LP14685-9
Myelin basic protein
Active
Description
Myelin basic protein (MBP) is important in the process of myelination of nerves in the central nervous system (CNS). MBP was initially sequenced in 1979 after isolation from myelin membranes. Since that time, knockout mice deficient in MBP have been developed which showed decreased amounts of CNS myelination and a progressive disorder characterized by tremors, seizures, and early death. The gene for MBP is on chromosome 18; the protein localizes to the CNS and to various cells of the hematopoietic system. The pool of MBP in the central nervous system is very diverse, with several splice variants being expressed and a large number of post-translational modifications on the protein, which include phosphorylation, methylation, deamidation and citrullination. Interest in MBP has centered on its role in demyelinating diseases, particularly multiple sclerosis (MS). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Myelin basic protein (Wikipedia)
Basic Part Properties
- Part Name
- Myelin basic protein
- Part Display Name
- Myelin basic protein
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- MBP
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 髓磷脂碱性蛋白 Synonyms: MBP; |
| fr-CA | French (Canada) | Protéine basique de la myéline |
| es-ES | Spanish (Spain) | Proteína básica de la mielina |
| it-IT | Italian (Italy) | Mielina, proteina basica Synonyms: Proteina basica della mielina |
| tr-TR | Turkish (Turkey) | Miyelin bazik protein |
| ru-RU | Russian (Russian Federation) | Миелина основной протеин Synonyms: Миелина основной белок |
| nl-NL | Dutch (Netherlands) | myeline basic proteïn |
| fr-BE | French (Belgium) | Protéine basique de la myéline |
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