Version 2.77

Term Description

The GALAD score provides the probability of a patient having hepatocellular carcinoma (HCC). It is calculated based on gender, age, alpha-fetoprotein (AFP)-L3, AFP, and des-gamma-carboxy prothrombin [DCP], and higher GALAD model scores correlate with increased risk of HCC. The GALAD model is reported to be more accurate in diagnosing HCC compared to the use of the individual markers.
Source: Regenstrief LOINC

Part Description

LP421438-5   GALAD
The GALAD model is a statistical model for estimating the likelihood of hepatocellular carcinoma (HCC) in patients with chronic liver disease. The GALAD score is calculated based on gender, age, and concentrations of AFL-L3, AFP, and des-gamma-carboxy prothrombin (DCP). The GALAD model has been demonstrated to have higher diagnostic accuracy for the detection of HCC compared to these individual markers alone or in combination, as well as reported to be superior to ultrasound for HCC detection PMID: 30464023. Source: Regenstrief LOINC

Fully-Specified Name

Component
Hepatocellular carcinoma risk
Property
Score
Time
Pt
System
^Patient
Scale
Qn
Method
GALAD

Additional Names

Short Name
GALAD Score
Display Name
Hepatotocellular carcinoma risk [Score] GALAD
Consumer Name Alpha Get Info
Hepatocellular carcinoma risk

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.70
Change Reason
Release 2.70: COMPONENT: Corrected typo Hepatotocellular to Hepatocellular.;
Order vs. Observation
Observation

Formula (Readable)

Z = -10.08 + 0.09 x age + 1.67 x sex + 2.34 log(10) (AFP) + 0.04 x AFP - L3 + 1.33 x log(10) (DCP), where sex = 1 for males, 0 for females.

Member of these Panels

LOINC Long Common Name
96452-8 Hepatocellular carcinoma risk panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG51398-2 Hepatocellular carcinoma risk|Score|Pt|^Patient

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Riesgo de carcinoma hepatocelular:Puntuación:Punto temporal:^paciente:Qn:GALAD
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Riesgo de carcinoma hepatotocelular:Puntaje:Punto temporal:^ Paciente:Cuantitativo:GALAD
fr-FR French (France) Risque de cancer hépatocellulaire:Score:Ponctuel:Patient:Numérique:GALAD
it-IT Italian (Italy) Carcinoma epatocellulare, rischio:Punteggio:Pt:^Paziente:Qn:GALAD
Synonyms: Chimica paziente Punto nel tempo (episodio)
zh-CN Chinese (China) 肝细胞癌:评分:时间点:^患者:定量型:GALAD
Synonyms: 分值;得分;分数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 医疗服务对象;客户;病人;病患;病号;超系统 - 病人 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 性别、年龄、甲胎蛋白（AFP、alpha-fetoprotein、α-胎儿球蛋白）-L3、甲胎蛋白（AFP、alpha-fetoprotein、α-胎儿球蛋白）和脱-γ-羧基凝血酶原（DCP、异常凝血酶原、PIVKA-II、维生素K缺乏或拮抗剂-II诱导的蛋白、Protein Induced by Vitamin K Absence or Antagonist-II）;GALAD 法;Gender, Age, Alpha-fetoprotein (AFP)-L3, AFP, and Des-gamma-c 时刻;随机;随意;瞬间 肝癌;HCC

Example Units

Unit Source
{score} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96450-2