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Mycophenolic acid (MPA) or mycophenolate is an immunosuppressant drug used to prevent rejection after solid-organ transplant as well as graft-vs-host disease prophylaxis after hematopoietic stem cell transplant. MPA is highly bound to albumin and the unbound fraction of MPA is approximately 1−3% of the total. MPA is glucuronidated in the liver, primarily to an inactive metabolite, mycophenolic acid glucuronide, and partially to an active metabolite, mycophenolic acid acyl-glucuronide. Drug levels of MPA and its metabolites are used to adjust drug dosing and monitor patient adherence. MPA is commonly marketed under the trade names CellCept (mycophenolate mofetil; Roche) and Myfortic (mycophenolate sodium; Novartis). PMID: 25624121 Source: Regenstrief LOINC, PMID: 25624121

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Tag Language Translation
zh-CN Chinese (China) 吗替麦考酚酯
Synonyms: 霉酚酸;霉酚酸吗啉乙酯;霉酚酸酯
fr-CA French (Canada) Mycophénolate
et-EE Estonian (Estonia) Mükofenoolhape
es-ES Spanish (Spain) Micofenolato
it-IT Italian (Italy) Micofenolato
tr-TR Turkish (Turkey) Mikofenolat
ru-RU Russian (Russian Federation) Микофенолат
nl-NL Dutch (Netherlands) mycofenolaat
fr-BE French (Belgium) Mycophénolate