Version 2.78

Term Description

The detection and differentiation of HIV 1 & 2 in serum or plasma specimens by nucleic acid amplification (NAA) with probe-based detection methods.
Source: Regenstrief LOINC

Part Description

LP36650-7   HIV 1 & 2
Human immunodeficiency virus (HIV) is categorized into two types, HIV-1 and HIV-2. Worldwide, most HIV infections are HIV-1, whereas HIV-2 largely has been confined to persons in or from West Africa (1,2). HIV-1 and HIV-2 have the same routes of transmission, and both can cause acquired immunodeficiency syndrome (AIDS) (3); however, HIV-2 infections should be differentiated from HIV-1 infections because they are less likely to cause AIDS and their clinical management differs (4,5). CDC's current surveillance case definition for HIV infection applies to both variants of HIV (6) but lacks criteria for differentiating between HIV-1 and HIV-2.

To enumerate and describe HIV-2 cases reported in the United States, a working case definition was developed. During 1988 through June 2010, a total of 242 HIV-2 cases were reported to CDC. Of these, 166 met the working definition. These HIV-2 cases were concentrated in the Northeast (66%, including 46% in New York City) and occurred primarily among persons born in West Africa (81%). Ninety-seven of the HIV-2 cases also had a positive HIV-1 immunoblot antibody test result (e.g., Western blot). Immunoblot antibody tests currently used to confirm HIV reactive screening tests do not contain reagents specific to HIV-2 and thus are not reliable for identification of HIV-2 infections (7). Additional testing specific to HIV-2 should be considered if HIV-1 test results are atypical or inconsistent with clinical findings, especially for persons from West Africa. If an HIV case is reported to the health department but subsequently identified as HIV-2, health-care providers should update the case report to reflect the correct type. As of June 2012, the Bio-Rad Multispot HIV-1/HIV-2 Rapid Test is FDA approved for distinguishing HIV1 from HIV2. Source: Centers for Disease Control and Prevention, LV Torian, et al. HIV-2 Infection Surveillance -- United States, 1987-2009. Morbidity and Mortality Weekly Report 60(29);985-988. July 29, 2011.

Fully-Specified Name

Component
HIV 1 & 2 RNA
Property
Prid
Time
Pt
System
Ser/Plas
Scale
Nom
Method
Probe.amp.tar

Additional Names

Short Name
HIV 1 & 2 RNA SerPl NAA+probe
Display Name
HIV 1 and 2 RNA NAA+probe Nom
Consumer Name Alpha Get Info
HIV 1 and 2, Blood

Example Answer List: LL5696-1

Source: Roche Diagnostics International
Answer Code Score Answer ID
Positive for HIV 1 LA20963-7
Positive for HIV 2 LA20964-5
NonreactiveCopyright http://snomed.info/sct ID:131194007 Non-reactive (qualifier value) LA15256-3
InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) LA15841-2

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
96557-4 HIV 1 and 2 RNA panel - Serum or Plasma by NAA with probe detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) HIV-1 & 2 RNA:Nachweis oder Identität:Zeitpunkt:Serum oder Plasma:Nominal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) HIV 1 y 2 RNA:Presencia o identidad:Punto temporal:Suero o Plasma:Nom:Sonda con amplificación dirigida
es-MX Spanish (Mexico) ARN del VIH 1 y 2:Presencia o identidad:Punto temporal:Suero o Plasma:Nominal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) VIH-1 et VIH-2 ARN:Identification:Ponctuel:Sérum/Plasma:Résultat nominal:PCR amplification de cible
fr-BE French (Belgium) VIH 1 & 2 ARN:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Sonde avec amplification de la cible
Synonyms: HIV HIV 1 HIV 1&2 HIV 1+2
fr-CA French (Canada) VIH 1 & 2 ARN:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Sonde avec amplification de la cible
it-IT Italian (Italy) HIV 1 & 2 RNA:Prid:Pt:Siero/Plasma:Nom:Sonda.amp.tar
Synonyms: Microbiologia Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) HIV 1 & 2 RNA:identificator:moment:serum of plasma:nominaal:probe-detectie
Synonyms: probe.amp.tar
ru-RU Russian (Russian Federation) HIV 1 & 2 РНК:ПрИд:ТчкВрм:Сыв/Плаз:Ном:Проба.усил.миш
Synonyms: ВИЧ ВИЧ 1 ВИЧ 1 и 2 ВИЧ 1+2 ДНК проба;ДНК зонд Номинальный;Именной Плазма Присутствие или Идентификация Проба с мишени усилением Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) HIV 1 ve 2 RNA:MevcKimlik:Zmlı:Ser/Plaz:Snf:Prob.amf.hdf
zh-CN Chinese (China) HIV 1 型 与 2 型 RNA:存在与否或特征标识:时间点:血清/血浆:名义型:探针法.基因扩增.靶向
Synonyms: Ⅰ Ⅱ AIDS;AIDS 病毒;人类免疫缺陷病毒;人类免疫缺陷病毒（Human immunodeficiency virus，HIV）;爱滋病;艾滋病;艾滋病病毒;获得性免疫缺陷综合征;获得性免疫缺陷综合征（Acquired Immure Deficiency Syndrome，AIDS，艾滋病） HIV1;HTLV 3;HTLV III;人类免疫缺陷病毒 1 型;人类免疫缺陷病毒 I 型;HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） I II 人类免疫缺陷病毒 1 与 2 型;HIV（人类免疫缺陷病毒、人免疫缺陷病毒、艾滋病病毒） 1 型（I 型） 与 2 型（II 型） 人类免疫缺陷病毒 1+2 型;HIV 1+2 型（人类免疫缺陷病毒 1+2 型、人类免疫缺陷病毒 I+II 型、人免疫缺陷病毒 1+2 型、人免疫缺陷病毒 I+II 型、HIV I+II、HIV I+II 型、艾滋病病毒 I+II 型） 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 经过扩增的 脱氧核糖核酸探针 血清或血浆

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