Version 2.78

Descriptions

Parechovirus is a viral genus in the family Picornaviridae and contains two species, Human parechovirus (HPeV) and Ljungan virus (LV). HPeVs cause various diseases, including aseptic meningitis, gastroenteritis, encephalitis, acute respiratory illness, and neonatal sepsis-like disease. LVs may be involved with diseases such as type 1 diabetes mellitus, myocarditis, and Guillain-Barre syndrome. Methods such as real-time reverse transcription-PCR (RT-PCR) are performed to detect members of the genus Parechovirus. Some RT-PCR assay can detect both HPeVs and LVs targeting the conserved regions in the 5' nontranslated region (5'NTR) of the parechovirus genome. Other assays target only known HPeVs or only LVs. Source: Regenstrief LOINC, PMID: 18524969

The Parechovirus belongs to the family Picornaviridae and is a small, nonenveloped RNA virus with icosahedral capsids. There are two species of Parechovirus including Parechovirus A (HPeV), previously named Human parechovirus, and Parechovirus B, previously named Ljungan virus. HPeV is made up of nineteen types designated as HPeV-1 to HPeV-19. Human infection by HPeV occurs worldwide and is often asymptomatic. Transmission of HPeV is by the fecal-oral route, respiratory secretions and fomites. When symptoms occur, they usually consist of mild gastroenteritis and respiratory symptoms. More serious disease has been attributed to HPeV-3, which can cause neonatal sepsis and aseptic meningitis in children. In 9 out of 10 neonates infected with HPeV-3, there is white matter damage which can lead to cerebral palsy, epilepsy and learning disabilities. There is no FDA approved anti-viral treatment for HPeV available, though there are some therapies in development that target viral capsid proteins, proteases and polymerase. [http://www.picornaviridae.com/parechovirus/parechovirus.htm][https://wwwnc.cdc.gov/eid/article/20/1/pdfs/13-0569.pdf Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Parechovirus
Part Type
Component (Describes the core component or analyte measured)
Created On
2010-08-23
Construct for LOINC Short Name
PeV

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 副肠孤病毒
Synonyms: 双埃柯病毒属;副肠孤病毒属;双埃柯病毒;双埃可病毒;Parechovirus;PeV;副腸孤病毒屬
es-ES Spanish (Spain) Parechovirus
it-IT Italian (Italy) Parechovirus
tr-TR Turkish (Turkey) Parechovirus
ru-RU Russian (Russian Federation) Парэховирус
nl-NL Dutch (Netherlands) Parechovirus
pl-PL Polish (Poland) Parechowirus
Synonyms: Ludzki parechowirus