Description

The International Scale (IS) was established in 2005 to standardize quantitative BCR-ABL1 measurements across tests and laboratories. (Hughes et al., Blood 2006). The IS is anchored to the baseline BCR-ABL1 expression level from the International Randomized Study of Interferon vs STI571 (IRIS) trial (100% IS) with a major molecular response (MMR) corresponding to 0.1% IS. (Hughes et al., N Engl J Med 2003). The IRIS trial and follow up studies have demonstrated that achieving MMR, or a 3-log reduction in BCR-ABL1 expression from the standardized baseline level, is a key clinical outcome. Percent ratios on the IS are obtained by multiplying the percent ratio (100 x BCR-ABL1/control gene) determined at local labs by a test-specific conversion factor (IS % ratio = local % ratio x conversion factor). Source: LOINC partner 1

Basic Part Properties

Part Name
control transcript (International Scale)
Part Display Name
control transcript (International Scale)
Part Type
Divisors (Divisors only)
Created On
2011-10-31
Construct for LOINC Short Name
Control (IS)

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP136109-8

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)对照转录物 (国际标尺)
Synonyms: 对照转录物(转录本、转录产物、转录子、转录);对照基因转录本;控制转录本;International Scale
es-ESSpanish (Spain)transcrito control (escala internacional)
it-ITItalian (Italy)trascritto di controllo (Scala Internazionale)
tr-TRTurkish (Turkey)kontrol transkripti (Uluslararası Ölçek)
ru-RURussian (Russian Federation)контроль транскрипция (Международная Шкала)
nl-NLDutch (Netherlands)controle transcript (internationale schaal)
fr-CAFrench (Canada)Transcrit de contrôle (échelle internationale)
fr-FRFrench (France)transcrit de référence (échelle internationale)
pl-PLPolish (Poland)kontrolny transkrypt (skala międzynarodowa)
el-GRGreek (Greece)μεταγραφή ελέγχου (Διεθνής Κλίμακα)
Synonyms: μεταγραφή ελέγχου (Διεθνής Κλίμακα)