LP14914-3
Pyridinoline
Active
Description
Pyridinoline is a fluorescent cross-linking compound of collagen fibers. Crosslinks in collagen and elastin are derived from lysyl and hydroxylysyl residues, a process catalyzed by lysyl oxidase. Fujimoto and colleagues first described the isolation and characterization of a fluorescent material in bovine achilles tendon collagen and termed it pyridinoline. It is reported to be present in collagen of bone and cartilage, but is absent in collagen of skin. It is not present in newly synthesized collagen and is formed from aldimine cross-links during maturation of collagen fibers.
Pyridinoline and deoxypyridinoline were found to be released into the blood during bone degradation and rapidly exereted in the urine. In a preliminary study, both these compounds were proposed as a marker for metastatic bone tumor in patients with prostate cancer.
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Source: Wikipedia, Wikipedia
Basic Part Properties
- Part Display Name
- Pyridinoline
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- PYD
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 吡啶啉 Synonyms: 吡啶诺林; |
fr-CA | French (Canada) | Pyridinoline |
et-EE | Estonian (Estonia) | Püridinoliin |
es-ES | Spanish (Spain) | Piridinolina |
it-IT | Italian (Italy) | Piridinolina |
tr-TR | Turkish (Turkey) | Piridinolin |
ru-RU | Russian (Russian Federation) | Пиридинолин |
nl-NL | Dutch (Netherlands) | pyridinoline |
fr-BE | French (Belgium) | Pyridinoline |
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