Version 2.77

Term Description

Qualitative detection of nucleic acids within the membrane (M) gene of SARS coronavirus 2 (SARS-CoV-2) in upper respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Part Description

LP422882-3   SARS coronavirus 2 M gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Coronavirus (COVID-19) Testing

Fully-Specified Name

Component
SARS coronavirus 2 M gene
Property
PrThr
Time
Pt
System
Respiratory system specimen.upper
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
SARS-CoV-2 M gene Upper resp Ql NAA+prb
Display Name
SARS-CoV-2 (COVID-19) M gene NAA+probe Ql (Upper resp)
Consumer Name Alpha Get Info
SARS-CoV-2 (COVID-19) M gene, Upper respiratory

Example Answer List: LL2021-5

Source: Gen-Probe
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) LA15841-2

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.77
Change Reason
Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG51017-8 SARSCoV2 detection
LG51019-4 SARSCoV2 molecular detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) SARS-Coronavirus 2 M-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom oberen Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-MX Spanish (Mexico) Gen del coronavirus 2 M del SARS:PrThr:Punto temporal:Respiratorio superior:Ordinal:Probe.amp.tar
fr-FR French (France) Coronavirus SARS-CoV-2 gène M:Présence/Seuil:Ponctuel:Voies respiratoires supérieures:Qualitatif:PCR amplification de cible
nl-NL Dutch (Netherlands) SARS-CoV-2 M-gen:aanwezigheid:moment:bovenste luchtwegen:ordinaal:probe-detectie
Synonyms: bovenste ademhalingsstelsel; systema respiratorium superior probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96957-6