LP14659-4
Eosinophil major basic protein
Active
Descriptions
One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil major basic protein is a 14-kDa cytotoxic peptide with a pI of 10.9. In addition to its direct cytotoxic effects, it stimulates the release of variety of INFLAMMATION MEDIATORS. Source: National Library of Medicine, MeSH 2006
Proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein), also known as PRG2, is a protein which in humans is encoded by the PRG2 gene.
PRG2 is a 117-residue protein that predominates in eosinophil granules. It is a potent enzyme against helminths and is toxic towards bacteria and mammalian cells in vitro. The eosinophil major basic protein also causes the release of histamine from mast cells and basophils, activates neutrophils and alveolar macrophages, and is directly implicated in epithelial cell damage, exfoliation and bronchospasm in asthma.
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Source: Wikipedia, Wikipedia
Basic Part Properties
- Part Display Name
- Eosinophil major basic protein
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- EMBP
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 嗜酸性粒细胞主要碱性蛋白 Synonyms: EMBP; |
| fr-CA | French (Canada) | Protéine basique majeure des éosinophiles |
| es-ES | Spanish (Spain) | Proteína mayor básica del eosinófilo |
| it-IT | Italian (Italy) | Eosinofili, proteina basica maggiore Synonyms: Proteina basica maggiore (MBP) degli eosinofili |
| tr-TR | Turkish (Turkey) | Eozinofil major bazik protein |
| ru-RU | Russian (Russian Federation) | Эозинофилов большой основной протеин |
| nl-NL | Dutch (Netherlands) | eosinofiel major basic proteïne |
| fr-BE | French (Belgium) | Protéine basique majeure des éosinophiles |
| pl-PL | Polish (Poland) | Eozynofil, główne białko zasadowe Synonyms: Główne białko zasadowe granulocytów kwasochłonnych |
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