LOINC
Version 2.68

95411-5SARS-CoV-2 (COVID-19) neutralizing antibody [Presence] in Serum by pVNTActive

Term Description

Qualitative results for SARS Coronavirus 2 (SARS-CoV-2) virus neutralizing antibodies in serum by pVNT (pseudovirus neutralization test). Neutralizing antibody testing is performed to determine whether the antibodies produced after SARS-CoV-2 infection or in response to a vaccination are able to neutralize the virus and prevent infection or re-infection. Different methods can be used to determine the presence of neutralizing antibodies, including VNT (virus neutralization test) and pVNT, which are represented in LOINC as the Method "Neutralization" and "pVNT", respectively. The pVNT method for SARS-CoV-2 neutralizing antibody testing uses recombinant pseudoviruses that incorporate the S protein from SARS-CoV-2, whereas VNT uses SARS-CoV-2 virus from a clinical isolate or recombinant SARS-CoV-2 expressing reporter proteins.
Source: Regenstrief LOINC

Fully-Specified Name

Component
SARS coronavirus 2 Ab.neut
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
pVNT

Additional Names

Short Name
SARS-CoV-2 NAb Ser Ql pVNT
Display Name
SARS-CoV-2 (COVID-19) neut ab pVNT Ql (S)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Both

Example Answer List LL2009-0

Source: ARUP Laboratories

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Equivocal Copyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value) LA11885-3

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2001-2019 American Association for Clinical Chemistry Coronavirus (COVID-19) Testing

Member of these Groups

LG51018-6 SARSCoV2 antibody detection

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95411-5