LP14535-6
F little y super little a
Active
Description
The Duffy glycoprotein is a receptor that binds cytokines released during inflammation. It also binds the malaria parasite Plasmodium vivax, and RBCs that lack the Duffy Fy^a and Fy^b antigens are resistant to invasion. Structurally, the Duffy protein is similar to the family of G-protein coupled receptors, having 7 transmembrane domains. FY has two major codominant alleles, FYA and FYB, which result from a SNP (125G→A), and the corresponding Fy^a and Fy^b antigens differ by a single amino acid (G42D). Individuals who are homozygous for a -33T→C SNP in the erythroid promoter region of the FYB allele have the phenotype Fy(a-b-) and do not express Duffy antigens on their RBCs. Beck L, Blood groups and red cell antigens. NCBI Bookself [Internet Book], 2005. Source: National Library of Medicine, Fy^a
Basic Part Properties
- Part Display Name
- Fy^a
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Fy sup(a)
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | Fy^a Synonyms: F little y super little a |
| fr-CA | French (Canada) | F petit y exposant petit a |
| et-EE | Estonian (Estonia) | Fy^a |
| es-ES | Spanish (Spain) | Fya |
| it-IT | Italian (Italy) | F y minuscola apice a Synonyms: Fy^a |
| tr-TR | Turkish (Turkey) | F küçük y süper küçük a |
| ru-RU | Russian (Russian Federation) | F малое y супер малое a |
| nl-NL | Dutch (Netherlands) | F kleine y super kleine a Synonyms: Fy^a |
| fr-BE | French (Belgium) | F petit y exposant petit a |
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