Version 2.77

Description

Cardiolipin (bisphosphatidyl glycerol) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid. It is typically present in metabolically active cells of the heart and skeletal muscle. It has also been observed in certain bacterial membranes. It serves as an insulator and stabilizes the activity of protein complexes important to the electron transport chain. Cardiolipin is a double phospholipid because it has four fatty acid tails, instead of the usual two. Barth syndrome, a rare genetic disorder, is a mutation in the gene coding for tafazzin, an enzyme involved in the biosynthesis of cardiolipin. Females heterozygous for the trait are not affected. Individuals with this condition have abnormal mitochondria and they cannot sustain adequate production of ATP. Cardiomyopathy and general weakness are common to these patients. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Cardiolipin (Wikipedia)

Basic Part Properties

Part Display Name
Cardiolipin
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Cardiolipin

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14126-4

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 心磷脂
Synonyms: 双磷脂酰甘油;心肌磷脂
fr-CA French (Canada) Cardiolipine
et-EE Estonian (Estonia) Kardiolipiin
es-ES Spanish (Spain) Cardiolipinas
it-IT Italian (Italy) Cardiolipina
tr-TR Turkish (Turkey) Kardiyolipin
ru-RU Russian (Russian Federation) Кардиолипин
nl-NL Dutch (Netherlands) cardiolipine
fr-BE French (Belgium) Cardiolipine