95970-0

SARS-CoV-2 (COVID-19) specific TCRB gene rearrangements [Presence] in Blood by Sequencing

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Term Description

This term is intended to report assays that apply disease-specific algorithms to the sequence information from rearranged T-cell receptor beta (TCRB) gene (i.e., the T-cell receptor repertoire) to assign a qualitative result that determines recent or prior infection by SARS-CoV-2.
Source: Regenstrief LOINC

Part Description

LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing

Fully-Specified Name

Component: SARS coronavirus 2 specific TCRB gene rearrangements
Property: PrThr
Time: Pt
System: Bld
Scale: Ord
Method: Sequencing

Additional Names

Short Name: SARS-CoV-2 TCRB Bld Ql Seq
Display Name: SARS-CoV-2 (COVID-19) specific TCRB gene rearrangements Sequencing Ql (Bld)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) specific TCRB gene rearrangements, Blood

Example Answer List: LL2021-5

Source: Gen-Probe

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value)			LA15841-2

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.69
Last Updated: Version 2.69
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2-spezifische TCRB Gen-Rearrangements:Nachweis oder Schwellenwert:Zeitpunkt:Blut:Ordinal:Sequenzierung
es-ES	Spanish (Spain)	Reordenamientos genéticos específicos de TCRB del SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Sangre:Ord:Secuenciación
es-MX	Spanish (Mexico)	Reordenamientos del gen TCRB específicos del coronavirus 2 del SARS:Presencia o umbral:Punto temporal:Sangre:Ordinal:Secuenciación
fr-FR	French (France)	Coronavirus SARS-CoV-2 réarrangements gène TCRB:Présence/Seuil:Ponctuel:Sang:Qualitatif:Séquençage
it-IT	Italian (Italy)	SARS coronavirus 2, specifici riarrangiamenti del gene TCRB:PrThr:Pt:Sangue:Ord:Sequenziamento Synonyms: Coronavirus della SARS Microbiologia Presenza o Soglia Punto nel tempo (episodio) Riarrangiamenti di gene del TCRB Sangue SARS CoV-2 (COVID-19), specifici riarrangiamenti del gene TCRB SARS-CoV-2 (COVID-19)
nl-NL	Dutch (Netherlands)	SARS-CoV-2-specifieke TCRB-genherschikking:aanwezigheid:moment:bloed:ordinaal:sequencing Synonyms: SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19; gentranslocatie TCRB-gentranslocaties
pl-PL	Polish (Poland)	Rearanżacja specyficznego genu TCRB SARS-CoV-2:granica wykrywalności:punkt w czasie:krew:półilościowy:sekwencjonowanie Synonyms: Koronawirus
zh-CN	Chinese (China)	SARS 冠状病毒 2 特异性 TCRB 基因重排:存在情况或阈值:时间点:全血:序数型:序列测定 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II SARS 冠状病毒 2 特异性 TCRB 基因重排（重组）;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒 TCRB 基因重排（重组）;T 细胞受体 Beta 链;T 细胞受体β链;TCR β链;克隆性;淋巴瘤;白血病;集落性依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）序列分析;测序微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间特异特异性的特异的血;血液遗传基因;遗传因子;吉恩;生物基因

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.