LP14625-5
CD34
Active
Descriptions
Found on immature hematopoietic cells
Associated with many acute leukemias - Not lineage specific
Source: Regenstrief Institute
CD 34+ cells can regenerate the bone marrow after transplant. Source: Regenstrief Institute
CD34 molecule is a cluster of differentiation molecule present on certain cells within the human body. It is a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells to bone marrow extracellular matrix or directly to stromal cells. CD34 is also the name for the human gene that encodes the protein. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD34
Normal bone marrows contain a small percent of cells carrying the CD34 antigen. Such cells can also be detected in the circulating blood and their numbers can be increased with the various marrow stimulating factors. It is a very important cell type for patients under consideration for bone marrow transplant because these cells include the hematopoetic stem cells needed to re-generate the bone marrow after it is ablated. The number of circulating CD34 is also useful in the diagnosis of myeloproliferative disorders and predicting which will transform to malignancy. Viable CD34 cells can be distinguished from dead ones with 7-AAD viability dye. Source: Regenstrief Help
Basic Part Properties
- Part Display Name
- CD34
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- CD34
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP14625-5
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CD34 Synonyms: gp105-120; |
| fr-CA | French (Canada) | CD34 |
| et-EE | Estonian (Estonia) | CD34 |
| es-ES | Spanish (Spain) | CD34 |
| it-IT | Italian (Italy) | CD34 |
| tr-TR | Turkish (Turkey) | CD34 |
| ru-RU | Russian (Russian Federation) | CD34 |
| nl-NL | Dutch (Netherlands) | CD34 |
| fr-BE | French (Belgium) | CD34 |
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