LP14700-6
Vimentin
Active
Descriptions
An intermediate filament protein found in most differentiating cells, in cells grown in tissue culture, and in certain fully differentiated cells. Its insolubility suggests that it serves a structural function in the cytoplasm. MW 52,000. Source: National Library of Medicine, MeSH 2006
Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins are found in all metazoan cells as well as bacteria. IF, along with tubulin-based microtubules and actin-based microfilaments, comprise the cytoskeleton. All IF proteins are expressed in a highly developmentally-regulated fashion; vimentin is the major cytoskeletal component of mesenchymal cells. Because of this, vimentin is often used as a marker of mesenchymally-derived cells or cells undergoing an epithelial-to-mesenchymal transition (EMT) during both normal development and metastatic progression.
It has been used as a sarcoma tumor marker to identify mesenchyme.
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Source: Wikipedia, Wikipedia
Basic Part Properties
- Part Display Name
- Vimentin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Vimentin
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 波形蛋白 Synonyms: 弹性蛋白; |
| fr-CA | French (Canada) | Vimentine |
| et-EE | Estonian (Estonia) | Vimentiin |
| es-ES | Spanish (Spain) | Vimentina |
| it-IT | Italian (Italy) | Vimentina |
| tr-TR | Turkish (Turkey) | Vimentin |
| ru-RU | Russian (Russian Federation) | Виментин |
| nl-NL | Dutch (Netherlands) | vimentine |
| fr-BE | French (Belgium) | Vimentine |
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