94818-2
Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence
Active
94706-9 CV2 IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP32718-6 CV2
CV2 (CRMP5) antibody binds to cytoplasm and cell processes of a subpopulation of oligodendrocytes in the white matter and targets 66 kDa protein known as CRMP5.
It is ofen found in association with small cell lung carcinoma. CV2 autoimmune response can also be found in cerebellar ataxia, encephalomyelitis, limbic encephalitis, sensory and sensorimotor neuropathy, autonomic neuropathy, and chorea. CV2 autoantibodies are also present in patients with rapidly progressive dementia, and are used to monitor treatment in some cases.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- CV2 Ab.IgG
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- CV2 IgG Titr CSF IF
- Display Name
- CV2 IgG IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- CV2 IgG antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG50993-1 | CV2 Ab.IgG| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | CV2 IgG: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | CV2 Ab.IgG: |
fr-FR | French (France) | CV2 anticorps IgG: |
fr-CA | French (Canada) | CV2, IgG: |
it-IT | Italian (Italy) | CV2 Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | CV2 As.IgG: Synonyms: antistof; |
zh-CN | Chinese (China) | CV2 抗体.IgG: Synonyms: Ab.IgG; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
14247-1 Purkinje cells Ab [Presence] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP17260-8 Purkinje cells
Purkinje cells (or Purkinje neurons) are a class of GABAergic neuron located in the cerebellar cortex.
These cells are some of the largest neurons in the human brain, with an intricately elaborate dendritic arbor, characterized by a large number of dendritic spines. Purkinje cells are found within the Purkinje layer in the cerebellum. Purkinje cells are aligned like dominos stacked one in front of the other. Their large dendritic arbors form nearly two dimensional layers through which parallel fibers from the deeper-layer granule cells pass. These parallel fibers make relatively weaker excitatory (glutamatergic) synapses to spines in the Purkinje cell dendrite, whereas climbing fibers originating from the inferior olivary nucleus in the medulla provide very powerful excitatory input to the proximal dendrites and cell soma.
In humans, Purkinje cells are affected in a variety of diseases ranging from toxic exposure (alcohol, lithium), to autoimmune diseases and to genetic mutations (spinocerebellar ataxias, Unverricht-Lundborg disease, autism) and neurodegenerative diseases that are not thought to have a known genetic basis (cerebellar type of multiple system atrophy, sporadic ataxias).
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Purkinje cells (Wikipedia)
LP17260-8 Purkinje cells
The output neurons of the cerebellar cortex.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Purkinje cells Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- Purkinje Cells Ab CSF Ql IF
- Display Name
- Purkinje cells Ab IF Ql (CSF)
- Consumer Name Alpha Get Info
- Purkinje cells antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 13603
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG2726-0 | Purkinje cells Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Yo-AK ql. IF /L |
es-AR | Spanish (Argentina) | [anticuerpo anti - ] células de Purkinje [Ac]: |
es-ES | Spanish (Spain) | Células de Purkinje Anticuerpos: |
es-MX | Spanish (Mexico) | Células de Purkinje Ab: |
et-EE | Estonian (Estonia) | Purkinje rakkude vastased antikehad: Synonyms: Järgarvuline Juhuslik Liikvor |
fr-CA | French (Canada) | Cellules de Purkinje, Ac: |
fr-FR | French (France) | YO anticorps: |
fr-BE | French (Belgium) | Cellules de Purkinje Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Cellule di Purkinje Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
ko-KR | Korean (Korea, Republic Of) | 심장전도근육 세포 항체: |
nl-NL | Dutch (Netherlands) | purkinjecellen As: Synonyms: antistof; |
pt-BR | Portuguese (Brazil) | Células Purkinje Ac: Synonyms: PCA; |
ru-RU | Russian (Russian Federation) | Пуркинье клетки Ат: Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Purkinje hücreleri Ab: Synonyms: Ak İmmünflorerans Mevcut |
uk-UA | Ukrainian (Ukraine) | Клітини Пуркіньє Антитіла: Synonyms: ABS; |
zh-CN | Chinese (China) | 浦肯雅细胞 抗体: Synonyms: Ab; |
14248-9 Purkinje cells Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP17260-8 Purkinje cells
Purkinje cells (or Purkinje neurons) are a class of GABAergic neuron located in the cerebellar cortex.
These cells are some of the largest neurons in the human brain, with an intricately elaborate dendritic arbor, characterized by a large number of dendritic spines. Purkinje cells are found within the Purkinje layer in the cerebellum. Purkinje cells are aligned like dominos stacked one in front of the other. Their large dendritic arbors form nearly two dimensional layers through which parallel fibers from the deeper-layer granule cells pass. These parallel fibers make relatively weaker excitatory (glutamatergic) synapses to spines in the Purkinje cell dendrite, whereas climbing fibers originating from the inferior olivary nucleus in the medulla provide very powerful excitatory input to the proximal dendrites and cell soma.
In humans, Purkinje cells are affected in a variety of diseases ranging from toxic exposure (alcohol, lithium), to autoimmune diseases and to genetic mutations (spinocerebellar ataxias, Unverricht-Lundborg disease, autism) and neurodegenerative diseases that are not thought to have a known genetic basis (cerebellar type of multiple system atrophy, sporadic ataxias).
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Purkinje cells (Wikipedia)
LP17260-8 Purkinje cells
The output neurons of the cerebellar cortex.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Purkinje cells Ab
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- Purkinje Cells Ab Titr CSF IF
- Display Name
- Purkinje cells Ab IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- Purkinje cells antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4828
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | [anticuerpo anti - ] células de Purkinje [Ac]: |
es-ES | Spanish (Spain) | Células de Purkinje Anticuerpos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Células de Purkinje Ab: |
fr-FR | French (France) | YO anticorps: |
fr-CA | French (Canada) | Cellules de Purkinje, Ac: |
it-IT | Italian (Italy) | Cellule di Purkinje Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
ko-KR | Korean (Korea, Republic Of) | 심장전도근육 세포 항체: |
nl-NL | Dutch (Netherlands) | purkinjecellen As: Synonyms: antistof; |
pt-BR | Portuguese (Brazil) | Células Purkinje Ac: Synonyms: PCA; |
uk-UA | Ukrainian (Ukraine) | Клітини Пуркіньє Антитіла: Synonyms: ABS; |
zh-CN | Chinese (China) | 浦肯雅细胞 抗体: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
56531-7 Amphiphysin Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP30843-4 Amphiphysin
Amphiphysin is a protein associated with the cytoplasmic surface of synaptic vesicles and is encoded by the AMPH gene. Patients with stiff man syndrome and breast cancer can be positive with autoantibodies against the amphiphysin protein.
