96556-6

HIV 1 and 2 RNA [Identifier] in Serum or Plasma by NAA with probe detection

Active

Term Description

The detection and differentiation of HIV 1 & 2 in serum or plasma specimens by nucleic acid amplification (NAA) with probe-based detection methods.

Part Description

LP36650-7 HIV 1 & 2
Human immunodeficiency virus (HIV) is categorized into two types, HIV-1 and HIV-2. Worldwide, most HIV infections are HIV-1, whereas HIV-2 largely has been confined to persons in or from West Africa (1,2). HIV-1 and HIV-2 have the same routes of transmission, and both can cause acquired immunodeficiency syndrome (AIDS) (3); however, HIV-2 infections should be differentiated from HIV-1 infections because they are less likely to cause AIDS and their clinical management differs (4,5). CDC's current surveillance case definition for HIV infection applies to both variants of HIV (6) but lacks criteria for differentiating between HIV-1 and HIV-2.

To enumerate and describe HIV-2 cases reported in the United States, a working case definition was developed. During 1988 through June 2010, a total of 242 HIV-2 cases were reported to CDC. Of these, 166 met the working definition. These HIV-2 cases were concentrated in the Northeast (66%, including 46% in New York City) and occurred primarily among persons born in West Africa (81%). Ninety-seven of the HIV-2 cases also had a positive HIV-1 immunoblot antibody test result (e.g., Western blot). Immunoblot antibody tests currently used to confirm HIV reactive screening tests do not contain reagents specific to HIV-2 and thus are not reliable for identification of HIV-2 infections (7). Additional testing specific to HIV-2 should be considered if HIV-1 test results are atypical or inconsistent with clinical findings, especially for persons from West Africa. If an HIV case is reported to the health department but subsequently identified as HIV-2, health-care providers should update the case report to reflect the correct type. As of June 2012, the Bio-Rad Multispot HIV-1/HIV-2 Rapid Test is FDA approved for distinguishing HIV1 from HIV2. Source: Centers for Disease Control and Prevention, LV Torian, et al. HIV-2 Infection Surveillance -- United States, 1987-2009. Morbidity and Mortality Weekly Report 60(29);985-988. July 29, 2011.

LOINC Names Get Info

Fully-Specified Name: HIV 1 & 2 RNA:Prid:Pt:Ser/Plas:Nom:Probe.amp.tar
Long Common Name: HIV 1 and 2 RNA [Identifier] in Serum or Plasma by NAA with probe detection
Short Name: HIV 1 & 2 RNA SerPl NAA+probe
Display Name: HIV 1 and 2 RNA NAA+probe Nom
Consumer Name Alpha Get Info: HIV 1 and 2, Blood

Part Model Get Info

Component
HIV 1 & 2 RNA
LP420675-3
- Analyte
  HIV 1 & 2 RNA
  LP420675-3
  - Component Numerator
    HIV 1 & 2 RNA
    LP420675-3
    - Component Numerator Core
      HIV 1 & 2
      LP36650-7
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Prid
LP6850-4
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Nom
LP7750-5
Method
Probe.amp.tar
LP6464-4

Example Answer List: LL5696-1

Source: Roche Diagnostics International

Answer	Code	Score	Answer ID
Positive for HIV 1			LA20963-7
Positive for HIV 2			LA20964-5
NonreactiveCopyright http://snomed.info/sct ID:131194007 Non-reactive (qualifier value)			LA15256-3
InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value)			LA15841-2

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.69
Last Updated: Version 2.69 (ADD)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
96557-4	HIV 1 and 2 RNA panel - Serum or Plasma by NAA with probe detection

