LP14693-3
Serotonin
Active
Descriptions
Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract. In the central nervous system, serotonin is believed to play an important role in the regulation of mood, sleep, emesis (vomiting), sexuality and appetite. Low levels of Serotonin have been associated with several disorders, notably depression, migraine, bipolar disorder and anxiety. Isolated and named in 1948 by Maurice M. Rapport, the name serotonin is something of a misnomer and reflects the circumstances of the compound's discovery. It was initially identified as a vasoconstrictor substance in blood serum hence serotonin, a serum agent affecting vascular tone. This agent was later chemically identified as 5-hydroxytryptamine (5-HT) by Rapport, and, as the broad range of physiological roles were elucidated, 5-HT became the preferred name in the pharmacological field. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Serotonin (Wikipedia)
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator. Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Display Name
- Serotonin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Serotonin
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 5-羟色胺 Synonyms: 5-HT; |
| fr-CA | French (Canada) | Sérotonine |
| et-EE | Estonian (Estonia) | Serotoniin |
| es-ES | Spanish (Spain) | Serotonina |
| it-IT | Italian (Italy) | Serotonina |
| tr-TR | Turkish (Turkey) | Serotonin |
| ru-RU | Russian (Russian Federation) | Серотонин |
| nl-NL | Dutch (Netherlands) | serotonine |
| fr-BE | French (Belgium) | Sérotonine |
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