LP14654-5
Chymotrypsin
Active
Descriptions
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that can perform proteolysis. Chymotrypsin cleaves peptides at the carboxyl side of tyrosine, tryptophan, and phenylalanine, although over time it also hydrolyzes other amide bonds, particularly those with leucine -donated carboxyls. Activation of chymotrypsin:Chymotrypsin is synthesized in the pancreas by protein biosynthesis as a precursor called chymotrypsinogen that is enzymatically inactive. On cleavage by trypsin into two parts that are still connected via an S-S bond, cleaved chymotrypsinogen molecules can activate each other by removing two small peptides in a trans -proteolysis. The resulting molecule is active chymotrypsin, a three polypeptide molecule interconnected via disulfide bonds. Action and Kinetics of chymotrypsin:In vivo, chymotrypsin is a proteolytic enzyme acting in the digestive systems of mammals and other organisms. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Chymotrypsin (Wikipedia)
A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side. Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Display Name
- Chymotrypsin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Chymotryp
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 胰凝乳蛋白酶 Synonyms: 凝乳酶原; |
| fr-CA | French (Canada) | Chymotrypsine |
| et-EE | Estonian (Estonia) | Kümotrüpsiin |
| es-ES | Spanish (Spain) | Quimotripsina |
| it-IT | Italian (Italy) | Chimotripsina |
| tr-TR | Turkish (Turkey) | Kimotripsin |
| ru-RU | Russian (Russian Federation) | Химотрипсин |
| nl-NL | Dutch (Netherlands) | chymotrypsine |
| fr-BE | French (Belgium) | Chymotrypsine |
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