Version 2.78

Part Description

LP422368-3   Comment on overall fetal aneuploidy risk
Noninvasive prenatal screening is used to assess fetal risk for various genetic conditions without requiring invasive maternal procedures such as amniocentesis or chorionic villus sampling. Cell-free DNA (cfDNA) in maternal plasma comes from both fetal and maternal sources, and various platforms have been developed using cfDNA to determine fetal risk. Natera's Panorama prenatal screening test uses a single blood sample from a pregnant woman, and using their proprietary informatics analysis method (NATUS), effectively subtracts the maternal genotype (from WBC DNA) from the cfDNA genotype and analyzes the remaining fetal cfDNA genotype for a variety of conditions including aneuploidy (e.g., Trisomy 21, Monosomy X) and microdeletions (e.g., 22q11.2 deletion). Specific results are typically reported for each individual condition and summarized for the report as a whole -- if the risk of any individual condition is high, the overall interpretation is "high risk," and if all the individual risks are low, the overall interpretation is "low risk." In addition, the genetic counselor who reviews the results may add specific interpretation details or follow-up recommendations to the report. Source: Regenstrief LOINC

Fully-Specified Name

Component
Comment on overall fetal aneuploidy risk
Property
Txt
Time
Pt
System
WBC.DNA+Plas.cfDNA
Scale
Nar
Method
Dosage of chromosome specific cf DNA

Additional Names

Short Name
Comment aneu risk WBC.DNA+cfDNA
Display Name
Comment on overall fetal aneuploidy risk Dosage of chromosome-specific cfDNA Nar (Plasma cell-free+WBC DNA)
Consumer Name Alpha Get Info
Comment on overall fetal aneuploidy risk

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
96977-4 Noninvasive prenatal fetal aneuploidy panel - Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Comentario sobre el riesgo general de aneuploidía fetal:Texto:Punto temporal:ADN en plasma libre de células y leucocitos:Narrativo:Dosificación de ADN ccf de cromosoma específico
es-MX Spanish (Mexico) Comente sobre el riesgo general de aneuploidía fetal:TXT:Punto temporal:WBC.DNA + Plas.cfDNA:Narrativo:Dosificación de ADN cf cromosómico específico
fr-FR French (France) Risque global d'aneuploïdie foetale (Commentaire):Texte:Ponctuel:Leucocytes ADN+Plasma avec ADN libre circulant:Résultat textuel:Dosage d'ADN libre circulant spécifiques aux chromosomes
it-IT Italian (Italy) Commento su rischio generale aneuploidaia fetale:Txt:Pt:WBC.DNA+Plas.cfDNA:Nar:Dosaggio di DNA libero fetale circolante cromosoma specifico
Synonyms: DNA libero circolante nel plasma Dosaggio di DNA libero fetale circolante cromosoma Globuli bianchi Globuli bianchi+DNA libero circolante nel plasma Patologia molecolare Plasma Punto nel tempo (episodio) Testo
zh-CN Chinese (China) 关于无创性产前胎儿非整倍体性风险的遗传咨询师意见:文本型属性:时间点:白细胞.DNA+血浆.cfDNA:叙述型:染色体特异性 cfDNA 剂量测定
Synonyms: WBC.DNA+血浆.cfDNA;白细胞.DNA 与血浆.cfDNA;白细胞.DNA+血浆循环 cfDNA;白细胞.DNA+血浆循环 DNA;白细胞.DNA+循环游离核酸;白细胞.DNA+血浆游离 DNA;白细胞.DNA+血浆无细胞 DNA WBC;WBCs;白血球;白血细胞 全面;整体;总体情况 关于无创性（无创型、无创、非侵入性）产前胎儿非整倍体性（非整倍体型、非整倍体、异倍体、非整倍性、异倍性、非整倍态、异倍体性）的遗传咨询师（遗传病辅导员、基因咨询师、遗传谘询师、基因谘询师）意见（评论、解释、注释、注解、点评） 分子病理学;分子病理学试验 叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型 备注 备注;评论;注解;说明;评语 意见 文本;文本型;文本属性 时刻;随机;随意;瞬间 染色体特异性 cf DNA 剂量测定;染色体特异性游离循环 DNA 剂量测定;染色体特异性循环游离 DNA 剂量测定;Cell Free DNA 注解 特异 特异性的 特异的 短评 血浆循环 cfDNA;血浆循环 DNA;循环游离核酸;血浆游离 DNA;血浆无细胞 DNA;Free circulating/Cell-free DNA;Free circulating DNA 解说 解释 评定 评注 评论 评语 说明

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CodeSystem lookup
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