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Cefaclor, also known as cefachlor, (brand names Ceclor®, Distaclor®, Keflor®, Raniclor®) is a 2nd-generation cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, Cefaclor (Wikipedia)

Semisynthetic, broad-spectrum antibiotic derivative of CEPHALEXIN. Source: National Library of Medicine, MeSH 2006

Cefaclor is a semisynthetic β-lactam antibiotic drug belonging to the cephalosporin subgroup. Like all β-lactams, cefaclor readily reacts with tissue proteins in vivo, thereby sensitizing susceptible individuals. The allergenic determinants (epitopes) of cephalosporins such as cefaclor are not fully known. This is a consequence of the unstable structures which are formed upon reaction with lysine amino groups in proteins. The primary unstable conjugates are rapidly degraded and transformed into structures where the six-membered dihydrothiazine ring is absent.

Immediate reactions (maximum 1 hour after drug intake) have the highest probability of being IgE-mediated. Clinical pictures typical for immediate reactions to β-lactams are urticaria, with or without angioedema, and anaphylaxis. Copyright Copyright © 2006 Phadia AB. Source: ImmunoCap, ImmunoCap

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Tag Language Translation
zh-CN Chinese (China) 氯氨苄青霉素
Synonyms: 头孢克罗;氯头孢菌素;氯氨下头孢菌素
fr-CA French (Canada) Céfaclor
et-EE Estonian (Estonia) Tsefakloor
es-ES Spanish (Spain) Cefaclor
it-IT Italian (Italy) Cefaclor
tr-TR Turkish (Turkey) Sefaklor
ru-RU Russian (Russian Federation) Цефаклор
nl-NL Dutch (Netherlands) cefaclor
fr-BE French (Belgium) Céfaclor