98063-1
Beta-lactam resistance ESBL blaCTX-M-15 gene [Presence] by Molecular method
Active
Term Description
Qualitative detection of nucleic acids within the beta-lactamase CTX-M-15 gene (blaCTX-M-15) found in Gram-negative bacteria. Testing may be performed in addition to conventional culture susceptibility testing to determine the potential bacterial resistance mechanism to antibiotics.
Source: Regenstrief LOINC
Part Description
LP426518-9 Bacterial beta-lactam resistance ESBL blaCTX-M-15 gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some bacteria that are resistant to the majority of beta-lactam antibiotics which include the penicillins, cephalosporins and the monobactam aztreonam. [https://www.uptodate.com/contents/extended-spectrum-beta-lactamases] Organisms producing CTX-M type ESBL enzymes have been isolated worldwide with more than 150 enzymes identified. These enzymes have been classified into seven major phylogenetic groups: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25, CTX-M-74 and CTX-M-75. CTX-M-9 group includes CTX-M-14 and CTX-M-15. The rare ESBL type CTX-M-8 has been isolated in Germany, mainly in E. coli, but also in Salmonella and E. aerogenes. CTX-M type ESBL have been isolated worldwide and their incidence has increased dramatically and is still increasing leading to a major therapeutic issue. Currently more than 150 allelic variants of CTX-M have been identified. The dissemination of these enzymes has caused an increased use of carbapenems for treatment of infections which carries its own risk of furthering resistance. PMID: 25234380 The genes are named with the prefix "bla", which stands for "beta-lactam", followed by the enzyme, for example, blaCTX-M-1.
Source: LOINC
Fully-Specified Name
- Component
- Bacterial beta-lactam resistance ESBL blaCTX-M-15 gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- ESBL blaCTX-M-15 gene Islt/Spm Ql
- Display Name
- Beta-lactam resistance ESBL blaCTX-M-15 gene Molgen Ql (Islt/Spec)
- Consumer Name Alpha Get Info
- Beta-lactam resistance ESBL blaCTX-M-15 gene
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.70
- Last Updated
- Version 2.72
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Bakterielle Beta-Lactam-Resistenz ESBL blaCTX-M-15-Gen: Synonyms: Extended Spectrum beta-lactamases |
es-ES | Spanish (Spain) | gen bacteriano ESBL blaCTX-M-15 resistente a betalactámicos: |
es-MX | Spanish (Mexico) | Resistencia bacteriana a betalactámicos BLEE gen blaCTX-M-15: |
fr-FR | French (France) | Résistance bactérienne aux bêta lactamases ESBL blaCTX-M-15 gène: |
it-IT | Italian (Italy) | Resistenza batterica beta-lactamica, gene ESBL blaCTX-M-15: Synonyms: Gene ESBL blaCTX-M-15 di resistenza batterica beta-lactamica Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici |
nl-NL | Dutch (Netherlands) | bacteriële bètalactamresistentie ESBL blaCTX-M-15-gen: Synonyms: isolaat/specimen molgen |
zh-CN | Chinese (China) | 细菌 beta-内酰胺耐药 ESBL blaCTX-M-15 基因: Synonyms: B M 型 β 供检查用的材料; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=98063-1
Third Party Copyright
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