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Term Description

Qualitative detection of nucleic acids within the beta-lactamase CTX-M-15 gene (blaCTX-M-15) found in Gram-negative bacteria. Testing may be performed in addition to conventional culture susceptibility testing to determine the potential bacterial resistance mechanism to antibiotics.

Part Description

LP426518-9   Bacterial beta-lactam resistance ESBL blaCTX-M-15 gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some bacteria that are resistant to the majority of beta-lactam antibiotics which include the penicillins, cephalosporins and the monobactam aztreonam. https://www.uptodate.com/contents/extended-spectrum-beta-lactamases Organisms producing CTX-M type ESBL enzymes have been isolated worldwide with more than 150 enzymes identified. These enzymes have been classified into seven major phylogenetic groups: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25, CTX-M-74 and CTX-M-75. CTX-M-9 group includes CTX-M-14 and CTX-M-15. The rare ESBL type CTX-M-8 has been isolated in Germany, mainly in E. coli, but also in Salmonella and E. aerogenes. CTX-M type ESBL have been isolated worldwide and their incidence has increased dramatically and is still increasing leading to a major therapeutic issue. Currently more than 150 allelic variants of CTX-M have been identified. The dissemination of these enzymes has caused an increased use of carbapenems for treatment of infections which carries its own risk of furthering resistance. PMID: 25234380 The genes are named with the prefix "bla", which stands for "beta-lactam", followed by the enzyme, for example, blaCTX-M-1. Source: LOINC

LOINC Names Get Info

Fully-Specified Name
Bacterial beta-lactam resistance ESBL blaCTX-M-15 gene:PrThr:Pt:Isolate/Specimen:Ord:Molgen
Long Common Name
Beta-lactam resistance ESBL blaCTX-M-15 gene [Presence] by Molecular method
Short Name
ESBL blaCTX-M-15 gene Islt/Spm Ql
Display Name
Beta-lactam resistance ESBL blaCTX-M-15 gene Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info
Beta-lactam resistance ESBL blaCTX-M-15 gene

Part Model Get Info

  • Component
    Bacterial beta-lactam resistance ESBL blaCTX-M-15 gene
    LP426518-9
    • Analyte
      Bacterial beta-lactam resistance ESBL blaCTX-M-15 gene
      LP426518-9
      • Component Numerator
        Bacterial beta-lactam resistance ESBL blaCTX-M-15 gene
        LP426518-9
        • Component Numerator Core
          Bacterial beta-lactam resistance ESBL blaCTX-M-15 gene
          LP426518-9
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Isolate/Specimen
    LP266970-5
    • System Core
      Isolate/Specimen
      LP266970-5
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Molgen
    LP6404-0

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.72 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gen blaCTX-M-15 bakteriální rezistence na beta-laktamy ESBL:Přítomnost nebo práh:Časový bod:Izolát/vzorek:Ordinální:Molekulární genetika
de-DEGerman (Germany)Bakterielle Beta-Lactam-Resistenz ESBL blaCTX-M-15-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch
Synonyms: Extended Spectrum beta-lactamases
el-GRGreek (Greece)Βακτηριακή ανθεκτικότητα στη β-λακτάμη γονίδιο ESBL blaCTX-M-15:PrThr:Pt:Απομονωθέν στέλεχος/Δείγμα:Ord:Μοριακή γενετική
Synonyms: ABXBACT M Ord PrThr Pt Απομονωθέν στέλεχος/Δείγμα Απομονωμένο στέλεχος Βακτηριακή ανθεκτικότητα στη β-λακτάμη γονίδιο ESBL blaCTX-M-15 Γονίδιο Δείγμα Μοριακή γενετική
es-ESSpanish (Spain)gen bacteriano ESBL blaCTX-M-15 resistente a betalactámicos:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MXSpanish (Mexico)Resistencia bacteriana a betalactámicos BLEE gen blaCTX-M-15:PrThr:Punto temporal:Aislar / Muestra:Ordinal:Molgen
fr-FRFrench (France)Résistance bactérienne aux bêta-lactamines gène ESBL blaCTX-M-15:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-ITItalian (Italy)Resistenza batterica beta-lactamica, gene ESBL blaCTX-M-15:PrThr:Pt:Isolato/Campione:Ord:Molgen
Synonyms: Gene ESBL blaCTX-M-15 di resistenza batterica beta-lactamica Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NLDutch (Netherlands)bacteriële bètalactamresistentie ESBL blaCTX-M-15-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
Synonyms: isolaat/specimen molgen
pl-PLPolish (Poland)Gen blaCTX-M-15 ESBL porności bakterii na beta-laktamy:granica wykrywalności:punkt w czasie:szczep/izolat lub próbka:uporządkowany:genetyka molekularna
Synonyms: diagnostyka molekularna
zh-CNChinese (China)细菌 beta-内酰胺耐药 ESBL blaCTX-M-15 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
Synonyms: B M 型 β 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分离株/标本（样本、样品、试样） 分离物;分离菌;分离菌株;隔离种群 受检物 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 抗力 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 样品 样本 电阻 细菌 beta-内酰胺（β-内酰胺）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） ESBL（超广谱β-内酰胺酶） blaCTX-M-15 基因 细菌性 细菌的 耐性 试样 贝塔 遗传基因;遗传因子;吉恩;生物基因 阻力

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=98063-1