondroitin-6-sulfate/Creatinine (U) [Ratio]
- Consumer Name Alpha Get Info
- Chondroitin-6-sulfate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68 (ADD)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94691-3 | Dermatan sulfate, heparan sulfate, chondroitin-6-sulfate, keratan sulfate panel - Urine |
| 105125-9 | Lysosomal storage disorders screen panel - Urine |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Θειική-6-χονδροϊτίνη/Κρεατινίνη: Synonyms: Ratio Θειικά άλατα Θειική-6-χονδροϊτίνη Κρεατινίνη |
| es-MX | Spanish (Mexico) | Condroitin-6-sulfato / Creatinina: |
| es-ES | Spanish (Spain) | Condroitin-6-sulfato/Creatinina: Synonyms: Cuantitativo |
| fr-FR | French (France) | Chondroïtine-6-sulfate/créatinine: |
| it-IT | Italian (Italy) | Condroitina-6-solfato/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | chondroïtine-6-sulfaat/creatinine: Synonyms: kreatinine |
| zh-CN | Chinese (China) | 软骨素-6-硫酸酯/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| mg/mmol{creat} | Example UCUM Units |
92806-9 Keratan sulfate/Creatinine [Ratio] in Urine
Part Descriptions
LP14490-4 Keratan sulfate
A sulfated mucopolysaccharide initially isolated from bovine cornea. At least two types are known. Type I, found mostly in the cornea, contains D-galactose and D-glucosamine-6-O-sulfate as the repeating unit; type II, found in skeletal tissues, contains D-galactose and D-galactosamine-6-O-sulfate as the repeating unit.
Source: National Library of Medicine, MeSH 2006
LP14490-4 Keratan sulfate
Keratan sulfate (KS) is one of the glycosaminoglycans found primarily in the cornea, nervous tissue, and bone. When the enzyme that breaks down KS is deficient or absent, KS accumulates in lysosomes which results in cell, tissue, and organ dysfunction. The lysosomal storage disorders are known as mucopolysaccharidoses (MPS) and can involve impaired enzymatic function that blocks the catabolism of any of the glycosaminoglycans, including dermatan sulfate, heparin sulfate, keratan sulfate, chondroitin sulfate, or hyaluronan. MPS due to the accumulation of any one or more glycosaminoglycans have many symptoms in common including a chronic or progressive course, multisystem involvement, organomegaly, dysostosis multiplex, abnormal facies, affected hearing, affected vision, affected airway, cardiovascular issues, profound mental retardation, and joint mobility difficulties. MPS can be diagnosed by testing for the deficient or absent enzyme. Enzyme replacement therapy is used to monitor treatment.[https://ommbid.mhmedical.com/content.aspx?bookid=971§ionid=62642135]
Source: Regenstrief LOINC
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, Creatinine
Fully-Specified Name
- Component
- Keratan sulfate/Creatinine
- Property
- Ratio
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Panel Name
- Short Name
- Keratan Sulfate/Creat Ur-Rto
- Display Name
- Keratan sulfate/Creatinine (U) [Ratio]
- Consumer Name Alpha Get Info
- Keratan sulfate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.66
- Last Updated
- Version 2.66 (ADD)
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94691-3 | Dermatan sulfate, heparan sulfate, chondroitin-6-sulfate, keratan sulfate panel - Urine |
| 105125-9 | Lysosomal storage disorders screen panel - Urine |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Θειική κερατάνη/Κρεατινίνη: Synonyms: Ratio Θειικά άλατα Θειική κερατάνη Κρεατινίνη |
| es-ES | Spanish (Spain) | Queratán sulfato/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Sulfato de queratán / Creatinina: |
| et-EE | Estonian (Estonia) | Kerataansulfaat/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
| fr-BE | French (Belgium) | Sulfate de kératane/Créatinine: Synonyms: SO4 |
| fr-CA | French (Canada) | Sulfate de kératane/Créatinine: |
| fr-FR | French (France) | Kératane sulfate/créatinine: |
| it-IT | Italian (Italy) | Cheratan solfato/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | keratansulfaat/creatinine: Synonyms: kreatinine |
| ru-RU | Russian (Russian Federation) | Кератансульфат/Креатинин: Synonyms: Количественный Коэффициент; |
| tr-TR | Turkish (Turkey) | Keratan sülfat/Kreatinin: |
| zh-CN | Chinese (China) | 硫酸角质素/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| mg/mmol{creat} | Example UCUM Units |