Version 2.77


Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic. It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole, which is also known as Bactrim or Septrin. It can be used as an alternative to amoxicillin -based antibiotics to treat sinusitis. Mechanism of action:Sulfonamides are structural anologs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, Sulfamethoxazole (Wikipedia)

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Tag Language Translation
zh-CN Chinese (China) 磺胺甲噁唑
Synonyms: SMX;SMZ;新明磺;新诺明;磺胺甲噁唑;磺胺甲基异噁唑;磺胺甲基异恶唑;磺胺甲异唑;磺胺甲恶唑
fr-CA French (Canada) Sulfaméthoxazole
et-EE Estonian (Estonia) Sulfametoksasool
es-ES Spanish (Spain) Sulfametoxazol
it-IT Italian (Italy) Sulfametossazolo
tr-TR Turkish (Turkey) Sulfametoksazol
ru-RU Russian (Russian Federation) Сульфаметоксазол
nl-NL Dutch (Netherlands) sulfamethoxazol
fr-BE French (Belgium) Sulfaméthoxazole