95834-8
Mononuclear cells [#] in Blood product unit
Active
Part Description
LP17839-9 Mononuclear cells
A Peripheral Blood Mononuclear Cell (PBMC) is a blood cell having a round nucleus, such as a lymphocyte or a monocyte. These blood cells are a critical component in the immune system to fight infection and adapt to intruders. The lymphocyte population consists of T cells (CD4 and CD8 positive ~75%), B cells and NK cells (~25% combined).
These cells are often extracted from whole blood using ficoll, a hydrophilic polysaccharide that separates layers of blood, with monocytes and lymphocytes forming a buffy coat under a layer of plasma. This buffy coat contains the PBMCs. Additionally, PBMC can be extracted from whole blood using a hypotonic lysis which will preferentially lyse red blood cells. This method results in neutrophils and other polymorphonuclear (PMN) cells which are important in innate immune defense to be obtained.
PBMCs are widely used in research and clinical uses every day. HIV research uses them because PBMCs include CD4+ cells, the cells HIV infects.
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Source: Wikipedia, Mononuclear cell
Fully-Specified Name
- Component
- Mononuclear cells
- Property
- Num
- Time
- Pt
- System
- ^BPU
- Scale
- Qn
- Method
Additional Names
- Short Name
- Mononuc Cells BPU
- Display Name
- Mononuclear cells (BPU) [#]
- Consumer Name Alpha Get Info
- Mononuclear cells, Blood Product Unit
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 2.69
- Last Updated
- Version 2.69
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
95830-6 | Hematopoietic progenitor cell product characterization panel - Blood product unit by Flow cytometry (FC) |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Mononucleares: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Células mononucleares: |
fr-BE | French (Belgium) | Cellules mononucléaires: Synonyms: Cellules mononucléées |
fr-FR | French (France) | Cellules mononucléées: |
fr-CA | French (Canada) | Cellules mononucléaires: |
it-IT | Italian (Italy) | Cellule mononucleari: Synonyms: Banca del sangue Numero (conta) Punto nel tempo (episodio) Unità di prodotto sangue |
nl-NL | Dutch (Netherlands) | mononucleaire cellen: |
pl-PL | Polish (Poland) | Mononuklearne komórki: Synonyms: Mononuklearne komórki |
ru-RU | Russian (Russian Federation) | Мононуклеарные клетки: Synonyms: Количественный Количество Кровь препарат единица; |
tr-TR | Turkish (Turkey) | Mononükleer hücreler: |
zh-CN | Chinese (China) | 单个核细胞: Synonyms: BPU; |
Example Units
Unit | Source |
---|---|
10*8 | Example UCUM Units |
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