LP14546-3
Barbiturates
Active
Description
Barbiturates are CNS depressants that primarily act on gamma-aminobutyric acid (GABA) and GABA A receptors. When GABA binds to GABA A, chloride channels open and allow the influx of chloride ions, which decrease the membrane potential and inhibit the neuron's action potential. They are used as sedatives, hypnotics, anesthetics, and anticonvulsants. Prolonged use can lead to physical tolerance and dependence, which has caused a significant decrease in their use over time. However, certain uses are still common, such as phenobarbital for refractory seizure disorders, butalbital for analgesia, and thiopental for anesthesia. PMID: 25824249 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Barbiturates
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Barbiturates
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 巴比妥类药物 Synonyms: 巴比土酸盐(酯); |
| fr-CA | French (Canada) | Barbituriques |
| et-EE | Estonian (Estonia) | Barbituraadid |
| es-ES | Spanish (Spain) | Barbituratos |
| it-IT | Italian (Italy) | Barbiturici |
| tr-TR | Turkish (Turkey) | Barbitüratlar |
| ru-RU | Russian (Russian Federation) | Барбитураты |
| nl-NL | Dutch (Netherlands) | barbituraten |
| fr-BE | French (Belgium) | Barbituriques |
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