Source: Regenstrief LOINC
LP37039-2 Amphiphysin Ab
Paraneoplastic syndromes (PNS) are diseases associated with remote effects of tumors, of which small-cell lung cancer (SCLC), ovarian cancer, breast cancer, thymoma, Hodgkin lymphoma, and testicular cancer are the most common. Stiff-person syndrome (SPS) is a rare neurological disorder characterized by stiffness of skeletal muscles with superimposed spasms, which can have an idiopathic or paraneoplastic component. First described in women with breast cancer and SPS, amphiphysin antibodies have been reported in patients with diverse paraneoplastic neurological disorders, and cancers. Amphiphysin antibodies are considered diagnosic for paraneoplastic neurologic syndromes and can direct the search for an occult tumor, recurrence of tumor, or second tumor.
Source: ARUP Laboratories
LP37039-2 Amphiphysin Ab
Amphiphysin is a brain-enriched protein normally found only within the membrane of synaptic vesicles in neural tissue. Antibodies against amphiphysin (128kDa) are directed against the protein amphiphysin, and their presence plays an important diagnostic role in paraneoplastic syndromes (e.g. Lambert Eaton myasthenia syndrome, encephalomyelitis with rigidity, cerebellar syndrome, sensory neuronopathy, opsoclonus myoclonus ataxia, and Stiff-man syndrome). Paraneoplastic syndromes are autoantibody-mediated neurologic disorders most commonly associated with cancers of the lung, breast, ovaries or lymphatic system.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Amphiphysin Ab
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- Amphiphysin Ab Titr CSF IF
- Display Name
- Amphiphysin Ab IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- Amphiphysin antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.29
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 12916
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG14304-6 | Amphiphysin Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Anfifisina Anticuerpos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Amphiphysin Ab: |
fr-FR | French (France) | Amphiphysine anticorps: |
fr-CA | French (Canada) | Amphiphysine, Ac: |
it-IT | Italian (Italy) | Amfifisina Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | amfifysine As: Synonyms: antistof; |
pt-BR | Portuguese (Brazil) | Anfifisina Ac: Synonyms: Dilution factor; |
zh-CN | Chinese (China) | 双载蛋白 抗体: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
90815-2 Amphiphysin Ab [Presence] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP30843-4 Amphiphysin
Amphiphysin is a protein associated with the cytoplasmic surface of synaptic vesicles and is encoded by the AMPH gene. Patients with stiff man syndrome and breast cancer can be positive with autoantibodies against the amphiphysin protein.
Source: Regenstrief LOINC
LP37039-2 Amphiphysin Ab
Paraneoplastic syndromes (PNS) are diseases associated with remote effects of tumors, of which small-cell lung cancer (SCLC), ovarian cancer, breast cancer, thymoma, Hodgkin lymphoma, and testicular cancer are the most common. Stiff-person syndrome (SPS) is a rare neurological disorder characterized by stiffness of skeletal muscles with superimposed spasms, which can have an idiopathic or paraneoplastic component. First described in women with breast cancer and SPS, amphiphysin antibodies have been reported in patients with diverse paraneoplastic neurological disorders, and cancers. Amphiphysin antibodies are considered diagnosic for paraneoplastic neurologic syndromes and can direct the search for an occult tumor, recurrence of tumor, or second tumor.
Source: ARUP Laboratories
LP37039-2 Amphiphysin Ab
Amphiphysin is a brain-enriched protein normally found only within the membrane of synaptic vesicles in neural tissue. Antibodies against amphiphysin (128kDa) are directed against the protein amphiphysin, and their presence plays an important diagnostic role in paraneoplastic syndromes (e.g. Lambert Eaton myasthenia syndrome, encephalomyelitis with rigidity, cerebellar syndrome, sensory neuronopathy, opsoclonus myoclonus ataxia, and Stiff-man syndrome). Paraneoplastic syndromes are autoantibody-mediated neurologic disorders most commonly associated with cancers of the lung, breast, ovaries or lymphatic system.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Amphiphysin Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- Amphiphysin Ab CSF Ql IF
- Display Name
- Amphiphysin Ab IF Ql (CSF)
- Consumer Name Alpha Get Info
- Amphiphysin antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Example Answer List LL2038-9
Answer | Code | Score | Answer ID |
---|---|---|---|
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG24036-2 | Amphiphysin Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Anfifisina Anticuerpos: |
es-MX | Spanish (Mexico) | Amphiphysin Ab: |
et-EE | Estonian (Estonia) | Amfifüsiin antikehad: Synonyms: Järgarvuline Juhuslik Liikvor |
fr-FR | French (France) | Amphiphysine anticorps: |
fr-BE | French (Belgium) | Amphiphysine Ac: Synonyms: Anticorps |
fr-CA | French (Canada) | Amphiphysine, Ac: |
it-IT | Italian (Italy) | Amfifisina Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | amfifysine As: Synonyms: antistof; |
ru-RU | Russian (Russian Federation) | Амфифизин Ат: Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Amfifizin Ab: Synonyms: Ak İmmünflorerans Mevcut |
zh-CN | Chinese (China) | 双载蛋白 抗体: Synonyms: Ab; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
94354-8 Amphiphysin IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP30843-4 Amphiphysin
Amphiphysin is a protein associated with the cytoplasmic surface of synaptic vesicles and is encoded by the AMPH gene. Patients with stiff man syndrome and breast cancer can be positive with autoantibodies against the amphiphysin protein.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Amphiphysin Ab.IgG
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- Amphiphysin IgG Titr CSF IF
- Display Name
- Amphiphysin IgG IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- Amphiphysin IgG antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94707-7 | Dementia autoimmune Ab panel - Cerebral spinal fluid |
94708-5 | Encephalopathy autoimmune Ab panel - Cerebral spinal fluid |
94709-3 | Epilepsy autoimmune Ab panel - Cerebral spinal fluid |
94712-7 | Movement disorder autoimmune Ab panel - Cerebral spinal fluid |
94353-0 | Myelopathy autoimmune Ab panel - Cerebral spinal fluid |
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Anfifisina IgG: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Anfifisina Ab.IgG: |
fr-CA | French (Canada) | Amphiphysine, IgG: |
fr-FR | French (France) | Amphiphysine anticorps IgG: |
