Version 2.77


Proinsulin is a protein encoded by the INS gene and a precursor to insulin. Proinsulin is a single chain of amino acids that is cleaved into three peptides. The three peptides include the A chain, B chain, and C-peptide. When the A and B chains are joined by a disulfide bond they become the hormone insulin. Insulin binds to the insulin receptors (INSR) on cells in the body to stimulate the uptake of glucose. In addition to decreasing the level of glucose in the blood, insulin also increases the permeability of cells to amino and fatty acids, and accelerates glycolysis and glycogen synthesis in the liver.[] Source: Regenstrief LOINC

Basic Part Properties

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Part Type
Component (Describes the core component or analyte measured)
Created On
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 胰岛素原
Synonyms: 前胰岛素;胰岛素前体
fr-CA French (Canada) Proinsuline
et-EE Estonian (Estonia) Proinsuliin
es-ES Spanish (Spain) Proinsulina
it-IT Italian (Italy) Proinsulina
tr-TR Turkish (Turkey) Proinsülin
ru-RU Russian (Russian Federation) Проинсулин
nl-NL Dutch (Netherlands) pro-insuline
fr-BE French (Belgium) Proinsuline