Colistin resistance mcr-3+mcr-4+mcr-5 genes [Presence] by Molecular method
Qualitative detection of nucleic acids within the mobilized colistin resistance (mcr) genes 3-5 (mcr-3, mcr-4, mcr-5) found in Gram-negative bacteria. Testing may be performed in addition to conventional culture susceptibility testing to determine the potential bacterial resistance mechanism to antibiotics.
Source: Regenstrief LOINC
LP426517-1 Bacterial colistin resistance mcr-3+mcr-4+mcr-5 genes
The mobilized colistin resistance genes (mcr-1 to mcr-5, and variants) are located on a plasmid within bacterial cells and affect the ability of antibiotics, including polymyxins and colistin, to bind to the bacteria. The mode of action of the antibiotics is to bind to the outer membrane of the phosphate group of lipid A lipopolysaccharide and to intercalate into the inner membrane forming pores that result in bacterial lysis. The polymyxins & colistin are the last line of defense used to treat multidrug resistant gram-negative bacteria so the emergence of the mcr genes in Enterobacteriaceae, including Klebsiella pneumoniae, is onerous and challenging to public health. PMID: 27893854 PMID: 29439754 Source: Regenstrief LOINC
- Bacterial colistin resistance mcr-3+mcr-4+mcr-5 genes
- Short Name
- Colistin res mcr-(3-5) Islt/Spm Ql
- Display Name
- Colistin resistance mcr-3+mcr-4+mcr-5 genes Molgen Ql (Islt/Spec)
- Consumer Name Alpha Get Info
- Colistin resistance mcr-3+mcr-4+mcr-5 genes
Example Answer List: LL2021-5Source: Gen-Probe
|PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)||LA6576-8|
|NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)||LA6577-6|
|InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value)||LA15841-2|
- First Released
- Version 2.70
- Last Updated
- Version 2.72
- Order vs. Observation
Language Variants Get Info
|de-DE||German (Germany)||Bakterielle Colistin-Resistenz mcr-3+mcr-4+mcr-5-Gene:
|es-ES||Spanish (Spain)||genes bacterianos mcr-3 + mcr-4 + mcr-5 resistentes a colistina:
|es-MX||Spanish (Mexico)||Resistencia a la colistina bacteriana genes mcr-3 + mcr-4 + mcr-5:
|fr-FR||French (France)||Bactérie mcr-3+mcr-4+mcr-5 gènes résistance à la colistine:
|it-IT||Italian (Italy)||Geni mcr-3+mcr-4+mcr-5 di resistenza batterica alla colistina:
Synonyms: Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
|nl-NL||Dutch (Netherlands)||bacteriële colistineresistentie mcr-3+mcr-4+mcr-5-genen:
Synonyms: isolaat/specimen molgen
|zh-CN||Chinese (China)||细菌粘菌素耐药 mcr-3+mcr-4+mcr-5 基因:
Synonyms: Ⅲ III 三 供检查用的材料;
LOINC Terminology Service (API) using
HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or firstname.lastname@example.org<mailto:email@example.com>. This may incur a fee in SNOMED International non-Member countries.
Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright