Version 2.80

Term Description

The detection of rearrangements involving the TFEB gene by FISH. A positive result suggests a rearrangement of the TFEB gene region at 6p21.1 and supports the diagnosis of renal cell carcinoma (RCC).

Part Descriptions

LP420083-0   TFEB gene rearrangements
The TFEB (transcription factor EB) gene [HGNC Gene ID: 11753] is located on chromosome 6 at position p21.1. Rearrangements involving the TFEB gene has been observed in a subset of renal cell carcinoma. PMID: 24618616 PMID: 27565001 Source: Regenstrief LOINC

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , FISH

Fully-Specified Name

Component
TFEB gene rearrangements
Property
Find
Time
Pt
System
Tiss
Scale
Doc
Method
FISH

Additional Names

Long Common Name
TFEB gene rearrangements in Tissue by FISH
Short Name
TFEB rearrange Tiss FISH
Display Name
TFEB gene rearrangements FISH Doc (Tiss)
Consumer Name Alpha Get Info
TFEB gene rearrangements, Tissue

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69 (ADD)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Γονιδιακές αναδιατάξεις TFEB:Εύρεση:Pt:Ιστός:Doc:Φθορίζουσα υβριδοποίηση in situ
Synonyms: Γονιδιακές αναδιατάξεις TFEB Γονίδιο Εύρεση
es-ES Spanish (Spain) Reordenamientos del gen TFEB:Hallazgo:Punto temporal:Tejido:Doc:Hibridación in situ fluoresente (FISH)
es-MX Spanish (Mexico) Reordenamientos del gen TFEB:Hallazgo:Punto temporal:Tejido y frotis:Documento:Hibridación fluorescente in situ (FISH)
fr-FR French (France) TFEB gène réarrangements:Recherche:Ponctuel:Tissu:Document:FISH
it-IT Italian (Italy) TFEB, gene riarrangiamenti:Osservazione:Pt:Tessuto:Doc:FISH
Synonyms: Ibridazione in situ fluorescente (FISH) Osservazione Patologia molecolare Punto nel tempo (episodio) Tessuto & Strisci
nl-NL Dutch (Netherlands) TFEB-genherschikking:bevinding:moment:weefsel en uitstrijkjes:document:FISH
Synonyms: TFEB-gentranslocaties
zh-CN Chinese (China) TFEB 基因重排:发现:时间点:组织与涂片:文档型:FISH
Synonyms: Fluorescent in situ hybridization;荧光原位杂交 TFEB 基因重排（重组） 临床文档型;临床文档;文档;文书;医疗文书;临床医疗文书 分子病理学;分子病理学试验 发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95780-3