96980-8

Comment on overall fetal aneuploidy risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative

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Part Description

LP422368-3 Comment on overall fetal aneuploidy risk
Noninvasive prenatal screening is used to assess fetal risk for various genetic conditions without requiring invasive maternal procedures such as amniocentesis or chorionic villus sampling. Cell-free DNA (cfDNA) in maternal plasma comes from both fetal and maternal sources, and various platforms have been developed using cfDNA to determine fetal risk. Natera's Panorama prenatal screening test uses a single blood sample from a pregnant woman, and using their proprietary informatics analysis method (NATUS), effectively subtracts the maternal genotype (from WBC DNA) from the cfDNA genotype and analyzes the remaining fetal cfDNA genotype for a variety of conditions including aneuploidy (e.g., Trisomy 21, Monosomy X) and microdeletions (e.g., 22q11.2 deletion). Specific results are typically reported for each individual condition and summarized for the report as a whole -- if the risk of any individual condition is high, the overall interpretation is "high risk," and if all the individual risks are low, the overall interpretation is "low risk." In addition, the genetic counselor who reviews the results may add specific interpretation details or follow-up recommendations to the report. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Comment on overall fetal aneuploidy risk:Txt:Pt:WBC.DNA+Plas.cfDNA:Nar:Dosage of chromosome specific cf DNA
Long Common Name: Comment on overall fetal aneuploidy risk [Text] in Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA Narrative
Short Name: Comment aneu risk WBC.DNA+cfDNA
Display Name: Comment on overall fetal aneuploidy risk Dosage of chromosome-specific cfDNA Nar (Plasma cell-free+WBC DNA)
Consumer Name Alpha Get Info: Comment on overall fetal aneuploidy risk

Part Model Get Info

Component
Comment on overall fetal aneuploidy risk
LP422368-3
- Analyte
  Comment on overall fetal aneuploidy risk
  LP422368-3
  - Component Numerator
    Comment on overall fetal aneuploidy risk
    LP422368-3
    - Component Numerator Core
      Comment on overall fetal aneuploidy risk
      LP422368-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Txt
LP6885-0
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
WBC.DNA+Plas.cfDNA
LP185797-0
- System Core
  WBC.DNA+Plas.cfDNA
  LP185797-0
- Super System
  NULL
Scale
Nar
LP7749-7
Method
Dosage of chromosome specific cf DNA
LP172871-8

Basic Attributes

Class: MOLPATH
Type: Laboratory
First Released: Version 2.70
Last Updated: Version 2.70 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
96977-4	Noninvasive prenatal fetal aneuploidy panel - Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Komentář Aneuploidie celkové riziko u plodu:Text:Časový bod:DNA volná cirkulující (cfDNA) a DNA leukocytů (WBC DNA):Narativní:Dávkování chromozomálně specifické cfDNA
el-GR	Greek (Greece)	Σχόλιο επί του συνολικού κινδύνου εμβρυϊκής ανευπλοειδίας:Txt:Pt:Αριθμός λευκών αιμοσφαιρίων.DNA+Πλάσμα.cfDNA:Nar:Δοσολογία ειδικού χρωμοσωμικού cf DNA Synonyms: MOLPATH Nar Pt Txt Αριθμός λευκών αιμοσφαιρίων Αριθμός λευκών αιμοσφαιρίων.DNA+Πλάσμα.cfDNA Δοσολογία ειδικού χρωμοσωμικού cf DNA Πλάσμα Πλάσμα.cfDNA Σχόλιο Σχόλιο επί του συνολικού κινδύνου εμβρυϊκής ανευπλοειδίας
es-ES	Spanish (Spain)	Comentario sobre el riesgo general de aneuploidía fetal:Texto:Punto temporal:ADN en plasma libre de células y leucocitos:Narrativo:Dosificación de ADN ccf de cromosoma específico
es-MX	Spanish (Mexico)	Comente sobre el riesgo general de aneuploidía fetal:TXT:Punto temporal:WBC.DNA + Plas.cfDNA:Narrativo:Dosificación de ADN cf cromosómico específico
fr-FR	French (France)	Risque global d'aneuploïdie foetale (Commentaire):Texte:Ponctuel:Leucocytes ADN+Plasma avec ADN libre circulant:Résultat textuel:Dosage d'ADN libre circulant spécifiques aux chromosomes
it-IT	Italian (Italy)	Commento su rischio generale aneuploidaia fetale:Txt:Pt:WBC.DNA+Plas.cfDNA:Nar:Dosaggio di DNA libero fetale circolante cromosoma specifico Synonyms: DNA libero circolante nel plasma Dosaggio di DNA libero fetale circolante cromosoma Globuli bianchi Globuli bianchi+DNA libero circolante nel plasma Patologia molecolare Plasma Punto nel tempo (episodio) Testo
zh-CN	Chinese (China)	关于无创性产前胎儿非整倍体性风险的遗传咨询师意见:文本型属性:时间点:白细胞.DNA+血浆.cfDNA:叙述型:染色体特异性 cfDNA 剂量测定 Synonyms: WBC.DNA+血浆.cfDNA;白细胞.DNA 与血浆.cfDNA;白细胞.DNA+血浆循环 cfDNA;白细胞.DNA+血浆循环 DNA;白细胞.DNA+循环游离核酸;白细胞.DNA+血浆游离 DNA;白细胞.DNA+血浆无细胞 DNA WBC;WBCs;白血球;白血细胞全面;整体;总体情况关于无创性（无创型、无创、非侵入性）产前胎儿非整倍体性（非整倍体型、非整倍体、异倍体、非整倍性、异倍性、非整倍态、异倍体性）的遗传咨询师（遗传病辅导员、基因咨询师、遗传谘询师、基因谘询师）意见（评论、解释、注释、注解、点评）分子病理学;分子病理学试验叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型备注备注;评论;注解;说明;评语意见文本;文本型;文本属性时刻;随机;随意;瞬间染色体特异性 cf DNA 剂量测定;染色体特异性游离循环 DNA 剂量测定;染色体特异性循环游离 DNA 剂量测定;Cell Free DNA 注解特异特异性的特异的短评血浆循环 cfDNA;血浆循环 DNA;循环游离核酸;血浆游离 DNA;血浆无细胞 DNA;Free circulating/Cell-free DNA;Free circulating DNA 解说解释评定评注评论评语说明

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.