Version 2.72

95970-0SARS-CoV-2 (COVID-19) specific TCRB gene rearrangements [Presence] in Blood by SequencingActive

Term Description

This term is intended to report assays that apply disease-specific algorithms to the sequence information from rearranged T-cell receptor beta (TCRB) gene (i.e., the T-cell receptor repertoire) to assign a qualitative result that determines recent or prior infection by SARS-CoV-2.
Source: Regenstrief LOINC

Part Description

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977.[PMID:271968] Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost.[PMID:18576944] Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template.[PMID:20858600] Source: Regenstrief LOINC

Fully-Specified Name

SARS coronavirus 2 specific TCRB gene rearrangements

Additional Names

Short Name
SARS-CoV-2 TCRB Bld Ql Seq
Display Name
SARS-CoV-2 (COVID-19) specific TCRB gene rearrangements Sequencing Ql (Bld)
Consumer Name Alpha
SARS-CoV-2 (COVID-19) specific TCRB gene rearrangements, Blood

Example Answer List LL2021-5

Source: Gen-Probe

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Invalid Copyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) LA15841-2

Basic Attributes

First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Coronavirus (COVID-19) Testing

Member of these Groups

LG51017-8 SARSCoV2 detection
LG51019-4 SARSCoV2 molecular detection

Language Variants Get Info

zh-CNChinese (China)
SARS 冠状病毒 2 特异性 TCRB 基因重排:存在情况或阈值:时间点:全血:序数型:序列测定
nl-NLDutch (Netherlands)
SARS-CoV-2-specifieke TCRB-gentranslocaties:aanwezigheid:moment:bloed:ordinaal:sequencing
fr-FRFrench (France)
Coronavirus SARS-CoV-2 réarrangements gène TCRB:Présence/Seuil:Ponctuel:Sang:Qualitatif:Séquençage
de-DEGerman (Germany)
SARS-Coronavirus 2-spezifische TCRB Gen-Rearrangements:Nachweis oder Schwellenwert:Zeitpunkt:Blut:Ordinal:Sequenzierung
it-ITItalian (Italy)
SARS coronavirus 2, specifici riarrangiamenti del gene TCRB:PrThr:Pt:Sangue:Ord:Sequenziamento
pl-PLPolish (Poland)
rearanżacja specyficznego genu TCRB SARS-CoV-2:obecność lub wartość progowa:Punkt w czasie:Krew:Porządkowy:Sekwencjonowanie
es-MXSpanish (Mexico)
Reordenamientos del gen TCRB específicos del coronavirus 2 del SARS:Presencia o umbral:Punto temporal:Sangre:Ordinal:Secuenciación
es-ESSpanish (Spain)
Reordenamientos genéticos específicos de TCRB del SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Sangre:Ord:Secuenciación

LOINC FHIR® API Example - CodeSystem Request Get Info