it-IT | Italian (Italy) | Amfifisina Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | amfifysine As.IgG: Synonyms: antistof; |
zh-CN | Chinese (China) | 双载蛋白 抗体.IgG: Synonyms: Ab.IgG; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
90827-7 Glial nuclear type 1 Ab [Presence] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP71299-9 Glial nuclear type 1
Anti-glial nuclear antibody type 1 (AGNA-1) targets the Sox1 nuclear antigen found in Bergmann cells, a specialized glial cell type found in the cerebellar cortex. AGNA-1 antibodies are associated with paraneoplastic Lambert-Eaton myasthenic syndrome (LEMS) and paraneoplastic neuropathies associated with small cell lung cancer (SCLC). They have also been associated with non-paraneoplastic neuropathy, which may be an immune-mediated condition. PMID: 20701982
Source: Regenstrief LOINC, PMID: 20701982
Fully-Specified Name
- Component
- Glial nuclear type 1 Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- Glial nuc type 1 Ab CSF Ql IF
- Display Name
- Glial nuclear type 1 Ab IF Ql (CSF)
- Consumer Name Alpha Get Info
- Glial nuclear type 1 antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Example Answer List LL2038-9
Answer | Code | Score | Answer ID |
---|---|---|---|
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG51427-9 | Glial nuclear type 1 Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Gliales de tipo nuclear 1 Anticuerpos: |
es-MX | Spanish (Mexico) | Glial nuclear tipo 1 Ab: |
fr-FR | French (France) | Noyau cellule gliale type 1 anticorps: |
fr-BE | French (Belgium) | Glial nucléaire type 1 Ac: Synonyms: Anticorps |
fr-CA | French (Canada) | Gliale nucléaire de type 1, Ac: |
it-IT | Italian (Italy) | Gliali di tipo nucleare 1 Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | gliaal nucleair type 1 As: Synonyms: antistof; |
ru-RU | Russian (Russian Federation) | Глия ядро тип 1 Ат: Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Glial nukleer tip 1 Ab: Synonyms: Ak Çekirdek İmmünflorerans Mevcut |
zh-CN | Chinese (China) | 神经胶质细胞核 1 型 抗体: Synonyms: Ⅰ Ab; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
94355-5 Glial nuclear type 1 IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP71299-9 Glial nuclear type 1
Anti-glial nuclear antibody type 1 (AGNA-1) targets the Sox1 nuclear antigen found in Bergmann cells, a specialized glial cell type found in the cerebellar cortex. AGNA-1 antibodies are associated with paraneoplastic Lambert-Eaton myasthenic syndrome (LEMS) and paraneoplastic neuropathies associated with small cell lung cancer (SCLC). They have also been associated with non-paraneoplastic neuropathy, which may be an immune-mediated condition. PMID: 20701982
Source: Regenstrief LOINC, PMID: 20701982
Fully-Specified Name
- Component
- Glial nuclear type 1 Ab.IgG
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- Glial nuc type 1 IgG Titr CSF IF
- Display Name
- Glial nuclear type 1 IgG IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- Glial nuclear type 1 IgG antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94707-7 | Dementia autoimmune Ab panel - Cerebral spinal fluid |
94708-5 | Encephalopathy autoimmune Ab panel - Cerebral spinal fluid |
94709-3 | Epilepsy autoimmune Ab panel - Cerebral spinal fluid |
94712-7 | Movement disorder autoimmune Ab panel - Cerebral spinal fluid |
94353-0 | Myelopathy autoimmune Ab panel - Cerebral spinal fluid |
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Gliales de tipo nuclear 1 IgG: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Glial nuclear tipo 1 Ab.IgG: |
fr-CA | French (Canada) | Gliale nucléaire de type 1, IgG: |
fr-FR | French (France) | Noyau cellule gliale type 1 anticorps IgG: |
it-IT | Italian (Italy) | Gliali di tipo nucleare 1 Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | gliaal nucleair type 1 As.IgG: Synonyms: antistof; |
zh-CN | Chinese (China) | 神经胶质细胞核 1 型 抗体.IgG: Synonyms: Ⅰ Ab.IgG; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
24400-4 Neuronal nuclear type 1 Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP14163-7 Neuronal nuclear type 1
Type I anti-neuronal nuclear antibody (ANNA-1) is present in patients with paraneoplastic syndromes (paraneoplastic sensory neuropathy or paraneoplastic encephalomyelitis) most commonly associated with small-cell lung carcinoma (SCLC). ANNA-2 is present in patients with midbrain encephalitis, cerebellar ataxia, eye movement disorders (usually opsoclonus), and occasionally myelopathy. Neoplasms most often associated with ANNA-2 are breast carcinoma and SCLC. ANNA-1 and ANNA-2 may be detectable before the associated neoplasm is detectable.
Source: ARUP Laboratories, ANNA
Fully-Specified Name
- Component
- Neuronal nuclear type 1 Ab
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- Hu1 Ab Titr CSF IF
- Display Name
- Neuronal nuclear type 1 Ab IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- Neuronal nuclear type 1 antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0o
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4823
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG8743-9 | Neuronal nuclear type 1 Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | [anticuerpo] antinuclear neuronal tipo 1 [Ac]: |
es-ES | Spanish (Spain) | Anticuerpos Antineuronal nuclear tipo 1 Anticuerpos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Ab de tipo 1 nuclear neuronal: |
fr-CA | French (Canada) | Neuronal nucléaire de type 1, Ac: |
fr-FR | French (France) | Hu1 anticorps: |
it-IT | Italian (Italy) | Nucleare neuronale tipo 1 Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
ko-KR | Korean (Korea, Republic Of) | 신경 핵 1 형 항체: |
nl-NL | Dutch (Netherlands) | neuronaal nucleair type 1 As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Typ 1 neuronalny jądrowy Ab: Synonyms: Przeciwciała do antygenów jądrowych neuronów typu 1 Przeciwciała onkoneuronalne |
pt-BR | Portuguese (Brazil) | Neuronal nuclear tipo 1 Ac: Synonyms: Nuc; |
zh-CN | Chinese (China) | 神经元细胞核 1 型 抗体: Synonyms: Ⅰ Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
24401-2 Neuronal nuclear type 2 Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP14164-5 Neuronal nuclear type 2
Type I anti-neuronal nuclear antibody (ANNA-1) is present in patients with paraneoplastic syndromes (paraneoplastic sensory neuropathy or paraneoplastic encephalomyelitis) most commonly associated with small-cell lung carcinoma (SCLC). ANNA-2 is present in patients with midbrain encephalitis, cerebellar ataxia, eye movement disorders (usually opsoclonus), and occasionally myelopathy. Neoplasms most often associated with ANNA-2 are breast carcinoma and SCLC. ANNA-1 and ANNA-2 may be detectable before the associated neoplasm is detectable.
