Version 2.78

Descriptions

Androstenedione (also known as 4-androstenedione) is a 19-carbon steroid hormone produced in the adrenal glands and the gonads as an intermediate step in the biochemical pathway that produces the androgen testosterone and the estrogens estrone and estradiol. It is the common precursor of male and female sex hormones. Some androstenedione is also secreted into the plasma, and may be converted in peripheral tissues to testosterone and estrogens. Androstenedione originates either from the conversion of dehydroepiandrosterone or from 17-hydroxyprogesterone. It is further converted to either testosterone or estrone. The production of adrenal androstenedione is governed by ACTH, while production of gonadal androstenedione is controled by gonadotropins. In premenopausal women the adrenal glands and ovaries each produce about half of the total androstendione (about 3 mgday). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Androstenedione (Wikipedia)

Androstenedione is a delta-4 C19 steroid produced in the testis, ovary and adrenal cortex. Depending on the tissue type, androstenedione can serve as a precursor to testosterone or to estrone and estradiol. Source: National Library of Medicine, MeSH 2006

Testing for androstenedione is used to diagnose viralizing syndromes including congenital adrenal hyperplasia, female virilization, hirsutism, polycystic ovarian disease, Stein-Levethal syndrome. and to detect abuse of anabolic steroids. It is also a drug- an anabolic steroid- used to enhance atheletic performance, but banned as an OTC drug by the FDA in 2004. Source: Regenstrief Institute

Basic Part Properties

Part Display Name
Androstenedione
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Androst

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 雄烯二酮
Synonyms: Androst;gamma-4-雄烯二酮;gamma-4-雄甾烯二酮;γ-4-雄烯二酮;γ-4-雄甾烯二酮;雄甾烯二酮
fr-CA French (Canada) Androstènedione
et-EE Estonian (Estonia) Androsteendioon
es-ES Spanish (Spain) Androstenediona
it-IT Italian (Italy) Androstenedione
tr-TR Turkish (Turkey) Androstenediyon
ru-RU Russian (Russian Federation) Андростендион
nl-NL Dutch (Netherlands) androsteendion
fr-BE French (Belgium) Androstènedione