LP15031-5
Immunoglobulin light chains.lambda
Active
Description
All immunoglobulins contain two polypeptide chains: a long (heavy) and a short (light) chain. The two chains interact via disulfide bonds. There are two types of light chains, named kappa and lambda. Serum free light chain (SFLC) testing, a kappa/lambda ratio and a protein electrophoresis test are done to help detect, diagnose and monitor plasma cell disorders (dyscrasias) including multiple myeloma and primary amyloidosis. Normal readings are seen when there is a kappa/lambda ratio of approximately 0.26 to 1.65 and free light chains are present in the blood at low levels. Increased kappa free light chains and an increased kappa/lambda ratio are present with plasma cell disorders that produce excess monoclonal kappa light chains. The tests can also be used to monitor response to treatment. An increase in serum free light chains along with an abnormal kappa/lambda ratio may indicate primary amyloidosis; biopsy of affected tissue is typically used for confirmation of diagnosis. PMID: 6802926 ] [Lab Tests Online:free-light/tab/test] Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Lambda light chains
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Lambda LC
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 免疫球蛋白轻链.Lambda 型 Synonyms: Lambda LC; |
fr-CA | French (Canada) | Chaînes légères d'immunoglobulines.lambda |
et-EE | Estonian (Estonia) | Immuunoglobuliini kerged ahelad.lambda Synonyms: Immuunglobuliinide kerged lambdaahelad |
es-ES | Spanish (Spain) | Cadenas ligeras de las inmunoglobulinas.lambda |
it-IT | Italian (Italy) | Immunoglobuline, catene leggere.lambda Synonyms: Catene leggere lambda delle immunoglobuline |
tr-TR | Turkish (Turkey) | İmmünglobulin hafif zincirler.lambda |
ru-RU | Russian (Russian Federation) | Иммуноглобулин легкие цепи.лямбда |
nl-NL | Dutch (Netherlands) | immunoglobuline lichte ketens.lambda |
fr-BE | French (Belgium) | Chaînes légères immunoglobulines.lambda Synonyms: LC. Lambda |
pl-PL | Polish (Poland) | Łańcuchy lekkie immunoglobuliny.lambda Synonyms: Łańcuchy lekkie lambda immunoglobuliny |
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