Source: ARUP Laboratories, ANNA
LP39195-0 Neuronal nuclear type 2 Ab
Neuronal nuclear antibody is a neuronal paraneoplastic antibody that has been associated with cerebellar degeneration in breast, small cell lung carcinoma and gynecological cancers.
Source: University of Birmingham, Neuronal antibodies
Fully-Specified Name
- Component
- Neuronal nuclear type 2 Ab
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- Hu2 Ab Titr CSF IF
- Display Name
- Neuronal nuclear type 2 Ab IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- Neuronal nuclear type 2 antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0o
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4826
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG8744-7 | Neuronal nuclear type 2 Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | [anticuerpo] antinuclear neuronal tipo 2 [Ac]: |
es-ES | Spanish (Spain) | Anticuerpos Antineuronal nuclear tipo 2 Anticuerpos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Nuclear neuronal tipo 2 Ab: |
fr-CA | French (Canada) | Neuronal nucléaire de type 2, Ac: |
fr-FR | French (France) | Hu2 anticorps: |
it-IT | Italian (Italy) | Nucleare neuronale tipo 2 Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
ko-KR | Korean (Korea, Republic Of) | 신경 핵 2 형 항체: |
nl-NL | Dutch (Netherlands) | neuronaal nucleair type 2 As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Typ 2 neuronalny jądrowy Ab: Synonyms: Przeciwciała do antygenów jądrowych komórek nerwowych typu 2 Przeciwciała onkoneuronalne |
pt-BR | Portuguese (Brazil) | Neuronal nuclear tipo 2 Ac: Synonyms: Nuc; |
zh-CN | Chinese (China) | 神经元细胞核 2 型 抗体: Synonyms: Ⅱ Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
44768-0 Neuronal nuclear type 1 Ab [Presence] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP14163-7 Neuronal nuclear type 1
Type I anti-neuronal nuclear antibody (ANNA-1) is present in patients with paraneoplastic syndromes (paraneoplastic sensory neuropathy or paraneoplastic encephalomyelitis) most commonly associated with small-cell lung carcinoma (SCLC). ANNA-2 is present in patients with midbrain encephalitis, cerebellar ataxia, eye movement disorders (usually opsoclonus), and occasionally myelopathy. Neoplasms most often associated with ANNA-2 are breast carcinoma and SCLC. ANNA-1 and ANNA-2 may be detectable before the associated neoplasm is detectable.
Source: ARUP Laboratories, ANNA
Fully-Specified Name
- Component
- Neuronal nuclear type 1 Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- Hu1 Ab CSF Ql IF
- Display Name
- Neuronal nuclear type 1 Ab IF Ql (CSF)
- Consumer Name Alpha Get Info
- Neuronal nuclear type 1 antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 15707
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG17831-5 | Neuronal nuclear type 1 Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Anticuerpos Antineuronal nuclear tipo 1 Anticuerpos: |
es-MX | Spanish (Mexico) | Ab de tipo 1 nuclear neuronal: |
fr-CA | French (Canada) | Neuronal nucléaire de type 1, Ac: |
fr-FR | French (France) | Hu1 anticorps: |
fr-BE | French (Belgium) | Neuronal nucléaire de type 1 Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Nucleare neuronale tipo 1 Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | neuronaal nucleair type 1 As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Typ 1 neuronalny jądrowy Ab: Synonyms: Przeciwciała do antygenów jądrowych neuronów typu 1 Przeciwciała onkoneuronalne |
pt-BR | Portuguese (Brazil) | Neuronal nuclear tipo 1 Ac: Synonyms: Nuc; |
ru-RU | Russian (Russian Federation) | Нейрональный ядерный тип 1 Ат: Synonyms: Антинейрональный Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Nöronal nükleer tip 1 Ab: Synonyms: Ak Çekirdek İmmünflorerans Mevcut |
zh-CN | Chinese (China) | 神经元细胞核 1 型 抗体: Synonyms: Ⅰ Ab; |
56959-0 Neuronal nuclear type 2 Ab [Presence] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP14164-5 Neuronal nuclear type 2
Type I anti-neuronal nuclear antibody (ANNA-1) is present in patients with paraneoplastic syndromes (paraneoplastic sensory neuropathy or paraneoplastic encephalomyelitis) most commonly associated with small-cell lung carcinoma (SCLC). ANNA-2 is present in patients with midbrain encephalitis, cerebellar ataxia, eye movement disorders (usually opsoclonus), and occasionally myelopathy. Neoplasms most often associated with ANNA-2 are breast carcinoma and SCLC. ANNA-1 and ANNA-2 may be detectable before the associated neoplasm is detectable.
Source: ARUP Laboratories, ANNA
LP39195-0 Neuronal nuclear type 2 Ab
Neuronal nuclear antibody is a neuronal paraneoplastic antibody that has been associated with cerebellar degeneration in breast, small cell lung carcinoma and gynecological cancers.
