Version 2.77

Descriptions

Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the placenta. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized. Source: National Library of Medicine, MeSH 2006

Estradiol, derived from the ovary, testis, and placenta, may be the most biologically active estrogen. It is measured in the serum to evaluate hypogonadotropic and hypoestrogenic causes of menstrual abnormalities, sexual immaturity in females, estrogen-producing tumors, and feminization in males. Estrogens are increased in liver cirrhosis and depressed in Turner's syndrome. Ingestion of estrogens, such as oral contraceptives, increases the serum levels. Source: Regenstrief Institute

Basic Part Properties

Part Display Name
Estradiol
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Estradiol

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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 雌二醇
Synonyms: 17-Beta 雌二醇;17-β雌二醇;E2;Oestradiol;雌甾二醇
fr-CA French (Canada) Estradiol
et-EE Estonian (Estonia) Östradiool
es-ES Spanish (Spain) Estradiol
it-IT Italian (Italy) Estradiolo
el-GR Greek (Greece) Οιστραδιόλη
tr-TR Turkish (Turkey) Östradiyol
ru-RU Russian (Russian Federation) Эстрадиол
nl-NL Dutch (Netherlands) oestradiol
fr-BE French (Belgium) Estradiol