LP15010-9
Trimethoprim
Active
Descriptions
Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections. It belongs to the class of chemotherapeutic agents known as dihydrofolate reductase inhibitors. Trimethoprim is marketed under the trade name Primsol. In clinical use it is often abbreviated TRI or TMP; its common laboratory abbreviation is W. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trimethoprim (Wikipedia)
A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported. Source: National Library of Medicine, MeSH 2006
Trimethoprim is a synthetic (man-made) antibiotic that interferes with the production of tetrahydrofolic acid, a chemical necessary in protein production. The drug inhibits the enzyme responsible for making tetrahydrofolic acid from dihydrofolic acid. Trimethoprim inhibits the bacterial enzyme more than the corresponding human enzyme, so it has less effect on the production of tetrahydrofolic acid by humans. It is effective against a wide variety of bacteria. Information is from MedicineNet.com, accessed 2006 10 16. Copyright Copyright © 1996-2008 MedicineNet, Inc. All rights reserved. Source: MedicineNet.com
Basic Part Properties
- Part Display Name
- Trimethoprim
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Trimethoprim
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 三甲氧苄二氨嘧啶 Synonyms: 三甲氧下二氨嘧啶; |
| fr-CA | French (Canada) | Triméthoprime |
| et-EE | Estonian (Estonia) | Trimetopriim |
| es-ES | Spanish (Spain) | Trimetoprim |
| it-IT | Italian (Italy) | Trimetoprim |
| tr-TR | Turkish (Turkey) | Trimetoprim |
| ru-RU | Russian (Russian Federation) | Триметоприм |
| nl-NL | Dutch (Netherlands) | trimethoprim |
| fr-BE | French (Belgium) | Triméthoprime |
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