Source: University of Birmingham, Neuronal antibodies
Fully-Specified Name
- Component
- Neuronal nuclear type 2 Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- Hu2 Ab CSF Ql IF
- Display Name
- Neuronal nuclear type 2 Ab IF Ql (CSF)
- Consumer Name Alpha Get Info
- Neuronal nuclear type 2 antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.29
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 12374
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG5089-0 | Neuronal nuclear type 2 Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Ri/ANNA-2-AK ql IF/L |
es-ES | Spanish (Spain) | Anticuerpos Antineuronal nuclear tipo 2 Anticuerpos: |
es-MX | Spanish (Mexico) | Nuclear neuronal tipo 2 Ab: |
fr-CA | French (Canada) | Neuronal nucléaire de type 2, Ac: |
fr-FR | French (France) | Hu2 anticorps: |
fr-BE | French (Belgium) | Neuronal nucléaire de type 2 Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Nucleare neuronale tipo 2 Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | neuronaal nucleair type 2 As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Typ 2 neuronalny jądrowy Ab: Synonyms: Przeciwciała do antygenów jądrowych komórek nerwowych typu 2 Przeciwciała onkoneuronalne |
pt-BR | Portuguese (Brazil) | Nuclear neuronal tipo 2 Ac: Synonyms: Nuc; |
ru-RU | Russian (Russian Federation) | Нейрональный ядерный тип 2 Ат: Synonyms: Антинейрональный Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Nöronal nükleer tip 2 Ab: Synonyms: Ak Çekirdek İmmünflorerans Mevcut |
zh-CN | Chinese (China) | 神经元细胞核 2 型 抗体: Synonyms: Ⅱ Ab; |
90836-8 Neuronal nuclear type 3 Ab [Presence] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP31707-0 Neuronal nuclear type 3
Neuronal nuclear type 3 Ab (ANNA-3) is one of three neuronal nuclear paraneoplastic antibodies that primarily binds to the nuclei of cerebellar Purkinje neurons and to renal glomerular podocytes. Symptoms of the presence of ANNA-3 include sensory or sensorimotor neuropathies, cerebellar ataxia, myelopathy, brain stem and limbic encephalopathy.It's presence in serum is most commonly indicative of a small-cell malignant tumor, most of which are primary tumors of the lung.Fluorescent staining patterns are used to distinguish ANNA-3 from the other two neuronal nuclear types, ANNA-1 and ANNA-2. ANNA-3 binds the nuclei of Purkinje neurons in the cerebellar cortex more than the molecular neurons, and does not bind granular neurons. ANNA-3 binds only the nuclei of indentate neurons, while ANNA-1 and ANNA-2 bind both the nuclei and cytoplasm of all neurons. ANNA-3 binds the nuclei of glomuerular podocytes in of the renal cortex in 10 of 11 sera. For the same cell type, ANNA-2 binds both the nuclei and cytoplasm in 8 of 32 sera, and ANNA-1 does not bind the podocytes at all. PMID: 11558786
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Neuronal nuclear type 3 Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- Hu3 Ab CSF Ql IF
- Display Name
- Neuronal nuclear type 3 Ab IF Ql (CSF)
- Consumer Name Alpha Get Info
- Neuronal nuclear type 3 antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Example Answer List LL2038-9
Answer | Code | Score | Answer ID |
---|---|---|---|
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Neuronal nuclear tipo 3 Anticuerpos: |
es-MX | Spanish (Mexico) | Tipo nuclear neuronal 3 Ab: |
fr-FR | French (France) | Hu3 anticorps: |
fr-BE | French (Belgium) | Type 3 neuronal nucléaire Ac: Synonyms: Anticorps |
fr-CA | French (Canada) | Neuronal nucléaire de type 3, Ac: |
it-IT | Italian (Italy) | Nucleare neuronale tipo 3 Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | neuronaal nucleair type 3 As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Typ 3 neuronalny jądrowy Ab: Synonyms: Przeciwciała do antygenów jądrowych neuronów typu 3 Przeciwciała onkoneuronalne |
ru-RU | Russian (Russian Federation) | Нейрональный ядерный тип 3 Ат: Synonyms: Антинейрональный Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Nöronal nükleer tip 3 Ab: Synonyms: Ak Çekirdek İmmünflorerans Mevcut |
zh-CN | Chinese (China) | 神经元细胞核 3 型 抗体: Synonyms: Ⅲ Ab; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
90837-6 Neuronal nuclear type 3 Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP31707-0 Neuronal nuclear type 3
Neuronal nuclear type 3 Ab (ANNA-3) is one of three neuronal nuclear paraneoplastic antibodies that primarily binds to the nuclei of cerebellar Purkinje neurons and to renal glomerular podocytes. Symptoms of the presence of ANNA-3 include sensory or sensorimotor neuropathies, cerebellar ataxia, myelopathy, brain stem and limbic encephalopathy.It's presence in serum is most commonly indicative of a small-cell malignant tumor, most of which are primary tumors of the lung.Fluorescent staining patterns are used to distinguish ANNA-3 from the other two neuronal nuclear types, ANNA-1 and ANNA-2. ANNA-3 binds the nuclei of Purkinje neurons in the cerebellar cortex more than the molecular neurons, and does not bind granular neurons. ANNA-3 binds only the nuclei of indentate neurons, while ANNA-1 and ANNA-2 bind both the nuclei and cytoplasm of all neurons. ANNA-3 binds the nuclei of glomuerular podocytes in of the renal cortex in 10 of 11 sera. For the same cell type, ANNA-2 binds both the nuclei and cytoplasm in 8 of 32 sera, and ANNA-1 does not bind the podocytes at all. PMID: 11558786
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Neuronal nuclear type 3 Ab
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- Hu3 Ab Titr CSF IF
- Display Name
- Neuronal nuclear type 3 Ab IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- Neuronal nuclear type 3 antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG50122-7 | Neuronal nuclear type 3 Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Neuronal nuclear tipo 3 Anticuerpos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Tipo nuclear neuronal 3 Ab: |
fr-FR | French (France) | Hu3 anticorps: |
fr-CA | French (Canada) | Neuronal nucléaire de type 3, Ac: |
it-IT | Italian (Italy) | Nucleare neuronale tipo 3 Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | neuronaal nucleair type 3 As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Typ 3 neuronalny jądrowy Ab: Synonyms: Przeciwciała do antygenów jądrowych neuronów typu 3 Przeciwciała onkoneuronalne |
zh-CN | Chinese (China) | 神经元细胞核 3 型 抗体: Synonyms: Ⅲ Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
94356-3 Neuronal nuclear type 1 IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP14163-7 Neuronal nuclear type 1
Type I anti-neuronal nuclear antibody (ANNA-1) is present in patients with paraneoplastic syndromes (paraneoplastic sensory neuropathy or paraneoplastic encephalomyelitis) most commonly associated with small-cell lung carcinoma (SCLC). ANNA-2 is present in patients with midbrain encephalitis, cerebellar ataxia, eye movement disorders (usually opsoclonus), and occasionally myelopathy. Neoplasms most often associated with ANNA-2 are breast carcinoma and SCLC. ANNA-1 and ANNA-2 may be detectable before the associated neoplasm is detectable.
Source: ARUP Laboratories, ANNA
Fully-Specified Name
- Component
- Neuronal nuclear type 1 Ab.IgG
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- Hu1 IgG Titr CSF IF
- Display Name
- Neuronal nuclear type 1 IgG IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- Neuronal nuclear type 1 IgG antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94707-7 | Dementia autoimmune Ab panel - Cerebral spinal fluid |
94708-5 | Encephalopathy autoimmune Ab panel - Cerebral spinal fluid |
94709-3 | Epilepsy autoimmune Ab panel - Cerebral spinal fluid |
94712-7 | Movement disorder autoimmune Ab panel - Cerebral spinal fluid |
94353-0 | Myelopathy autoimmune Ab panel - Cerebral spinal fluid |
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
101416-6 | Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Anticuerpos Antineuronal nuclear tipo 1 IgG: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Tipo 1 nuclear neuronal Ab.IgG: |
fr-CA | French (Canada) | Neuronal nucléaire de type 1, IgG: |
fr-FR | French (France) | Hu1 anticorps IgG: |
it-IT | Italian (Italy) | Nucleare neuronale tipo 1 Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | neuronaal nucleair type 1 As.IgG: Synonyms: antistof; |
pl-PL | Polish (Poland) | Typ 1 neuronalny jądrowy Ab.IgG: Synonyms: IgG Przeciwciała do antygenów jądrowych neuronów typu 1 Przeciwciała IgG do antygenów jądrowych neuronów typu 1 Przeciwciała onkoneuronalne |
zh-CN | Chinese (China) | 神经元细胞核 1 型 抗体.IgG: Synonyms: Ⅰ Ab.IgG; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
94357-1 Neuronal nuclear type 2 IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP14164-5 Neuronal nuclear type 2
Type I anti-neuronal nuclear antibody (ANNA-1) is present in patients with paraneoplastic syndromes (paraneoplastic sensory neuropathy or paraneoplastic encephalomyelitis) most commonly associated with small-cell lung carcinoma (SCLC). ANNA-2 is present in patients with midbrain encephalitis, cerebellar ataxia, eye movement disorders (usually opsoclonus), and occasionally myelopathy. Neoplasms most often associated with ANNA-2 are breast carcinoma and SCLC. ANNA-1 and ANNA-2 may be detectable before the associated neoplasm is detectable.
