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An intermediate filament protein found in most differentiating cells, in cells grown in tissue culture, and in certain fully differentiated cells. Its insolubility suggests that it serves a structural function in the cytoplasm. MW 52,000. Source: National Library of Medicine, MeSH 2006

Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins are found in all metazoan cells as well as bacteria. IF, along with tubulin-based microtubules and actin-based microfilaments, comprise the cytoskeleton. All IF proteins are expressed in a highly developmentally-regulated fashion; vimentin is the major cytoskeletal component of mesenchymal cells. Because of this, vimentin is often used as a marker of mesenchymally-derived cells or cells undergoing an epithelial-to-mesenchymal transition (EMT) during both normal development and metastatic progression.

It has been used as a sarcoma tumor marker to identify mesenchyme. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, Wikipedia

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Tag Language Translation
zh-CN Chinese (China) 波形蛋白
Synonyms: 弹性蛋白;波形丝蛋白;Vimentin;VIM
fr-CA French (Canada) Vimentine
et-EE Estonian (Estonia) Vimentiin
es-ES Spanish (Spain) Vimentina
it-IT Italian (Italy) Vimentina
tr-TR Turkish (Turkey) Vimentin
ru-RU Russian (Russian Federation) Виментин
nl-NL Dutch (Netherlands) vimentine
fr-BE French (Belgium) Vimentine