Found on mature B-cells. Expressed at the time of Ig light chain gene rearrangement.
Associated with some B-cell ALL and most mature B-cell neoplasms.
Usually absent in plasma cell neoplasms Source: Regenstrief Institute
CD20 is a non-glycosylated phosphoprotein expressed on the surface of all mature B-cells.
Membrane-spanning 4-domains, subfamily A, member 1, also known as MS4A1, is a human gene.
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD20
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