Source: ARUP Laboratories, ANNA
Fully-Specified Name
- Component
- Neuronal nuclear type 2 Ab.IgG
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- Hu2 IgG Titr CSF IF
- Display Name
- Neuronal nuclear type 2 IgG IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- Neuronal nuclear type 2 IgG antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94707-7 | Dementia autoimmune Ab panel - Cerebral spinal fluid |
94708-5 | Encephalopathy autoimmune Ab panel - Cerebral spinal fluid |
94709-3 | Epilepsy autoimmune Ab panel - Cerebral spinal fluid |
94712-7 | Movement disorder autoimmune Ab panel - Cerebral spinal fluid |
94353-0 | Myelopathy autoimmune Ab panel - Cerebral spinal fluid |
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Anticuerpos Antineuronal nuclear tipo 2 IgG: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Ab.IgG neuronal nuclear tipo 2: |
fr-CA | French (Canada) | Neuronal nucléaire de type 2, IgG: |
fr-FR | French (France) | Hu2 anticorps IgG: |
it-IT | Italian (Italy) | Nucleare neuronale tipo 2 Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | neuronaal nucleair type 2 As.IgG: Synonyms: antistof; |
pl-PL | Polish (Poland) | Typ 2 neuronalny jądrowy Ab.IgG: Synonyms: IgG Przeciwciała do antygenów jądrowych komórek nerwowych typu 2 Przeciwciała jądrowe antyneuronalne typu 2 IgG Przeciwciała onkoneuronalne |
zh-CN | Chinese (China) | 神经元细胞核 2 型 抗体.IgG: Synonyms: Ⅱ Ab.IgG; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
94358-9 Neuronal nuclear type 3 IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP31707-0 Neuronal nuclear type 3
Neuronal nuclear type 3 Ab (ANNA-3) is one of three neuronal nuclear paraneoplastic antibodies that primarily binds to the nuclei of cerebellar Purkinje neurons and to renal glomerular podocytes. Symptoms of the presence of ANNA-3 include sensory or sensorimotor neuropathies, cerebellar ataxia, myelopathy, brain stem and limbic encephalopathy.It's presence in serum is most commonly indicative of a small-cell malignant tumor, most of which are primary tumors of the lung.Fluorescent staining patterns are used to distinguish ANNA-3 from the other two neuronal nuclear types, ANNA-1 and ANNA-2. ANNA-3 binds the nuclei of Purkinje neurons in the cerebellar cortex more than the molecular neurons, and does not bind granular neurons. ANNA-3 binds only the nuclei of indentate neurons, while ANNA-1 and ANNA-2 bind both the nuclei and cytoplasm of all neurons. ANNA-3 binds the nuclei of glomuerular podocytes in of the renal cortex in 10 of 11 sera. For the same cell type, ANNA-2 binds both the nuclei and cytoplasm in 8 of 32 sera, and ANNA-1 does not bind the podocytes at all. PMID: 11558786
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Neuronal nuclear type 3 Ab.IgG
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- Hu3 IgG Titr CSF IF
- Display Name
- Neuronal nuclear type 3 IgG IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- Neuronal nuclear type 3 IgG antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94707-7 | Dementia autoimmune Ab panel - Cerebral spinal fluid |
94708-5 | Encephalopathy autoimmune Ab panel - Cerebral spinal fluid |
94709-3 | Epilepsy autoimmune Ab panel - Cerebral spinal fluid |
94712-7 | Movement disorder autoimmune Ab panel - Cerebral spinal fluid |
94353-0 | Myelopathy autoimmune Ab panel - Cerebral spinal fluid |
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Neuronal nuclear tipo 3 IgG: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Tipo nuclear neuronal 3 Ab.IgG: |
fr-CA | French (Canada) | Neuronal nucléaire de type 3, IgG: |
fr-FR | French (France) | Hu3 anticorps IgG: |
it-IT | Italian (Italy) | Nucleare neuronale tipo 3 Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | neuronaal nucleair type 3 As.IgG: Synonyms: antistof; |
pl-PL | Polish (Poland) | Typ 3 neuronalny jądrowy Ab.IgG: Synonyms: IgG Przeciwciała do antygenów jądrowych neuronów typu 3 Przeciwciała IgG do antygenów jądrowych neuronów typu 3 Przeciwciała onkoneuronalne |
zh-CN | Chinese (China) | 神经元细胞核 3 型 抗体.IgG: Synonyms: Ⅲ Ab.IgG; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
90845-9 PCA-Tr Ab [Presence] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP31709-6 Purkinje cell cytoplasmic type Tr
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264
Source: Regenstrief LOINC
LP39528-2 Purkinje cell cytoplasmic type Tr Ab
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Purkinje cell cytoplasmic type Tr Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- PCA-Tr Ab CSF Ql IF
- Display Name
- PCA-Tr Ab IF Ql (CSF)
- Consumer Name Alpha Get Info
- PCA-Tr antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Example Answer List LL2038-9
Answer | Code | Score | Answer ID |
---|---|---|---|
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG50127-6 | Purkinje cell cytoplasmic type Tr Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Células de Purkinje tipo Tr Anticuerpos: |
es-MX | Spanish (Mexico) | Citoplasma de células de Purkinje tipo Tr Ab: |
fr-FR | French (France) | Tr anticorps: |
fr-BE | French (Belgium) | Cellules de Purkinje type TR Ac: Synonyms: Anticorps |
fr-CA | French (Canada) | Cellules de Purkinje cytoplasmique type Tr, Ac: |
it-IT | Italian (Italy) | Cellule di Purkinje tipo Tr Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | purkinjecellen type Tr As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Cytoplazmatyczne typu Tr komórek Purkinjego Ab: Synonyms: Przeciwciała typu Tr do cytoplazmy komórki Purkinjego |
ru-RU | Russian (Russian Federation) | Пуркинье клетки тип Tr Ат: Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Purkinje hücreleri tip Tr Ab: Synonyms: Ak İmmünflorerans Mevcut |
zh-CN | Chinese (China) | 浦肯雅细胞胞浆 Tr 型 抗体: Synonyms: Ab; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
94362-1 PCA-Tr IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP31709-6 Purkinje cell cytoplasmic type Tr
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Purkinje cell cytoplasmic type Tr Ab.IgG
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- PCA-Tr IgG Titr CSF IF
- Display Name
- PCA-Tr IgG IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- PCA-Tr IgG antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94707-7 | Dementia autoimmune Ab panel - Cerebral spinal fluid |
