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Dipyridamole is a drug that inhibits platelet aggregation and causes vasodilation. It inhibits the cellular reuptake of adenosine into platelets, red blood cells and endothelial cells leading to increased extracellular concentrations of adenosine.It also inhibits the enzyme adenosine deaminase which normally breaks down adenosine into inosine. This inhibition leads to further increased levels of extracellular adenosine.Dipyridamole also inhibits the enzyme phosphodiesterase which normally breaks down cAMP.Adenosine interacts with the adenosine receptors to cause increased cAMP via adenylate cyclase.cAMP impairs platelet aggregation and also causes arteriolar smooth muscle relaxation.Modified release dipyridamole is used in conjunction with aspirin (under the trade name Aggrenox ®) in the secondary prevention of stroke and transient ischemic attack. This practice is now confirmed by the ESPRIT trial. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, Dipyridamole (Wikipedia)

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Tag Language Translation
zh-CN Chinese (China) 潘生丁
Synonyms: 双嘧哌胺醇;迪普莱达莫
fr-CA French (Canada) Dipyridamole
et-EE Estonian (Estonia) Dipüridamool
es-ES Spanish (Spain) Dipiridamol
it-IT Italian (Italy) Dipiridamolo
tr-TR Turkish (Turkey) Dipiridamol
ru-RU Russian (Russian Federation) Дипиридамол
nl-NL Dutch (Netherlands) dipyridamol
fr-BE French (Belgium) Dipyridamole