Version 2.77

Description

1-Hydroxymidazolam is an active metabolite of the drug midazolam (known by the brand names Dormicum, Hypnovel, and Versed). Although the metabolite is active, it is found in much smaller concentrations than the parent. Midazolam is metabolized by cytochrome C450 3A (CYP3A) primarily to 1-Hydroxymidazolam, but also in smaller amounts to 4-Hydroxymedazolam and also the 1,4 Dihydroxy form. Determining the conversion kinetics of midazolam has been proposed for CYP3A phenotyoing (Rapid Commun. Mass Spectrom. 2007; 21: 1531-1540). Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
1-Hydroxymidazolam
Part Type
Component (Describes the core component or analyte measured)
Created On
2010-04-26
Construct for LOINC Short Name
1OH-midazolam

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP100616-4

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 1-羟基咪达唑仑
Synonyms: 1-羟基咪哒唑仑
fr-CA French (Canada) 1-Hydroxymidazolam
et-EE Estonian (Estonia) 1-hüdroksümidasolaam
es-ES Spanish (Spain) 1-Hidroximidazolam
it-IT Italian (Italy) 1-Idrossimidazolam
tr-TR Turkish (Turkey) 1-Hidroksimidazolam
ru-RU Russian (Russian Federation) 1-гидроксимидазолам
nl-NL Dutch (Netherlands) 1-hydroxymidazolam
fr-BE French (Belgium) 1-Hydroxymidazolam