94708-5 | Encephalopathy autoimmune Ab panel - Cerebral spinal fluid |
94709-3 | Epilepsy autoimmune Ab panel - Cerebral spinal fluid |
94712-7 | Movement disorder autoimmune Ab panel - Cerebral spinal fluid |
94353-0 | Myelopathy autoimmune Ab panel - Cerebral spinal fluid |
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
101416-6 | Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Células de Purkinje tipo Tr IgG: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Citoplasma de células de Purkinje tipo Tr Ab.IgG: |
fr-FR | French (France) | Tr anticorps IgG: |
fr-CA | French (Canada) | Cellules de Purkinje cytoplasmique type Tr, IgG: |
it-IT | Italian (Italy) | Cellule di Purkinje tipo Tr Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | purkinjecellen type Tr As.IgG: Synonyms: antistof; |
pl-PL | Polish (Poland) | Cytoplazmatyczne typu Tr komórek Purkinjego Ab.IgG: Synonyms: IgG Przeciwciała IgG do cytoplazmy komórek Purkinjego typu Tr Przeciwciała typu Tr do cytoplazmy komórki Purkinjego |
zh-CN | Chinese (China) | 浦肯雅细胞胞浆 Tr 型 抗体.IgG: Synonyms: Ab.IgG; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
94363-9 PCA-1 IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP71327-8 Purkinje cell cytoplasmic type 1
Purkinje cell cytoplasmic antibody type 1 (PCA-1) (or anti-Yo) is detected in patients with gynecological or breast adenocarcinoma who present with paraneoplastic cerebellar degeneration. PMID: 1407575 PCA-1 autoimmunity most commonly affects the cerebellum, but the spectrum of neurological symptoms and presentations is broad. Non-cerebellar tissue in the central, peripheral and autonomic nervous systems may also be involved. Neurological outcomes are usually poor, even when cancer remission is achieved. PMID: 21670387
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Purkinje cell cytoplasmic type 1 Ab.IgG
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- PCA-1 IgG Titr CSF IF
- Display Name
- PCA-1 IgG IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- PCA-1 IgG antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94708-5 | Encephalopathy autoimmune Ab panel - Cerebral spinal fluid |
94709-3 | Epilepsy autoimmune Ab panel - Cerebral spinal fluid |
94712-7 | Movement disorder autoimmune Ab panel - Cerebral spinal fluid |
94353-0 | Myelopathy autoimmune Ab panel - Cerebral spinal fluid |
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Células de Purkinje tipo 1 IgG: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Citoplasma de células de Purkinje tipo 1 Ab.IgG: |
fr-FR | French (France) | APCA-1 anticorps IgG: |
fr-CA | French (Canada) | Cellules de Purkinje cytoplasmique type 1, IgG: |
it-IT | Italian (Italy) | Cellule di Purkinje tipo 1 Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | purkinjecellen type 1 As.IgG: Synonyms: antistof; |
pl-PL | Polish (Poland) | Cytoplazmatyczne typu 1 komórek Purkinjego Ab.IgG: Synonyms: IgG PCA-1 Przeciwciała do PCA-1 Przeciwciała IgG do PCA-1 |
zh-CN | Chinese (China) | 浦肯雅细胞胞浆 1 型 抗体.IgG: Synonyms: Ⅰ Ab.IgG; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
94364-7 PCA-2 IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP31708-8 Purkinje cell cytoplasmic type 2
Anti-PCA-2 (purkinje cell cytoplasmic antibody type 2) autoantibodies are important markers of neurological autoimmunity related to cancer. PCA-2 binds to cerebellar Purkinje somata and dendrites, neurons in internal granular layer and dentate nucleus, and neuronal elements in gut and kidney. Patients present with mixed subacute neurological diorders, including brainstem or limbic encephalitis, cerebellar ataxia, Lambert-Eaton myasthenic syndrome, and autonomic and motor neuropathy. Patients with symptoms of such disorders, especially those with known risk factors for cancer, will undergo testing for paraneoplastic antibodies, including PCA-2. Testing is also performed to monitor the immune response of seropositive patients in the course of cancer therapy. PMID: 10716248
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Purkinje cell cytoplasmic type 2 Ab.IgG
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- PCA-2 IgG Titr CSF IF
- Display Name
- PCA-2 IgG IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- PCA-2 IgG antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94707-7 | Dementia autoimmune Ab panel - Cerebral spinal fluid |
94708-5 | Encephalopathy autoimmune Ab panel - Cerebral spinal fluid |
94709-3 | Epilepsy autoimmune Ab panel - Cerebral spinal fluid |
94712-7 | Movement disorder autoimmune Ab panel - Cerebral spinal fluid |
94353-0 | Myelopathy autoimmune Ab panel - Cerebral spinal fluid |
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Células de Purkinje tipo 2 IgG: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Citoplasma de células de Purkinje tipo 2 Ab.IgG: |
fr-FR | French (France) | APCA-2 anticorps IgG: |
fr-CA | French (Canada) | Cellules de Purkinje cytoplasmique type 2, IgG: |
it-IT | Italian (Italy) | Cellule di Purkinje tipo 2 Ab.IgG: Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | purkinjecellen type 2 As.IgG: Synonyms: antistof; |
pl-PL | Polish (Poland) | Cytoplazmatyczne typu 2 komórek Purkinjego Ab.IgG: Synonyms: IgG PCA-2 Przeciwciała IgG do cytoplazmy komórek Purkinjego typu 2 Przeciwciała typu 1 do cytoplazmy komórki Purkinjego |
zh-CN | Chinese (China) | 浦肯雅细胞胞浆 2 型 抗体.IgG: Synonyms: 2 型 Purkinje 细胞 Ab 2 型 Purkinje 细胞抗体 2 型朴金耶细胞 Ab 2 型朴金耶细胞抗体 2 型浦肯雅细胞 Ab 2 型浦肯雅细胞抗体 2 型浦金埃细胞 Ab 2 型浦金埃细胞抗体 Ⅱ Ab.IgG; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
56551-5 PCA-Tr Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP31709-6 Purkinje cell cytoplasmic type Tr
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264
Source: Regenstrief LOINC
LP39528-2 Purkinje cell cytoplasmic type Tr Ab
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Purkinje cell cytoplasmic type Tr Ab
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- PCA-Tr Ab Titr CSF IF
- Display Name
- PCA-Tr Ab IF (CSF) [Titer]
- Consumer Name Alpha Get Info
- PCA-Tr antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.29
- Last Updated
- Version 2.75
- Change Reason
- Changed "Purkinje cells" in Component to the more common name, "Purkinje cell cytoplasmic".
