Version 2.77

Description

Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic. It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole, which is also known as Bactrim or Septrin. It can be used as an alternative to amoxicillin -based antibiotics to treat sinusitis. Mechanism of action:Sulfonamides are structural anologs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Sulfamethoxazole (Wikipedia)

Basic Part Properties

Part Display Name
Sulfamethoxazole
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Sulfamethoxazole

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14550-5
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP14550-5

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 磺胺甲噁唑
Synonyms: SMX;SMZ;新明磺;新诺明;磺胺甲噁唑;磺胺甲基异噁唑;磺胺甲基异恶唑;磺胺甲异唑;磺胺甲恶唑
fr-CA French (Canada) Sulfaméthoxazole
et-EE Estonian (Estonia) Sulfametoksasool
es-ES Spanish (Spain) Sulfametoxazol
it-IT Italian (Italy) Sulfametossazolo
tr-TR Turkish (Turkey) Sulfametoksazol
ru-RU Russian (Russian Federation) Сульфаметоксазол
nl-NL Dutch (Netherlands) sulfamethoxazol
fr-BE French (Belgium) Sulfaméthoxazole