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All immunoglobulins contain two polypeptide chains: a long (heavy) and a short (light) chain. The two chains interact via disulfide bonds. There are two types of light chains, named kappa and lambda. Serum free light chain (SFLC) testing, a kappa/lambda ratio and a protein electrophoresis test are done to help detect, diagnose and monitor plasma cell disorders (dyscrasias) including multiple myeloma and primary amyloidosis. Normal readings are seen when there is a kappa/lambda ratio of approximately 0.26 to 1.65 and free light chains are present in the blood at low levels. Increased kappa free light chains and an increased kappa/lambda ratio are present with plasma cell disorders that produce excess monoclonal kappa light chains. The tests can also be used to monitor response to treatment. An increase in serum free light chains along with an abnormal kappa/lambda ratio may indicate primary amyloidosis; biopsy of affected tissue is typically used for confirmation of diagnosis. PMID: 6802926 ] [Lab Tests Online:free-light/tab/test] Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Lambda light chains
Part Type
Component (Describes the core component or analyte measured)
Created On
Construct for LOINC Short Name
Lambda LC

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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 免疫球蛋白轻链.Lambda 型
Synonyms: Lambda LC;Lambda 型免疫球蛋白轻链;Lambda 型轻链;Lambda 轻链;λ型免疫球蛋白轻链;λ型轻链;λ轻链;免疫球蛋白轻链.Lambda;免疫球蛋白轻链.λ型;轻链.Lambda;轻链.Lambda 型;轻链.λ;轻链.λ型
fr-CA French (Canada) Chaînes légères d'immunoglobulines.lambda
et-EE Estonian (Estonia) Immuunoglobuliini kerged ahelad.lambda
Synonyms: Immuunglobuliinide kerged lambdaahelad
es-ES Spanish (Spain) Cadenas ligeras de las inmunoglobulinas.lambda
it-IT Italian (Italy) Immunoglobuline, catene leggere.lambda
Synonyms: Catene leggere lambda delle immunoglobuline
tr-TR Turkish (Turkey) İmmünglobulin hafif zincirler.lambda
ru-RU Russian (Russian Federation) Иммуноглобулин легкие цепи.лямбда
nl-NL Dutch (Netherlands) immunoglobuline lichte ketens.lambda
fr-BE French (Belgium) Chaînes légères immunoglobulines.lambda
Synonyms: LC. Lambda
pl-PL Polish (Poland) Łańcuchy lekkie immunoglobuliny.lambda
Synonyms: Łańcuchy lekkie lambda immunoglobuliny