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Cortisol establishes diagnosis of adrenocortical insufficiency, Addison's disease, Cushing's disease and other hypothalmic-pituitary adrenal cortex malfunctions. Testing interpretation is based on results from morning, afternoon, and evening specimens. Source: Regenstrief LOINC

Cortisol is a glucocorticoid produced in the adrenal cortex. A synthetic version of this same chemical is called hydrocortisone and manufactured as medication. Cortisol is not to be confused with cortisone, a closely related compound with much less (PubChem calls it "inactive") biologic activity. Cortisone is also offered as a drug, and it is converted to cortisol (the active form) in the liver. They both have a circadian rhythm with peak in the AM (around 8AM) and trough in the evening (around midnight), but this shifts according to sleep habits (work shifts). The morning measurement, which should be high, is most useful for diagnosing Addison's disease (too little cortisol) and the evening measurement, which should be low, is the most useful for diagnosing Cushing's disease (too much cortisol). Salivary cortisol may be a more sensitive measure than serum or plasma. Source: Regenstrief Help

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Tag Language Translation
zh-CN Chinese (China) 皮质醇
Synonyms: 17-羟皮质甾酮;17-羟皮质酮;化合物 F;可的索;氢化可的松;皮质甾醇;考的索
fr-CA French (Canada) Cortisol
et-EE Estonian (Estonia) Kortisool
es-ES Spanish (Spain) Cortisol
it-IT Italian (Italy) Cortisolo
el-GR Greek (Greece) Κορτιζόλη
tr-TR Turkish (Turkey) Kortizol
ru-RU Russian (Russian Federation) Кортизол
nl-NL Dutch (Netherlands) cortisol
fr-BE French (Belgium) Cortisol