LP136109-8
control transcript (International Scale)
Active
Description
The International Scale (IS) was established in 2005 to standardize quantitative BCR-ABL1 measurements across tests and laboratories. (Hughes et al., Blood 2006). The IS is anchored to the baseline BCR-ABL1 expression level from the International Randomized Study of Interferon vs STI571 (IRIS) trial (100% IS) with a major molecular response (MMR) corresponding to 0.1% IS. (Hughes et al., N Engl J Med 2003). The IRIS trial and follow up studies have demonstrated that achieving MMR, or a 3-log reduction in BCR-ABL1 expression from the standardized baseline level, is a key clinical outcome. Percent ratios on the IS are obtained by multiplying the percent ratio (100 x BCR-ABL1/control gene) determined at local labs by a test-specific conversion factor (IS % ratio = local % ratio x conversion factor). Source: LOINC partner 1
Basic Part Properties
- Part Display Name
- control transcript (International Scale)
- Part Type
- Divisors (Divisors only)
- Created On
- 2011-10-31
- Construct for LOINC Short Name
- Control (IS)
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP136109-8
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 对照转录物 (国际标尺) Synonyms: 对照转录物（转录本、 |
| es-ES | Spanish (Spain) | transcrito control (escala internacional) |
| it-IT | Italian (Italy) | trascritto di controllo (Scala Internazionale) |
| tr-TR | Turkish (Turkey) | kontrol transkripti (Uluslararası Ölçek) |
| ru-RU | Russian (Russian Federation) | контроль транскрипция (Международная Шкала) |
| nl-NL | Dutch (Netherlands) | controle transcript (internationale schaal) |
| fr-CA | French (Canada) | Transcrit de contrôle (échelle internationale) |
| pl-PL | Polish (Poland) | kontrolny transkrypt (skala międzynarodowa) |
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