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Treponema pallidum is a spirochaete bacterium. Pathogenic treponemes are classified based upon their clinical manifestations in humans: venereal syphilis, yaws, endemic syphilis and pinta. Nonpathogenic treponemes are often part of the normal flora of the genital tract, oral cavity or intestinal tract. Treponemal infections exhibit diverse clinical manifestations which are characterized by distinct clinical stages. Multiplication of the bacterium at the entry point causes the primary stage. Dissemination of treponemes to other tissues produces the second stage. After a latency period (up to 20 to 30 years), the tertiary stage develops. T. palladum subsp pallidum (venereal syphilis) is the most destructive subspecies and produces lesions in many bodily tissues including the central nervous system. Congenital syphilis may result in birth defects or fetal death. Venereal syphilis is sexually acquired except for congenital syphilis, which is transmitted to the fetus during the later stages of pregnancy. The other treponemes are acquired by close nonvenereal contact. Control of both venereal and nonvenereal disease is based upon surveillance and antibiotic treatment of contacts. [NCBI Books:NBK7716] Source: Regenstrief LOINC

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Syphilis

Basic Part Properties

Part Display Name
Treponema pallidum
Part Type
Component (Describes the core component or analyte measured)
Created On
Construct for LOINC Short Name
T pallidum

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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 梅毒螺旋体
Synonyms: 梅毒;苍白螺旋体;苍白密螺旋体
fr-CA French (Canada) Treponema pallidum
et-EE Estonian (Estonia) Treponema pallidum
es-ES Spanish (Spain) Treponema pallidum
it-IT Italian (Italy) Treponema pallidum
tr-TR Turkish (Turkey) Treponema pallidum
ru-RU Russian (Russian Federation) Treponema pallidum
nl-NL Dutch (Netherlands) Treponema pallidum
fr-BE French (Belgium) Treponema pallidum