LP14517-4
Phenylpropionylglycine
Active
Description
Phenylpropionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13), which is an enzyme that catalyzes the chemical reaction:acyl-CoA + glycine < -- > CoA + N-acylglycine. The detection of phenylpropionylglycine in urine after an oral load of phenylpropionic acid can be used to diagnose deficiency of medium-chain acyl-CoA dehydrogenase, a frequent and treatable metabolic defect. PMID: 9234867 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Phenylpropionylglycine
Basic Part Properties
- Part Display Name
- Phenylpropionylglycine
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- PPG
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 苯丙酰甘氨酸 Synonyms: PPG |
| fr-CA | French (Canada) | Phénylpropionylglycine |
| et-EE | Estonian (Estonia) | Fenüülpropionüülglütsiin |
| es-ES | Spanish (Spain) | Fenilpropionilglicina |
| it-IT | Italian (Italy) | Fenilpropionilglicina |
| tr-TR | Turkish (Turkey) | Fenilpropiyonilglisin |
| ru-RU | Russian (Russian Federation) | Фенилпропионилглицин |
| nl-NL | Dutch (Netherlands) | fenylpropionylglycine |
| fr-BE | French (Belgium) | Phénylpropionylglycine |
| pl-PL | Polish (Poland) | Fenylopropionyloglicyna |
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