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG20854-2 | Purkinje cell cytoplasmic type Tr Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Células de Purkinje tipo Tr Anticuerpos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Citoplasma de células de Purkinje tipo Tr Ab: |
fr-FR | French (France) | Tr anticorps: |
fr-CA | French (Canada) | Cellules de Purkinje cytoplasmique type Tr, Ac: |
it-IT | Italian (Italy) | Cellule di Purkinje tipo Tr Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
nl-NL | Dutch (Netherlands) | purkinjecellen type Tr As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Cytoplazmatyczne typu Tr komórek Purkinjego Ab: Synonyms: Przeciwciała typu Tr do cytoplazmy komórki Purkinjego |
pt-BR | Portuguese (Brazil) | Células Purkinje tipo Tr Ac: Synonyms: ; |
zh-CN | Chinese (China) | 浦肯雅细胞胞浆 Tr 型 抗体: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
90841-8 PCA-1 Ab [Presence] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP71327-8 Purkinje cell cytoplasmic type 1
Purkinje cell cytoplasmic antibody type 1 (PCA-1) (or anti-Yo) is detected in patients with gynecological or breast adenocarcinoma who present with paraneoplastic cerebellar degeneration. PMID: 1407575 PCA-1 autoimmunity most commonly affects the cerebellum, but the spectrum of neurological symptoms and presentations is broad. Non-cerebellar tissue in the central, peripheral and autonomic nervous systems may also be involved. Neurological outcomes are usually poor, even when cancer remission is achieved. PMID: 21670387
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Purkinje cell cytoplasmic type 1 Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- PCA-1 Ab CSF Ql IF
- Display Name
- PCA-1 Ab IF Ql (CSF)
- Consumer Name Alpha Get Info
- PCA-1 antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Example Answer List LL2038-9
Answer | Code | Score | Answer ID |
---|---|---|---|
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Células de Purkinje tipo 1 Anticuerpos: |
es-MX | Spanish (Mexico) | Ab citoplasmático tipo 1 de células de Purkinje: |
fr-FR | French (France) | APCA-1 anticorps: |
fr-BE | French (Belgium) | Cellules de Purkinje type 1 Ac: Synonyms: Anticorps |
fr-CA | French (Canada) | Cellules de Purkinje cytoplasmique type 1, Ac: |
it-IT | Italian (Italy) | Cellule di Purkinje tipo 1 Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | purkinjecellen type 1 As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Cytoplazmatyczne typu 1 komórek Purkinjego Ab: Synonyms: PCA-1 Przeciwciała do PCA-1 |
ru-RU | Russian (Russian Federation) | Пуркинье клетки тип 1 Ат: Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Purkinje hücreleri tip 1 Ab: Synonyms: Ak İmmünflorerans Mevcut |
zh-CN | Chinese (China) | 浦肯雅细胞胞浆 1 型 抗体: Synonyms: Ⅰ Ab; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
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90843-4 PCA-2 Ab [Presence] in Cerebral spinal fluid by Immunofluorescence
Part Descriptions
LP31708-8 Purkinje cell cytoplasmic type 2
Anti-PCA-2 (purkinje cell cytoplasmic antibody type 2) autoantibodies are important markers of neurological autoimmunity related to cancer. PCA-2 binds to cerebellar Purkinje somata and dendrites, neurons in internal granular layer and dentate nucleus, and neuronal elements in gut and kidney. Patients present with mixed subacute neurological diorders, including brainstem or limbic encephalitis, cerebellar ataxia, Lambert-Eaton myasthenic syndrome, and autonomic and motor neuropathy. Patients with symptoms of such disorders, especially those with known risk factors for cancer, will undergo testing for paraneoplastic antibodies, including PCA-2. Testing is also performed to monitor the immune response of seropositive patients in the course of cancer therapy. PMID: 10716248
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Purkinje cell cytoplasmic type 2 Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- PCA-2 Ab CSF Ql IF
- Display Name
- PCA-2 Ab IF Ql (CSF)
- Consumer Name Alpha Get Info
- PCA-2 antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Example Answer List LL2038-9
Answer | Code | Score | Answer ID |
---|---|---|---|
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
Indeterminate Copyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Member of these Panels
LOINC | Long Common Name |
---|---|
94818-2 | Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG51341-2 | Purkinje cell cytoplasmic type 2 Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Células de Purkinje tipo 2 Anticuerpos: |
es-MX | Spanish (Mexico) | Ab citoplasmático tipo 2 de células de Purkinje: |
fr-FR | French (France) | APCA-2 anticorps: |
fr-BE | French (Belgium) | Cellules de Purkinje type 2 Ac: Synonyms: Anticorps |
fr-CA | French (Canada) | Cellules de Purkinje cytoplasmique type 2, Ac: |
it-IT | Italian (Italy) | Cellule di Purkinje tipo 2 Ab: Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | purkinjecellen type 2 As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Cytoplazmatyczne typu 2 komórek Purkinjego Ab: Synonyms: PCA-2 Przeciwciała typu 1 do cytoplazmy komórki Purkinjego |
ru-RU | Russian (Russian Federation) | Пуркинье клетки тип 2 Ат: Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Purkinje hücreleri tip 2 Ab: Synonyms: Ak İmmünflorerans Mevcut |
zh-CN | Chinese (China) | 浦肯雅细胞胞浆 2 型 抗体: Synonyms: 2 型 Purkinje 细胞 Ab 2 型 Purkinje 细胞抗体 2 型朴金耶细胞 Ab 2 型朴金耶细胞抗体 2 型浦肯雅细胞 Ab 2 型浦肯雅细胞抗体 2 型浦金埃细胞 Ab 2 型浦金埃细胞抗体 Ⅱ Ab; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.