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	HIV 1 a 2 RNA:Přítomnost nebo identita:Časový bod:Sérum/plazma:Nominální:Amplifikace nukleových kyselin s detekcí sondou
de-DE	German (Germany)	HIV-1 & 2 RNA:Nachweis oder Identität:Zeitpunkt:Serum oder Plasma:Nominal:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Ιός ανθρώπινης ανοσοανεπάρκειας 1 & 2 RNA:Prid:Pt:Ορός/Πλάσμα:Nom:Ανιχνευτής.ενίσχυση.στόχου Synonyms: HIV 1 MICRO Nom Prid Pt RNA Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ιός ανθρώπινης ανοσοανεπάρκειας Ιός ανθρώπινης ανοσοανεπάρκειας 1 & 2 Ιός ανθρώπινης ανοσοανεπάρκειας 1+2 Ορός Ορός/Πλάσμα Πλάσμα
es-ES	Spanish (Spain)	HIV 1 y 2 RNA:Presencia o identidad:Punto temporal:Suero o Plasma:Nom:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	ARN del VIH 1 y 2:Presencia o identidad:Punto temporal:Suero o Plasma:Nominal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	VIH 1 et 2 ARN:Identification:Ponctuel:Sérum/Plasma:Résultat nominal:PCR amplification de cible
fr-BE	French (Belgium)	VIH 1 & 2 ARN:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Sonde avec amplification de la cible Synonyms: HIV HIV 1 HIV 1&2 HIV 1+2
fr-CA	French (Canada)	VIH 1 & 2 ARN:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Sonde avec amplification de la cible
it-IT	Italian (Italy)	HIV 1 & 2 RNA:Prid:Pt:Siero/Plasma:Nom:Sonda.amp.tar Synonyms: Microbiologia Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	HIV 1 & 2 RNA:identificator:moment:serum of plasma:nominaal:probe-detectie Synonyms: probe.amp.tar
pl-PL	Polish (Poland)	HIV 1 i 2 RNA:obecność lub identyfikacja:punkt w czasie:surowica lub osocze:skala nominalna:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Ludzki wirus niedoboru odporności Ludzki wirus niedoboru odporności typu 1 Ludzki wirus niedoboru odporności typu 1 i 2 Ludzki wirus niedoboru odporności typu 1+2 wynik kategorialny
ru-RU	Russian (Russian Federation)	HIV 1 & 2 РНК:ПрИд:ТчкВрм:Сыв/Плаз:Ном:Проба.усил.миш Synonyms: ВИЧ ВИЧ 1 ВИЧ 1 и 2 ВИЧ 1+2 ДНК проба;ДНК зонд Номинальный;Именной Плазма Присутствие или Идентификация Проба с мишени усилением Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	HIV 1 ve 2 RNA:MevcKimlik:Zmlı:Ser/Plaz:Snf:Prob.amf.hdf
zh-CN	Chinese (China)	HIV 1 型与 2 型 RNA:存在与否或特征标识:时间点:血清/血浆:名义型:探针法.基因扩增.靶向 Synonyms: Ⅰ Ⅱ AIDS;AIDS 病毒;人类免疫缺陷病毒;人类免疫缺陷病毒（Human immunodeficiency virus，HIV）;爱滋病;艾滋病;艾滋病病毒;获得性免疫缺陷综合征;获得性免疫缺陷综合征（Acquired Immure Deficiency Syndrome，AIDS，艾滋病） HIV1;HTLV 3;HTLV III;人类免疫缺陷病毒 1 型;人类免疫缺陷病毒 I 型;HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） I II 人类免疫缺陷病毒 1 与 2 型;HIV（人类免疫缺陷病毒、人免疫缺陷病毒、艾滋病病毒） 1 型（I 型）与 2 型（II 型）人类免疫缺陷病毒 1+2 型;HIV 1+2 型（人类免疫缺陷病毒 1+2 型、人类免疫缺陷病毒 I+II 型、人免疫缺陷病毒 1+2 型、人免疫缺陷病毒 I+II 型、HIV I+II、HIV I+II 型、艾滋病病毒 I+II 型）借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答存在;存在与否;特征标识;身份;身份标识微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 经过扩增的脱氧核糖核酸探针血清或血浆

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