Version 2.77

Description

Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Sequencing
Part Type
Method (Describes the method by which the test was performed)
Created On
2012-05-07
Construct for LOINC Short Name
Seq

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP150045-5

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 序列测定
Synonyms: 序列分析;测序
fr-CA French (Canada) Séquençage
es-ES Spanish (Spain) Secuenciación
it-IT Italian (Italy) Sequenziamento
tr-TR Turkish (Turkey) Sekanslama
Synonyms: Dizi tayini
nl-NL Dutch (Netherlands) sequencing
fr-BE French (Belgium) Séquençage
pl-PL Polish (Poland) sekwencjonowanie